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Q9H633

- RPP21_HUMAN

UniProt

Q9H633 - RPP21_HUMAN

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Protein

Ribonuclease P protein subunit p21

Gene

RPP21

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi62 – 621ZincBy similarity
Metal bindingi65 – 651ZincBy similarity
Metal bindingi92 – 921ZincBy similarity
Metal bindingi95 – 951ZincBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. ribonuclease P activity Source: UniProtKB-EC

GO - Biological processi

  1. response to drug Source: UniProtKB
  2. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p21 (EC:3.1.26.5)
Short name:
RNaseP protein p21
Alternative name(s):
Ribonuclease P/MRP 21 kDa subunit
Ribonucleoprotein V
Gene namesi
Name:RPP21
Synonyms:C6orf135, CAT60
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6, UP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:21300. RPP21.

Subcellular locationi

Nucleusnucleolus 1 Publication

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134960979.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 154153Ribonuclease P protein subunit p21PRO_0000153845Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ9H633.
PaxDbiQ9H633.
PRIDEiQ9H633.

PTM databases

PhosphoSiteiQ9H633.

Expressioni

Gene expression databases

BgeeiQ9H633.
CleanExiHS_RPP21.
GenevestigatoriQ9H633.

Organism-specific databases

HPAiHPA048369.
HPA049389.

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP21, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.

Protein-protein interaction databases

BioGridi122981. 2 interactions.
IntActiQ9H633. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9H633.
SMRiQ9H633. Positions 4-103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG285045.
GeneTreeiENSGT00390000003020.
HOVERGENiHBG055987.
InParanoidiQ9H633.
KOiK03540.
OMAiNYLYQAA.
OrthoDBiEOG75MVZT.
PhylomeDBiQ9H633.

Family and domain databases

InterProiIPR007175. Rpr2.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9H633-1) [UniParc]FASTAAdd to Basket

Also known as: CAT60-V1

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAGPVKDREA FQRLNFLYQA AHCVLAQDPE NQALARFYCY TERTIAKRLV
60 70 80 90 100
LRRDPSVKRT LCRGCSSLLV PGLTCTQRQR RCRGQRWTVQ TCLTCQRSQR
110 120 130 140 150
FLNDPGHLLW GDRPEAQLGS QADSKPLQPL PNTAHSISDR LPEEKMQTQG

SSNQ
Length:154
Mass (Da):17,570
Last modified:March 1, 2001 - v1
Checksum:iF8BD15AA20AE695F
GO
Isoform 2 (identifier: Q9H633-2) [UniParc]FASTAAdd to Basket

Also known as: CAT60-V3

The sequence of this isoform differs from the canonical sequence as follows:
     19-19: Q → QVSLRQGPHGDGARRPRVTAPLPQ

Show »
Length:177
Mass (Da):20,018
Checksum:i0FE5E6F3296602FB
GO
Isoform 3 (identifier: Q9H633-3) [UniParc]FASTAAdd to Basket

Also known as: CAT60-V4

The sequence of this isoform differs from the canonical sequence as follows:
     123-154: DSKPLQPLPNTAHSISDRLPEEKMQTQGSSNQ → GERFQTTTTLAKHSPLHFRPPS

Show »
Length:144
Mass (Da):16,544
Checksum:iB037193A307F6F77
GO
Isoform 4 (identifier: Q9H633-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     52-52: R → RRPLSSSAP

Note: No experimental confirmation available.

