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Protein
Submitted name:

Breast and ovarian cancer susceptibility protein 2

Gene

BRCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Breast and ovarian cancer susceptibility protein 2Imported
Submitted name:
Breast cancer 2 tumor suppressorImported
Gene namesi
Name:BRCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiENSG00000139618.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369497.

Structurei

3D structure databases

ProteinModelPortaliQ9H4L3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 56BRCA-2_helicalInterPro annotationAdd BLAST56

Phylogenomic databases

eggNOGiKOG4751. Eukaryota.
ENOG410Y06W. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR015525. BRCA2.
IPR015252. BRCA2_hlx.
PANTHERiPTHR11289. PTHR11289. 1 hit.
PfamiView protein in Pfam
PF09169. BRCA-2_helical. 1 hit.
SUPFAMiSSF81872. SSF81872. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9H4L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALCDTPGVDP KLISRIWVYN HYRWIIWKLA AMECAFPKEF ANRCLSPERV

LLQLKY
Length:56
Mass (Da):6,668
Last modified:March 1, 2001 - v1
Checksum:i72A1D919AC358716
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei56Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY008850 Genomic DNA. Translation: AAG32681.1.
DQ889340 Genomic DNA. Translation: ABJ90481.1.
UniGeneiHs.34012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY008850 Genomic DNA. Translation: AAG32681.1.
DQ889340 Genomic DNA. Translation: ABJ90481.1.
UniGeneiHs.34012.

3D structure databases

ProteinModelPortaliQ9H4L3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369497.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4751. Eukaryota.
ENOG410Y06W. LUCA.

Gene expression databases

BgeeiENSG00000139618.

Family and domain databases

InterProiView protein in InterPro
IPR015525. BRCA2.
IPR015252. BRCA2_hlx.
PANTHERiPTHR11289. PTHR11289. 1 hit.
PfamiView protein in Pfam
PF09169. BRCA-2_helical. 1 hit.
SUPFAMiSSF81872. SSF81872. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9H4L3_HUMAN
AccessioniPrimary (citable) accession number: Q9H4L3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.