Q9H607 (OCEL1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Occludin/ELL domain-containing protein 1

Gene names

Name:

OCEL1

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ELL/occludin family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	Occludin/ELL domain-containing protein 1		PRO_0000271531
Regions
	Compositional bias	28 – 106	79	Pro-rich
Natural variations
	Natural variant	42	1	R → L. Corresponds to variant rs10425488 [ dbSNP | Ensembl ].		VAR_034356
	Natural variant	109	1	A → G. Corresponds to variant rs891203 [ dbSNP | Ensembl ].		VAR_034357

Sequences

	Sequence		Length	Mass (Da)
	Q9H607 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 7B25A634A844B1E7	FASTA	264	29,404
	10 20 30 40 50 60 MHNPDGSASP TADPGSELQT LGQAARRPPP PRAGHDAPRR TRPSARKPLS CFSRRPMPTR 70 80 90 100 110 120 EPPKTRGSRG HLHTHPPGPG PPLQGLAPRG LKTSAPRPPC QPQPGPHKAK TKKIVFEDEL 130 140 150 160 170 180 LSQALLGAKK PIGAIPKGHK PRPHPVPDYE LKYPPVSSER ERSRYVAVFQ DQYGEFLELQ 190 200 210 220 230 240 HEVGCAQAKL RQLEALLSSL PPPQSQKEAQ VAARVWREFE MKRMDPGFLD KQARCHYLKG 250 260 KLRHLKTQIQ KFDDQGDSEG SVYF

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Small intestine.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Bone marrow.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK026362 mRNA. Translation: BAB15460.1. BC029361 mRNA. Translation: AAH29361.1.
IPI	IPI00002305.
RefSeq	NP_078854.1. NM_024578.1.
UniGene	Hs.422676.
3D structure databases
ProteinModelPortal	Q9H607.
SMR	Q9H607. Positions 148-257.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9H607.
Polymorphism databases
DMDM	74733590.
Proteomic databases
PRIDE	Q9H607.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000215061; ENSP00000215061; ENSG00000099330.
GeneID	79629.
KEGG	hsa:79629.
UCSC	uc002nfp.1. human.
Organism-specific databases
CTD	79629.
GeneCards	GC19P017337.
HGNC	HGNC:26221. OCEL1.
neXtProt	NX_Q9H607.
PharmGKB	PA162398385.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG06479.
GeneTree	ENSGT00550000074378.
HOVERGEN	HBG082082.
InParanoid	Q9H607.
OMA	ARCHYLK.
OrthoDB	EOG4HHP3B.
PhylomeDB	Q9H607.
Gene expression databases
ArrayExpress	Q9H607.
Bgee	Q9H607.
CleanEx	HS_OCEL1.
Genevestigator	Q9H607.
Family and domain databases
InterPro	IPR010844. Occludin_RNApol2_elong_fac_ELL. [Graphical view]
Pfam	PF07303. Occludin_ELL. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	68721.

Entry information

Entry name

OCEL1_HUMAN

Accession

Primary (citable) accession number: Q9H607

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	March 1, 2001
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.