Show »
Length:162
Mass (Da):18,366
Checksum:iE2CA143586B0B751
GO

Sequence cautioni

The sequence BI598757 differs from that shown. Reason: Erroneous termination at position 155. Translated as stop.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91E → K in BI598757. (PubMed:15489334)Curated
Sequence conflicti113 – 1131R → Q in CAD44290. 1 PublicationCurated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti77 – 771Q → H.3 Publications
Corresponds to variant rs6986 [ dbSNP | Ensembl ].
VAR_019116
Natural varianti149 – 1491Q → K.1 Publication
Corresponds to variant rs974963 [ dbSNP | Ensembl ].
VAR_045986

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei19 – 191Q → QVSLRQGPHGDGARRPRVTA PLPQ in isoform 2. 1 PublicationVSP_010695
Alternative sequencei52 – 521R → RRPLSSSAP in isoform 4. 1 PublicationVSP_044901
Alternative sequencei123 – 15432DSKPL…GSSNQ → GERFQTTTTLAKHSPLHFRP PS in isoform 3. 1 PublicationVSP_010696Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF212152 mRNA. Translation: AAK39955.2.
AJ504713 mRNA. Translation: CAD44289.1.
AJ504714 mRNA. Translation: CAD44290.1.
AJ504715 mRNA. Translation: CAD44291.1.
AJ504716 mRNA. Translation: CAD44292.1.
AK026291 mRNA. Translation: BAB15433.1.
AL662832 Genomic DNA. Translation: CAI17503.2.
AL662832 Genomic DNA. Translation: CAI17506.2.
AL662832 Genomic DNA. Translation: CAI17507.2.
AL662795 Genomic DNA. Translation: CAI18254.1.
AL662795 Genomic DNA. Translation: CAI18255.2.
AL773535 Genomic DNA. Translation: CAI41822.1.
AL773535 Genomic DNA. Translation: CAI41824.2.
AL662795 Genomic DNA. Translation: CAM25559.1.
BX294158 Genomic DNA. Translation: CAM25886.1.
BX294158 Genomic DNA. Translation: CAM25887.1.
BX294158 Genomic DNA. Translation: CAM25888.1.
BX294158 Genomic DNA. Translation: CAM25889.1.
CR759928 Genomic DNA. Translation: CAQ08317.1.
CR759928 Genomic DNA. Translation: CAQ08318.1.
BX927214 Genomic DNA. Translation: CAQ08386.1.
BX927214 Genomic DNA. Translation: CAQ08387.1.
BX927214 Genomic DNA. Translation: CAQ08388.1.
CR759281 Genomic DNA. Translation: CAQ09024.1.
CR759281 Genomic DNA. Translation: CAQ09025.1.
CH471081 Genomic DNA. Translation: EAX03287.1.
CH471081 Genomic DNA. Translation: EAX03288.1.
CH471081 Genomic DNA. Translation: EAX03289.1.
BC011730 mRNA. Translation: AAH11730.1.
BI598757 mRNA. No translation available.
CCDSiCCDS4679.1. [Q9H633-1]
CCDS56409.1. [Q9H633-4]
CCDS56410.1. [Q9H633-3]
RefSeqiNP_001186049.1. NM_001199120.1. [Q9H633-4]
NP_001186050.1. NM_001199121.1. [Q9H633-3]
NP_079115.1. NM_024839.2. [Q9H633-1]
UniGeneiHs.183232.

Genome annotation databases

EnsembliENST00000376642; ENSP00000365829; ENSG00000239927. [Q9H633-1]
ENST00000411784; ENSP00000412619; ENSG00000241863. [Q9H633-2]
ENST00000414187; ENSP00000398396; ENSG00000243009.
ENST00000415583; ENSP00000403747; ENSG00000239927. [Q9H633-3]
ENST00000416977; ENSP00000404312; ENSG00000241779.
ENST00000424616; ENSP00000399295; ENSG00000241863. [Q9H633-1]
ENST00000425575; ENSP00000405834; ENSG00000239927. [Q9H633-4]
ENST00000428040; ENSP00000394320; ENSG00000241370. [Q9H633-2]
ENST00000430900; ENSP00000415046; ENSG00000239927. [Q9H633-2]
ENST00000433076; ENSP00000409799; ENSG00000241370. [Q9H633-4]
ENST00000434282; ENSP00000414284; ENSG00000242726.
ENST00000435318; ENSP00000411003; ENSG00000239865. [Q9H633-3]
ENST00000436442; ENSP00000397778; ENSG00000241370. [Q9H633-3]
ENST00000437470; ENSP00000408610; ENSG00000241863. [Q9H633-3]
ENST00000442966; ENSP00000403833; ENSG00000241370. [Q9H633-1]
ENST00000455025; ENSP00000409193; ENSG00000241863. [Q9H633-4]
GeneIDi79897.
KEGGihsa:79897.
UCSCiuc003nqd.2. human. [Q9H633-2]
uc003nqe.2. human. [Q9H633-1]
uc003nqf.2. human. [Q9H633-3]
uc021yuc.1. human.

