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Protein

Zinc finger protein 644

Gene

ZNF644

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri410 – 432C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 470C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri496 – 518C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri525 – 548C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri586 – 609C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri963 – 987C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri1038 – 1060C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 644
Alternative name(s):
Zinc finger motif enhancer-binding protein 2
Short name:
Zep-2
Gene namesi
Name:ZNF644
Synonyms:KIAA1221, ZEP2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:29222. ZNF644.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Involvement in diseasei

Myopia 21, autosomal dominant (MYP21)4 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far.
See also OMIM:614167
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_073995242T → M in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs143932357dbSNPEnsembl.1
Natural variantiVAR_073996274E → V in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs774685437dbSNPEnsembl.1
Natural variantiVAR_073997305E → K in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs149597385dbSNPEnsembl.1
Natural variantiVAR_073999401T → A in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_066389587I → V in MYP21. 1 PublicationCorresponds to variant rs146936371dbSNPEnsembl.1
Natural variantiVAR_066390672S → G in MYP21. 2 PublicationsCorresponds to variant rs387907109dbSNPEnsembl.1
Natural variantiVAR_066391680R → G in MYP21. 1 Publication1
Natural variantiVAR_074001683R → T in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs201546602dbSNPEnsembl.1
Natural variantiVAR_066392699C → Y in MYP21. 1 Publication1
Natural variantiVAR_074004851D → H in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_074005956T → S in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_0740061089Y → C in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs193167060dbSNPEnsembl.1
Natural variantiVAR_0740081278E → G in MYP21; unknown pathological significance. 1 Publication1

Keywords - Diseasei

Disease mutation

Organism-specific databases

DisGeNETi84146.
MalaCardsiZNF644.
MIMi614167. phenotype.
OpenTargetsiENSG00000122482.
PharmGKBiPA134984168.

Polymorphism and mutation databases

BioMutaiZNF644.
DMDMi56404958.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000476981 – 1327Zinc finger protein 644Add BLAST1327

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki39Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei199PhosphoserineCombined sources1
Modified residuei309PhosphoserineCombined sources1
Cross-linki319Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki339Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki346Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Cross-linki346Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki553Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki627Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki641Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki645Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki658Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki712Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki718Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki733Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki762Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei820PhosphoserineCombined sources1
Modified residuei1000PhosphoserineCombined sources1
Cross-linki1094Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei1189PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9H582.
MaxQBiQ9H582.
PaxDbiQ9H582.
PeptideAtlasiQ9H582.
PRIDEiQ9H582.

PTM databases

iPTMnetiQ9H582.
PhosphoSitePlusiQ9H582.

Expressioni

Tissue specificityi

Expressed in liver, placenta, retina and retinal pigment epithelium.1 Publication

Gene expression databases

BgeeiENSG00000122482.
CleanExiHS_ZNF644.
ExpressionAtlasiQ9H582. baseline and differential.
GenevisibleiQ9H582. HS.

Organism-specific databases

HPAiHPA057795.

Interactioni

Protein-protein interaction databases

BioGridi123913. 48 interactors.
IntActiQ9H582. 25 interactors.
MINTiMINT-4658204.
STRINGi9606.ENSP00000337008.

Structurei

3D structure databases

ProteinModelPortaliQ9H582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 7 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri410 – 432C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 470C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri496 – 518C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri525 – 548C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri586 – 609C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri963 – 987C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri1038 – 1060C2H2-type 7PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063587.
HOVERGENiHBG058603.
InParanoidiQ9H582.
OMAiCCEECNF.
OrthoDBiEOG091G00M4.
PhylomeDBiQ9H582.
TreeFamiTF333705.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9H582-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRSFLQQDVN KTKSRLNVLN GLANNMDDLK INTDITGAKE ELLDDNNFIS
60 70 80 90 100
DKESGVHKPK DCQTSFQKNN TLTLPEELSK DKSENALSGG QSSLFIHAGA
110 120 130 140 150
PTVSSENFIL PKGAAVNGPV SHSSLTKTSN MNKGSVSLTT GQPVDQPTTE
160 170 180 190 200
SCSTLKVAAD LQLSTPQKAS QHQVLFLLSD VAHAKNPTHS NKKLPTSASV
210 220 230 240 250
GCDIQNSVGS NIKSDGTLIN QVEVGEDGED LLVKDDCVNT VTGISSGTDG
260 270 280 290 300
FRSENDTNWD PQKEFIQFLM TNEETVDKAP PHSKIGLEKK RKRKMDVSKI
310 320 330 340 350
TRYTEDCFSD SNCVPNKSKM QEVDFLEQNE ELQAVDSQKY ALSKVKPEST
360 370 380 390 400
DEDLESVDAF QHLIYNPDKC GEESSPVHTS TFLSNTLKKK CEESDSESPA
410 420 430 440 450
TFSTEEPSFY PCTKCNVNFR EKKHLHRHMM YHLDGNSHFR HLNVPRPYAC
460 470 480 490 500
RECGRTFRDR NSLLKHMIIH QERRQKLMEE IRELKELQDE GRSARLQCPQ
510 520 530 540 550
CVFGTNCPKT FVQHAKTHEK DKRYYCCEEC NFMAVTENEL ECHRGIAHGA
560 570 580 590 600
VVKCPMVTSD IAQRKTQKKT FMKDSVVGSS KKSATYICKM CPFTTSAKSV
610 620 630 640 650
LKKHTEYLHS SSCVDSFGSP LGLDKRKNDI LEEPVDSDST KTLTKQQSTT
660 670 680 690 700
FPKNSALKQD VKRTFGSTSQ SSSFSKIHKR PHRIQKARKS IAQSGVNMCN
710 720 730 740 750
QNSSPHKNVT IKSSVDQKPK YFHQAAKEKS NAKANSHYLY RHKYENYRMI
760 770 780 790 800
KKSGESYPVH FKKEEASSLN SLHLFSSSSN SHNNFISDPH KPDAKRPESF
810 820 830 840 850
KDHRRVAVKR VIKESKKESS VGGEDLDSYP DFLHKMTVVV LQKLNSAEKK
860 870 880 890 900
DSYETEDESS WDNVELGDYT TQAIEDETYS DINQEHVNLF PLFKSKVEGQ
910 920 930 940 950
EPGENATLSY DQNDGFYFEY YEDTGSNNFL HEIHDPQHLE TADASLSKHS
960 970 980 990 1000
SVFHWTDLSL EKKSCPYCPA TFETGVGLSN HVRGHLHRAG LSYEARHVVS
1010 1020 1030 1040 1050
PEQIATSDKM QHFKRTGTGT PVKRVRKAIE KSETTSEHTC QLCGGWFDTK
1060 1070 1080 1090 1100
IGLSNHVRGH LKRLGKTKWD AHKSPICVLN EMMQNEEKYE KILKALNSRR
1110 1120 1130 1140 1150
IIPRPFVAQK LASSDDFISQ NVIPLEAYRN GLKTEALSVS ASEEEGLNFL
1160 1170 1180 1190 1200
NEYDETKPEL PSGKKNQSLT LIELLKNKRM GEERNSAISP QKIHNQTARK
1210 1220 1230 1240 1250
RFVQKCVLPL NEDSPLMYQP QKMDLTMHSA LDCKQKKSRS RSGSKKKMLT
1260 1270 1280 1290 1300
LPHGADEVYI LRCRFCGLVF RGPLSVQEDW IKHLQRHIVN ANLPRTGAGM
1310 1320
VEVTSLLKKP ASITETSFSL LMAEAAS
Length:1,327
Mass (Da):149,565
Last modified:December 7, 2004 - v2
Checksum:i53CE36BE21FC5056
GO
Isoform 2 (identifier: Q9H582-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1230-1232: ALD → GLI
     1233-1327: Missing.

