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Protein

UPF0686 protein C11orf1

Gene

C11orf1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0686 protein C11orf1
Gene namesi
Name:C11orf1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1163. C11orf1.

Subcellular locationi

  1. Nucleus 1 Publication

GO - Cellular componenti

  1. nucleoplasm Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25477.

Polymorphism and mutation databases

BioMutaiC11orf1.
DMDMi47605552.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 150150UPF0686 protein C11orf1PRO_0000089829Add
BLAST

Proteomic databases

PaxDbiQ9H5F2.
PRIDEiQ9H5F2.

PTM databases

PhosphoSiteiQ9H5F2.

Expressioni

Gene expression databases

BgeeiQ9H5F2.
CleanExiHS_C11orf1.
ExpressionAtlasiQ9H5F2. baseline and differential.
GenevestigatoriQ9H5F2.

Organism-specific databases

HPAiHPA038410.
HPA057519.

Interactioni

Protein-protein interaction databases

BioGridi122286. 1 interaction.
IntActiQ9H5F2. 1 interaction.
MINTiMINT-1385135.
STRINGi9606.ENSP00000260276.

Structurei

3D structure databases

ProteinModelPortaliQ9H5F2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0686 family.Curated

Phylogenomic databases

eggNOGiNOG39668.
GeneTreeiENSGT00390000002905.
HOGENOMiHOG000067902.
HOVERGENiHBG050969.
InParanoidiQ9H5F2.
PhylomeDBiQ9H5F2.
TreeFamiTF329225.

Family and domain databases

InterProiIPR009524. UPF0686.
[Graphical view]
PfamiPF06608. DUF1143. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H5F2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASQCLCCS KFLFQRQNLA CFLTNPHCGS LVNADGHGEV WTDWNNMSKF
60 70 80 90 100
FQYGWRCTTN ENTYSNRTLM GNWNQERYDL RNIVQPKPLP SQFGHYFETT
110 120 130 140 150
YDTSYNNKMP LSTHRFKREP HWFPGHQPEL DPPRYKCTEK STYMNSYSKP
Length:150
Mass (Da):17,785
Last modified:March 1, 2001 - v1
Checksum:iBB1D0B7EDE8F2C7B
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti40 – 401V → A.2 Publications
Corresponds to variant rs9280 [ dbSNP | Ensembl ].
VAR_054163
Natural varianti49 – 491K → Q.
Corresponds to variant rs11540721 [ dbSNP | Ensembl ].
VAR_050861
Natural varianti85 – 851Q → H.
Corresponds to variant rs3180820 [ dbSNP | Ensembl ].
VAR_050862

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250229 mRNA. Translation: CAB96538.1.
AK027152 mRNA. Translation: BAB15674.1.
CR457378 mRNA. Translation: CAG33659.1.
BC020628 mRNA. Translation: AAH20628.1.
CCDSiCCDS8350.1.
RefSeqiNP_073598.1. NM_022761.2.
UniGeneiHs.17546.

Genome annotation databases

EnsembliENST00000260276; ENSP00000260276; ENSG00000137720.
GeneIDi64776.
KEGGihsa:64776.
UCSCiuc001pmd.3. human.

Polymorphism and mutation databases

BioMutaiC11orf1.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250229 mRNA. Translation: CAB96538.1.
AK027152 mRNA. Translation: BAB15674.1.
CR457378 mRNA. Translation: CAG33659.1.
BC020628 mRNA. Translation: AAH20628.1.
CCDSiCCDS8350.1.
RefSeqiNP_073598.1. NM_022761.2.
UniGeneiHs.17546.

3D structure databases

ProteinModelPortaliQ9H5F2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122286. 1 interaction.
IntActiQ9H5F2. 1 interaction.
MINTiMINT-1385135.
STRINGi9606.ENSP00000260276.

PTM databases

PhosphoSiteiQ9H5F2.

Polymorphism and mutation databases

BioMutaiC11orf1.
DMDMi47605552.

Proteomic databases

PaxDbiQ9H5F2.
PRIDEiQ9H5F2.

Protocols and materials databases

DNASUi64776.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000260276; ENSP00000260276; ENSG00000137720.
GeneIDi64776.
KEGGihsa:64776.
UCSCiuc001pmd.3. human.

Organism-specific databases

CTDi64776.
GeneCardsiGC11P111749.
H-InvDBHIX0010114.
HGNCiHGNC:1163. C11orf1.
HPAiHPA038410.
HPA057519.
neXtProtiNX_Q9H5F2.
PharmGKBiPA25477.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG39668.
GeneTreeiENSGT00390000002905.
HOGENOMiHOG000067902.
HOVERGENiHBG050969.
InParanoidiQ9H5F2.
PhylomeDBiQ9H5F2.
TreeFamiTF329225.

Miscellaneous databases

GeneWikiiC11orf1.
GenomeRNAii64776.
NextBioi66794.
PROiQ9H5F2.

Gene expression databases

BgeeiQ9H5F2.
CleanExiHS_C11orf1.
ExpressionAtlasiQ9H5F2. baseline and differential.
GenevestigatoriQ9H5F2.

Family and domain databases

InterProiIPR009524. UPF0686.
[Graphical view]
PfamiPF06608. DUF1143. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, VARIANT ALA-40.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.
  3. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-40.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryonic testis carcinoma.

Entry informationi

Entry nameiCK001_HUMAN
AccessioniPrimary (citable) accession number: Q9H5F2
Secondary accession number(s): Q6I9X7, Q9NQC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2001
Last modified: April 29, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.