Polymorphism databases

DMDMi52001252.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF212152 mRNA. Translation: AAK39955.2 .
AJ504713 mRNA. Translation: CAD44289.1 .
AJ504714 mRNA. Translation: CAD44290.1 .
AJ504715 mRNA. Translation: CAD44291.1 .
AJ504716 mRNA. Translation: CAD44292.1 .
AK026291 mRNA. Translation: BAB15433.1 .
AL662832 Genomic DNA. Translation: CAI17503.2 .
AL662832 Genomic DNA. Translation: CAI17506.2 .
AL662832 Genomic DNA. Translation: CAI17507.2 .
AL662795 Genomic DNA. Translation: CAI18254.1 .
AL662795 Genomic DNA. Translation: CAI18255.2 .
AL773535 Genomic DNA. Translation: CAI41822.1 .
AL773535 Genomic DNA. Translation: CAI41824.2 .
AL662795 Genomic DNA. Translation: CAM25559.1 .
BX294158 Genomic DNA. Translation: CAM25886.1 .
BX294158 Genomic DNA. Translation: CAM25887.1 .
BX294158 Genomic DNA. Translation: CAM25888.1 .
BX294158 Genomic DNA. Translation: CAM25889.1 .
CR759928 Genomic DNA. Translation: CAQ08317.1 .
CR759928 Genomic DNA. Translation: CAQ08318.1 .
BX927214 Genomic DNA. Translation: CAQ08386.1 .
BX927214 Genomic DNA. Translation: CAQ08387.1 .
BX927214 Genomic DNA. Translation: CAQ08388.1 .
CR759281 Genomic DNA. Translation: CAQ09024.1 .
CR759281 Genomic DNA. Translation: CAQ09025.1 .
CH471081 Genomic DNA. Translation: EAX03287.1 .
CH471081 Genomic DNA. Translation: EAX03288.1 .
CH471081 Genomic DNA. Translation: EAX03289.1 .
BC011730 mRNA. Translation: AAH11730.1 .
BI598757 mRNA. No translation available.
CCDSi CCDS4679.1. [Q9H633-1 ]
CCDS56409.1. [Q9H633-4 ]
CCDS56410.1. [Q9H633-3 ]
RefSeqi NP_001186049.1. NM_001199120.1. [Q9H633-4 ]
NP_001186050.1. NM_001199121.1. [Q9H633-3 ]
NP_079115.1. NM_024839.2. [Q9H633-1 ]
UniGenei Hs.183232.

3D structure databases

ProteinModelPortali Q9H633.
SMRi Q9H633. Positions 4-103.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 122981. 2 interactions.
IntActi Q9H633. 1 interaction.

PTM databases

PhosphoSitei Q9H633.

Polymorphism databases

DMDMi 52001252.

Proteomic databases

MaxQBi Q9H633.
PaxDbi Q9H633.
PRIDEi Q9H633.

