Q9H4N9 (Q9H4N9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Clone CDABP0042 mRNA sequence EMBL AAG01994.1
Organism	Homo sapiens (Human) EMBL AAG01994.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the MCM family. RuleBase RU004070 Contains 1 MCM domain. SAAS SAAS018525

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS001208
Ligand	ATP-binding RuleBase RU004070 SAAS SAAS018525 DNA-binding RuleBase RU004070 SAAS SAAS018525 Nucleotide-binding
Gene Ontology (GO)
Biological_process	DNA replication initiation Inferred from electronic annotation. Source: InterPro DNA unwinding involved in replication Inferred from electronic annotation. Source: Compara cell proliferation Inferred from electronic annotation. Source: Compara cellular response to epidermal growth factor stimulus Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara
Cellular_component	MCM complex Inferred from electronic annotation. Source: InterPro cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA helicase activity Inferred from electronic annotation. Source: Compara single-stranded DNA binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9H4N9 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: A98BCFB9922E80F5	FASTA	351	39,244
	10 20 30 40 50 60 MKIRGNINIC LMGDPGVAKS QLLSYIDRLA PRSQYTTGRG SSGVGLTAAV LRDSVSGELT 70 80 90 100 110 120 LEGGALVLAD QGVCCIDEFD KMAEADRTAI HEVMEQQTIS IAKAGILTTL NARCSILAAA 130 140 150 160 170 180 NPAYGRYNPR RSLEQNIQLP AALLSRFDLL WLIQDRPDRD NDLRLAQHIT YVHQHSRQPP 190 200 210 220 230 240 SQFEPLDMKL MRRYIAMCRE KQPMVPESLA DYITAAYVEM RREAWASKDA TYTSARTLLA 250 260 270 280 290 300 ILRLSTALAR LRMVDVVEKE DVNEAIRLME MSKDSLLGDK GQTARTQRPA DVIFATVREL 310 320 330 340 350 VSGGRSVRFS EAEQRCVSRG FTPAQFQAAL DEYEELNVWQ VNASRTRITF V

References

[1]	"A "double adaptor" method for improved shotgun library construction." Andersson B., Wentland M.A., Ricafrente J.Y., Liu W., Gibbs R.A. Anal. Biochem. 236:107-113(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Large-scale concatenation cDNA sequencing." Yu W., Andersson B., Worley K.C., Muzny D.M., Ding Y., Liu W., Ricafrente J.Y., Wentland M.A., Lennon G., Gibbs R.A. Genome Res. 7:353-358(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Zhou J., Yu W., Tang H., Mei G., Tsang Y.T.M., Bouck J., Gibbs R.A., Margolin J.F. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY007130 mRNA. Translation: AAG01994.1.
IPI	IPI00376143.
UniGene	Hs.438720.
3D structure databases
ProteinModelPortal	Q9H4N9.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1447717.
STRING	Q9H4N9.
Proteomic databases
PRIDE	Q9H4N9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q9H4N9.
Bgee	Q9H4N9.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR008050. MCM7. IPR018525. MCM_CS. IPR001208. MCM_DNA-dep_ATPase. [Graphical view]
PANTHER	PTHR11630:SF26. PTHR11630:SF26. 1 hit.
Pfam	PF00493. MCM. 1 hit. [Graphical view]
PRINTS	PR01657. MCMFAMILY.
SMART	SM00382. AAA. 1 hit. SM00350. MCM. 1 hit. [Graphical view]
PROSITE	PS00847. MCM_1. 1 hit. PS50051. MCM_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9H4N9_HUMAN

Accession

Primary (citable) accession number: Q9H4N9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.