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Q9H4N9

- Q9H4N9_HUMAN

UniProt

Q9H4N9 - Q9H4N9_HUMAN

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Protein
Submitted name:

Clone CDABP0042 mRNA sequence

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA helicase activity Source: Ensembl
  3. single-stranded DNA binding Source: Ensembl

GO - Biological processi

  1. cell proliferation Source: Ensembl
  2. cellular response to epidermal growth factor stimulus Source: Ensembl
  3. DNA replication initiation Source: InterPro
  4. DNA unwinding involved in DNA replication Source: Ensembl
  5. response to drug Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, DNA-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Clone CDABP0042 mRNA sequenceImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. MCM complex Source: InterPro
  3. nucleus Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9H4N9.

Expressioni

Gene expression databases

BgeeiQ9H4N9.
ExpressionAtlasiQ9H4N9. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-1447717.

Structurei

3D structure databases

ProteinModelPortaliQ9H4N9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MCM family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR008050. MCM7.
IPR018525. MCM_CS.
IPR001208. MCM_DNA-dep_ATPase.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11630:SF26. PTHR11630:SF26. 1 hit.
PfamiPF00493. MCM. 1 hit.
[Graphical view]
PRINTSiPR01657. MCMFAMILY.
SMARTiSM00382. AAA. 1 hit.
SM00350. MCM. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H4N9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIRGNINIC LMGDPGVAKS QLLSYIDRLA PRSQYTTGRG SSGVGLTAAV
60 70 80 90 100
LRDSVSGELT LEGGALVLAD QGVCCIDEFD KMAEADRTAI HEVMEQQTIS
110 120 130 140 150
IAKAGILTTL NARCSILAAA NPAYGRYNPR RSLEQNIQLP AALLSRFDLL
160 170 180 190 200
WLIQDRPDRD NDLRLAQHIT YVHQHSRQPP SQFEPLDMKL MRRYIAMCRE
210 220 230 240 250
KQPMVPESLA DYITAAYVEM RREAWASKDA TYTSARTLLA ILRLSTALAR
260 270 280 290 300
LRMVDVVEKE DVNEAIRLME MSKDSLLGDK GQTARTQRPA DVIFATVREL
310 320 330 340 350
VSGGRSVRFS EAEQRCVSRG FTPAQFQAAL DEYEELNVWQ VNASRTRITF

V
Length:351
Mass (Da):39,244
Last modified:March 1, 2001 - v1
Checksum:iA98BCFB9922E80F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007130 mRNA. Translation: AAG01994.1.
UniGeneiHs.438720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007130 mRNA. Translation: AAG01994.1 .
UniGenei Hs.438720.

3D structure databases

ProteinModelPortali Q9H4N9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1447717.

Proteomic databases

PRIDEi Q9H4N9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q9H4N9.
ExpressionAtlasi Q9H4N9. baseline and differential.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR008050. MCM7.
IPR018525. MCM_CS.
IPR001208. MCM_DNA-dep_ATPase.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR11630:SF26. PTHR11630:SF26. 1 hit.
Pfami PF00493. MCM. 1 hit.
[Graphical view ]
PRINTSi PR01657. MCMFAMILY.
SMARTi SM00382. AAA. 1 hit.
SM00350. MCM. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A "double adaptor" method for improved shotgun library construction."
    Andersson B., Wentland M.A., Ricafrente J.Y., Liu W., Gibbs R.A.
    Anal. Biochem. 236:107-113(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Large-scale concatenation cDNA sequencing."
    Yu W., Andersson B., Worley K.C., Muzny D.M., Ding Y., Liu W., Ricafrente J.Y., Wentland M.A., Lennon G., Gibbs R.A.
    Genome Res. 7:353-358(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Zhou J., Yu W., Tang H., Mei G., Tsang Y.T.M., Bouck J., Gibbs R.A., Margolin J.F.
    Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9H4N9_HUMAN
AccessioniPrimary (citable) accession number: Q9H4N9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.