Protocols and materials databases

DNASUi 79897.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000376642 ; ENSP00000365829 ; ENSG00000239927 . [Q9H633-1 ]
ENST00000411784 ; ENSP00000412619 ; ENSG00000241863 . [Q9H633-2 ]
ENST00000414187 ; ENSP00000398396 ; ENSG00000243009 .
ENST00000415583 ; ENSP00000403747 ; ENSG00000239927 . [Q9H633-3 ]
ENST00000416977 ; ENSP00000404312 ; ENSG00000241779 .
ENST00000424616 ; ENSP00000399295 ; ENSG00000241863 . [Q9H633-1 ]
ENST00000425575 ; ENSP00000405834 ; ENSG00000239927 . [Q9H633-4 ]
ENST00000428040 ; ENSP00000394320 ; ENSG00000241370 . [Q9H633-2 ]
ENST00000430900 ; ENSP00000415046 ; ENSG00000239927 . [Q9H633-2 ]
ENST00000433076 ; ENSP00000409799 ; ENSG00000241370 . [Q9H633-4 ]
ENST00000434282 ; ENSP00000414284 ; ENSG00000242726 .
ENST00000435318 ; ENSP00000411003 ; ENSG00000239865 . [Q9H633-3 ]
ENST00000436442 ; ENSP00000397778 ; ENSG00000241370 . [Q9H633-3 ]
ENST00000437470 ; ENSP00000408610 ; ENSG00000241863 . [Q9H633-3 ]
ENST00000442966 ; ENSP00000403833 ; ENSG00000241370 . [Q9H633-1 ]
ENST00000455025 ; ENSP00000409193 ; ENSG00000241863 . [Q9H633-4 ]
GeneIDi 79897.
KEGGi hsa:79897.
UCSCi uc003nqd.2. human. [Q9H633-2 ]
uc003nqe.2. human. [Q9H633-1 ]
uc003nqf.2. human. [Q9H633-3 ]
uc021yuc.1. human.

Organism-specific databases

CTDi 79897.
GeneCardsi GC06P030312.
GC06Pi30321.
GC06Pj30302.
GC06Pk30303.
GC06Pl30357.
GC06Pn30302.
GC06Po30302.
H-InvDB HIX0207610.
HIX0207675.
HIX0207761.
HGNCi HGNC:21300. RPP21.
HPAi HPA048369.
HPA049389.
MIMi 612524. gene.
neXtProti NX_Q9H633.
PharmGKBi PA134960979.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG285045.
GeneTreei ENSGT00390000003020.
HOVERGENi HBG055987.
InParanoidi Q9H633.
KOi K03540.
OMAi NYLYQAA.
OrthoDBi EOG75MVZT.
PhylomeDBi Q9H633.

Miscellaneous databases

GenomeRNAii 79897.
NextBioi 69734.
PROi Q9H633.
SOURCEi Search...

Gene expression databases

Bgeei Q9H633.
CleanExi HS_RPP21.
Genevestigatori Q9H633.

Family and domain databases

InterProi IPR007175. Rpr2.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Function and subnuclear distribution of Rpp21, a protein subunit of the human ribonucleoprotein ribonuclease P."
    Jarrous N., Reiner R., Wesolowski D., Mann H., Guerrier-Takada C., Altman S.
    RNA 7:1153-1164(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
  2. "Genes from major histocompatibility complex (MHC) class I region from HLA-C to HLA-A."
    Raha-Chowdhury R., Andrews S.R., Gruen J.R., Weissman S.M.
    Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), VARIANT HIS-77.
    Tissue: Spleen.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Small intestine.
  4. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS HIS-77 AND LYS-149.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4), VARIANT HIS-77.
    Tissue: Hypothalamus and Skin.
  7. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRPP21_HUMAN
AccessioniPrimary (citable) accession number: Q9H633
Secondary accession number(s): A2AAZ8
, B0S834, B0S835, Q5JPL9, Q5JPM1, Q5STF8, Q5STF9, Q5STG2, Q5SU41, Q5SU42, Q86Y49, Q86Y50, Q86Y51, Q96F16
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: March 1, 2001
Last modified: November 26, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

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