Reviewed,
UniProtKB/Swiss-Prot Q9H503 (BAFL_HUMAN)
Last modified
December 15, 2009.
Version 62.
History...
Clusters with 100%,
90%,
50% identity |
Documents (4) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Barrier-to-autointegration factor-like protein Short name=BAF-L Alternative name(s): Barrier-to-autointegration factor 2 | ||||
| Gene names |
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| Organism | Homo sapiens (Human) [Complete proteome] | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 90 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | May play a role in BANF1 regulation and influence tissue-specific roles of BANF1. |
| Subunit structure | Homodimer. Heterodimerizes with BANF1. |
| Subcellular location | |
| Tissue specificity | Expressed strongly in testis and pancreas. Also detected in brain, colon, liver, lung, ovary, placenta, prostate, small intestine, spleen and thymus. Not detected in heart, kidney and skeletal muscle. |
| Sequence similarities | Belongs to the BAF family. |
| Caution | In contrast to BANF1, it does not seems to bind DNA. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm Nucleus |
| Coding sequence diversity | Polymorphism |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleusInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| « Hide 'large scale' references | |
| [1] | "The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. Rogers J.Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [2] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis. |
| [3] | "Barrier-to-autointegration factor-like (BAF-L): a proposed regulator of BAF." Tifft K.E., Segura-Totten M., Lee K.K., Wilson K.L. Exp. Cell Res. 312:478-487(2006) [PubMed: 16337940] [Abstract] Cited for: CHARACTERIZATION, INTERACTION WITH BANF1. |
Cross-references
Sequence databases | |
|---|---|
| AL160071 Genomic DNA. Translation: CAC15540.1. BC054871 mRNA. Translation: AAH54871.1. BC062735 mRNA. Translation: AAH62735.1. | |
| IPI | IPI00014735. |
| RefSeq | NP_001014977.2. NP_001152967.1. NP_848572.3. |
| UniGene | Hs.115366 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9H503. |
Proteomic databases | |
| PRIDE | Q9H503. |
Genome annotation databases | |
| Ensembl | ENST00000246090; ENSP00000246090; ENSG00000125888; Homo sapiens. [Genome view] ENST00000377805; ENSP00000367036; ENSG00000125888; Homo sapiens. [Genome view] |
| GeneID | 140836. |
| KEGG | hsa:140836. |
| UCSC | uc002wpz.1. human. |
Organism-specific databases | |
| CTD | 140836. |
| GeneCards | GC20P017630. |
| H-InvDB | HIX0027767. |
| HGNC | HGNC:16172. BANF2. |
| PharmGKB | PA25722. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOGENOM | HBG381393. |
| HOVERGEN | Q9H503. |
| InParanoid | Q9H503. |
| OMA | CCGATEC. |
Gene expression databases | |
| ArrayExpress | Q9H503. |
| Bgee | Q9H503. |
| CleanEx | HS_BANF2. |
| Genevestigator | Q9H503. |
| GermOnline | ENSG00000125888. Homo sapiens. |
Family and domain databases | |
| InterPro | IPR004122. BAF_prot. [Graphical view] |
| Gene3D | G3DSA:1.10.150.40. BAF_prot. 1 hit. |
| PANTHER | PTHR12912. BAF_prot. 1 hit. |
| Pfam | PF02961. BAF. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 84454. |
Entry information
| Entry name | BAFL_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q9H503 Secondary accession number(s): Q7Z4M6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Human chromosome 20 Human chromosome 20: entries, gene names and cross-references to MIM |
| Human entries with polymorphisms or disease mutations List of human entries with polymorphisms or disease mutations |
| Human polymorphisms and disease mutations Index of human polymorphisms and disease mutations |
| SIMILARITY comments Index of protein domains and families |

Clusters with


