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Q9H5F2 (CK001_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0686 protein C11orf1
Gene names
Name:C11orf1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus Ref.1.

Sequence similarities

Belongs to the UPF0686 family.

Ontologies

Keywords
   Cellular componentNucleus
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Non-traceable author statement Ref.1. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 150150UPF0686 protein C11orf1
PRO_0000089829

Natural variations

Natural variant401V → A. Ref.1 Ref.3
Corresponds to variant rs9280 [ dbSNP | Ensembl ].
VAR_054163
Natural variant491K → Q.
Corresponds to variant rs11540721 [ dbSNP | Ensembl ].
VAR_050861
Natural variant851Q → H.
Corresponds to variant rs3180820 [ dbSNP | Ensembl ].
VAR_050862

Sequences

Sequence LengthMass (Da)Tools
Q9H5F2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: BB1D0B7EDE8F2C7B

FASTA15017,785
        10         20         30         40         50         60 
MAASQCLCCS KFLFQRQNLA CFLTNPHCGS LVNADGHGEV WTDWNNMSKF FQYGWRCTTN 

        70         80         90        100        110        120 
ENTYSNRTLM GNWNQERYDL RNIVQPKPLP SQFGHYFETT YDTSYNNKMP LSTHRFKREP 

       130        140        150 
HWFPGHQPEL DPPRYKCTEK STYMNSYSKP 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of five novel human genes in the 11q13-q22 region."
O'Brien K.P., Tapia-Paez I., Staahle-Baeckdahl M., Kedra D., Dumanski J.P.
Biochem. Biophys. Res. Commun. 273:90-94(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, VARIANT ALA-40.
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung.
[3]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-40.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryonic testis carcinoma.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ250229 mRNA. Translation: CAB96538.1.
AK027152 mRNA. Translation: BAB15674.1.
CR457378 mRNA. Translation: CAG33659.1.
BC020628 mRNA. Translation: AAH20628.1.
CCDSCCDS8350.1.
RefSeqNP_073598.1. NM_022761.2.
UniGeneHs.17546.

3D structure databases

ProteinModelPortalQ9H5F2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122286. 1 interaction.
IntActQ9H5F2. 1 interaction.
MINTMINT-1385135.
STRING9606.ENSP00000260276.

PTM databases

PhosphoSiteQ9H5F2.

Polymorphism databases

DMDM47605552.

Proteomic databases

PaxDbQ9H5F2.
PRIDEQ9H5F2.

Protocols and materials databases

DNASU64776.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000260276; ENSP00000260276; ENSG00000137720.
ENST00000570851; ENSP00000459272; ENSG00000262176.
GeneID64776.
KEGGhsa:64776.
UCSCuc001pmd.3. human.

Organism-specific databases

CTD64776.
GeneCardsGC11P111749.
H-InvDBHIX0010114.
HGNCHGNC:1163. C11orf1.
HPAHPA038410.
neXtProtNX_Q9H5F2.
PharmGKBPA25477.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG39668.
HOGENOMHOG000067902.
HOVERGENHBG050969.
InParanoidQ9H5F2.
PhylomeDBQ9H5F2.
TreeFamTF329225.

Gene expression databases

ArrayExpressQ9H5F2.
BgeeQ9H5F2.
CleanExHS_C11orf1.
GenevestigatorQ9H5F2.

Family and domain databases

InterProIPR009524. UPF0686.
[Graphical view]
PfamPF06608. DUF1143. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GeneWikiC11orf1.
GenomeRNAi64776.
NextBio66794.

Entry information

Entry nameCK001_HUMAN
AccessionPrimary (citable) accession number: Q9H5F2
Secondary accession number(s): Q6I9X7, Q9NQC6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM