Q9H6L4 (ARMC7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Armadillo repeat-containing protein 7

Gene names

Name:

ARMC7

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 2 ARM repeats.

Ontologies

Keywords
Domain	Repeat
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Armadillo repeat-containing protein 7		PRO_0000242666
Regions
	Repeat	57 – 99	43	ARM 1
	Repeat	100 – 140	41	ARM 2
Amino acid modifications
	Modified residue	169	1	Phosphoserine Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q9H6L4 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: B637A76677FE645E	FASTA	198	21,924
	10 20 30 40 50 60 MAQKPKVDPH VGRLGYLQAL VTEFQETQSQ DAKEQVLANL ANFAYDPSNY EYLRQLQVLD 70 80 90 100 110 120 LFLDSLSEEN ETLVEFAIGG LCNLCPDRAN KEHILHAGGV PLIINCLSSP NEETVLSAIT 130 140 150 160 170 180 TLMHLSPPGR SFLPELTATP VVQCMLRFSL SASARLRNLA QIFLEDFCSP RQVAEARSRQ 190 AHSALGIPLP RSVAPRQR

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Skin.
[3]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-169, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK025813 mRNA. Translation: BAB15242.1. BC011728 mRNA. Translation: AAH11728.1.
IPI	IPI00002336.
RefSeq	NP_078861.1. NM_024585.2.
UniGene	Hs.413047.
3D structure databases
ProteinModelPortal	Q9H6L4.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9H6L4. 3 interactions.
MINT	MINT-1447895.
STRING	9606.ENSP00000245543.
PTM databases
PhosphoSite	Q9H6L4.
Polymorphism databases
DMDM	74733612.
Proteomic databases
PaxDb	Q9H6L4.
PRIDE	Q9H6L4.
Protocols and materials databases
DNASU	79637.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000245543; ENSP00000245543; ENSG00000125449.
GeneID	79637.
KEGG	hsa:79637.
UCSC	uc002jmw.1. human.
Organism-specific databases
CTD	79637.
GeneCards	GC17P073106.
HGNC	HGNC:26168. ARMC7.
HPA	HPA024229.
neXtProt	NX_Q9H6L4.
PharmGKB	PA134901380.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG312529.
HOGENOM	HOG000231171.
HOVERGEN	HBG061557.
InParanoid	Q9H6L4.
OMA	RANKEHI.
OrthoDB	EOG4Q2DGP.
PhylomeDB	Q9H6L4.
Gene expression databases
ArrayExpress	Q9H6L4.
Bgee	Q9H6L4.
CleanEx	HS_ARMC7.
Genevestigator	Q9H6L4.
GermOnline	ENSG00000125449. Homo sapiens.
Family and domain databases
Gene3D	1.25.10.10. 1 hit.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000225. Armadillo. [Graphical view]
Pfam	PF00514. Arm. 1 hit. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
PROSITE	PS50176. ARM_REPEAT. False negative. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ARMC7. human.
GenomeRNAi	79637.
NextBio	68753.

Entry information

Entry name

ARMC7_HUMAN

Accession

Primary (citable) accession number: Q9H6L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.