Show »
Length:1,232
Mass (Da):139,012
Checksum:i50D719F07AF12CBA
GO
Isoform 3 (identifier: Q9H582-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1222: Missing.
     1223-1229: MDLTMHS → MLIRQNL

Show »
Length:105
Mass (Da):11,724
Checksum:i237D95A0CC5CAD1D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti296D → M in BAD32777 (Ref. 1) Curated1
Sequence conflicti1125L → P in BAD32777 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03559353E → Q in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_073995242T → M in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs143932357dbSNPEnsembl.1
Natural variantiVAR_073996274E → V in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs774685437dbSNPEnsembl.1
Natural variantiVAR_073997305E → K in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs149597385dbSNPEnsembl.1
Natural variantiVAR_073998369K → M Polymorphism. 1 Publication1
Natural variantiVAR_073999401T → A in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_074000550A → T Polymorphism. 1 PublicationCorresponds to variant rs754440728dbSNPEnsembl.1
Natural variantiVAR_052885556M → V.Corresponds to variant rs17131242dbSNPEnsembl.1
Natural variantiVAR_066389587I → V in MYP21. 1 PublicationCorresponds to variant rs146936371dbSNPEnsembl.1
Natural variantiVAR_066390672S → G in MYP21. 2 PublicationsCorresponds to variant rs387907109dbSNPEnsembl.1
Natural variantiVAR_066391680R → G in MYP21. 1 Publication1
Natural variantiVAR_074001683R → T in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs201546602dbSNPEnsembl.1
Natural variantiVAR_066392699C → Y in MYP21. 1 Publication1
Natural variantiVAR_074002706H → Y.1 Publication1
Natural variantiVAR_074003707K → E.1 PublicationCorresponds to variant rs12117237dbSNPEnsembl.1
Natural variantiVAR_052886794A → V.Corresponds to variant rs10922938dbSNPEnsembl.1
Natural variantiVAR_074004851D → H in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_074005956T → S in MYP21; unknown pathological significance. 1 Publication1
Natural variantiVAR_0740061089Y → C in MYP21; unknown pathological significance. 1 PublicationCorresponds to variant rs193167060dbSNPEnsembl.1
Natural variantiVAR_0740071100R → H.1 PublicationCorresponds to variant rs140271599dbSNPEnsembl.1
Natural variantiVAR_0740081278E → G in MYP21; unknown pathological significance. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0158551 – 1222Missing in isoform 3. 2 PublicationsAdd BLAST1222
Alternative sequenceiVSP_0158561223 – 1229MDLTMHS → MLIRQNL in isoform 3. 2 Publications7
Alternative sequenceiVSP_0121581230 – 1232ALD → GLI in isoform 2. 1 Publication3
Alternative sequenceiVSP_0121591233 – 1327Missing in isoform 2. 1 PublicationAdd BLAST95

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB019255 mRNA. Translation: BAD32777.1.
AK291520 mRNA. Translation: BAF84209.1.
AL136109 Genomic DNA. Translation: CAI23362.1.
AL136109 Genomic DNA. Translation: CAI23363.1.
CH471097 Genomic DNA. Translation: EAW73118.1.
BC050656 mRNA. Translation: AAH50656.1.
BC063683 mRNA. Translation: AAH63683.2.
BC110841 mRNA. Translation: AAI10842.1.
BC132776 mRNA. Translation: AAI32777.1.
BC132778 mRNA. Translation: AAI32779.1.
AB033047 mRNA. Translation: BAA86535.1.
CCDSiCCDS731.1. [Q9H582-1]
CCDS732.1. [Q9H582-3]
RefSeqiNP_057704.2. NM_016620.3. [Q9H582-3]
NP_115562.3. NM_032186.4. [Q9H582-3]
NP_958357.1. NM_201269.2. [Q9H582-1]
XP_016857977.1. XM_017002488.1. [Q9H582-1]
XP_016857978.1. XM_017002489.1. [Q9H582-1]
XP_016857979.1. XM_017002490.1. [Q9H582-1]
XP_016857980.1. XM_017002491.1. [Q9H582-1]
XP_016857981.1. XM_017002492.1. [Q9H582-3]
XP_016857982.1. XM_017002493.1. [Q9H582-3]
XP_016857983.1. XM_017002494.1. [Q9H582-3]
UniGeneiHs.173001.
Hs.745048.

Genome annotation databases

EnsembliENST00000337393; ENSP00000337008; ENSG00000122482. [Q9H582-1]
ENST00000347275; ENSP00000340828; ENSG00000122482. [Q9H582-3]
ENST00000361321; ENSP00000354659; ENSG00000122482. [Q9H582-3]
ENST00000370440; ENSP00000359469; ENSG00000122482. [Q9H582-1]
GeneIDi84146.
KEGGihsa:84146.
UCSCiuc001dnv.4. human. [Q9H582-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB019255 mRNA. Translation: BAD32777.1.
AK291520 mRNA. Translation: BAF84209.1.
AL136109 Genomic DNA. Translation: CAI23362.1.
AL136109 Genomic DNA. Translation: CAI23363.1.
CH471097 Genomic DNA. Translation: EAW73118.1.
BC050656 mRNA. Translation: AAH50656.1.
BC063683 mRNA. Translation: AAH63683.2.
BC110841 mRNA. Translation: AAI10842.1.
BC132776 mRNA. Translation: AAI32777.1.
BC132778 mRNA. Translation: AAI32779.1.
AB033047 mRNA. Translation: BAA86535.1.
CCDSiCCDS731.1. [Q9H582-1]
CCDS732.1. [Q9H582-3]
RefSeqiNP_057704.2. NM_016620.3. [Q9H582-3]
NP_115562.3. NM_032186.4. [Q9H582-3]
NP_958357.1. NM_201269.2. [Q9H582-1]
XP_016857977.1. XM_017002488.1. [Q9H582-1]
XP_016857978.1. XM_017002489.1. [Q9H582-1]
XP_016857979.1. XM_017002490.1. [Q9H582-1]
XP_016857980.1. XM_017002491.1. [Q9H582-1]
XP_016857981.1. XM_017002492.1. [Q9H582-3]
XP_016857982.1. XM_017002493.1. [Q9H582-3]
XP_016857983.1. XM_017002494.1. [Q9H582-3]
UniGeneiHs.173001.
Hs.745048.

3D structure databases

ProteinModelPortaliQ9H582.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123913. 48 interactors.
IntActiQ9H582. 25 interactors.
MINTiMINT-4658204.
STRINGi9606.ENSP00000337008.

PTM databases

iPTMnetiQ9H582.
PhosphoSitePlusiQ9H582.

Polymorphism and mutation databases

BioMutaiZNF644.
DMDMi56404958.

Proteomic databases

EPDiQ9H582.
MaxQBiQ9H582.
PaxDbiQ9H582.
PeptideAtlasiQ9H582.
PRIDEiQ9H582.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000337393; ENSP00000337008; ENSG00000122482. [Q9H582-1]
ENST00000347275; ENSP00000340828; ENSG00000122482. [Q9H582-3]
ENST00000361321; ENSP00000354659; ENSG00000122482. [Q9H582-3]
ENST00000370440; ENSP00000359469; ENSG00000122482. [Q9H582-1]
GeneIDi84146.
KEGGihsa:84146.
UCSCiuc001dnv.4. human. [Q9H582-1]

Organism-specific databases

CTDi84146.
DisGeNETi84146.
GeneCardsiZNF644.
HGNCiHGNC:29222. ZNF644.
HPAiHPA057795.
MalaCardsiZNF644.
MIMi614159. gene.
614167. phenotype.
neXtProtiNX_Q9H582.
OpenTargetsiENSG00000122482.
PharmGKBiPA134984168.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063587.
HOVERGENiHBG058603.
InParanoidiQ9H582.
OMAiCCEECNF.
OrthoDBiEOG091G00M4.
PhylomeDBiQ9H582.
TreeFamiTF333705.

Miscellaneous databases

ChiTaRSiZNF644. human.
GeneWikiiZNF644.
GenomeRNAii84146.
PROiQ9H582.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000122482.
CleanExiHS_ZNF644.
ExpressionAtlasiQ9H582. baseline and differential.
GenevisibleiQ9H582. HS.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN644_HUMAN
AccessioniPrimary (citable) accession number: Q9H582
Secondary accession number(s): A2RU71
, Q2TAM0, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 30, 2016
This is version 134 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.