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Protein

RIB43A-like with coiled-coils protein 2

Gene

RIBC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
RIB43A-like with coiled-coils protein 2
Gene namesi
Name:RIBC2
Synonyms:C22orf11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:13241. RIBC2.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134967342.

Polymorphism and mutation databases

DMDMi74752644.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309RIB43A-like with coiled-coils protein 2PRO_0000254098Add
BLAST

Proteomic databases

PaxDbiQ9H4K1.
PeptideAtlasiQ9H4K1.
PRIDEiQ9H4K1.

PTM databases

iPTMnetiQ9H4K1.
PhosphoSiteiQ9H4K1.

Expressioni

Gene expression databases

BgeeiENSG00000128408.
CleanExiHS_RIBC2.

Organism-specific databases

HPAiHPA003210.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
taxP140793EBI-740128,EBI-9675698From a different organism.

Protein-protein interaction databases

BioGridi117581. 24 interactions.
IntActiQ9H4K1. 26 interactions.
STRINGi9606.ENSP00000444196.

Structurei

3D structure databases

ProteinModelPortaliQ9H4K1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili149 – 18234Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the RIB43A family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IE6I. Eukaryota.
ENOG410YKAG. LUCA.
HOGENOMiHOG000231390.
HOVERGENiHBG056758.
InParanoidiQ9H4K1.
PhylomeDBiQ9H4K1.

Family and domain databases

InterProiIPR008805. RIB43A.
[Graphical view]
PANTHERiPTHR14517. PTHR14517. 1 hit.
PfamiPF05914. RIB43A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H4K1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQNDKIMCI LENRKKRDRK NLCRAINDFQ QSFQKPETRR EFDLSDPLAL
60 70 80 90 100
KKDLPARQSD NDVRNTISGM QKFMGEDLNF HERKKFQEEQ NREWSLQQQR
110 120 130 140 150
EWKNARAEQK CAEALYTETR LQFDETAKHL QKLESTTRKA VCASVKDFNK
160 170 180 190 200
SQAIESVERK KQEKKQEQED NLAEITNLLR GDLLSENPQQ AASSFGPHRV
210 220 230 240 250
VPDRWKGMTQ EQLEQIRLVQ KQQIQEKLRL QEEKRQRDLD WDRRRIQGAR
260 270 280 290 300
ATLLFERQQW RRQRDLRRAL DSSNLSLAKE QHLQKKYMNE VYTNQPTGDY

FTQFNTGSR
Length:309
Mass (Da):37,060
Last modified:March 1, 2001 - v1
Checksum:iAD7EB2293C8027AF
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti180 – 1801R → C.
Corresponds to variant rs2142661 [ dbSNP | Ensembl ].
VAR_028812
Natural varianti195 – 1951F → L.2 Publications
Corresponds to variant rs1022478 [ dbSNP | Ensembl ].
VAR_028813
Natural varianti262 – 2621R → Q.2 Publications
Corresponds to variant rs2072770 [ dbSNP | Ensembl ].
VAR_028814

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR457398 mRNA. Translation: CAG33679.1.
AL442116 mRNA. Translation: CAC09526.1.
CR456438 mRNA. Translation: CAG30324.1.
AL021391 Genomic DNA. No translation available.
BC003024 mRNA. Translation: AAH03024.1.
BC009904 mRNA. Translation: AAH09904.1.
AL050075 mRNA. Translation: CAB43258.1.
PIRiT08734.
RefSeqiNP_056468.3. NM_015653.4.
XP_005261581.1. XM_005261524.4.
UniGeneiHs.475110.

Genome annotation databases

EnsembliENST00000342894; ENSP00000342529; ENSG00000128408.
GeneIDi26150.
KEGGihsa:26150.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR457398 mRNA. Translation: CAG33679.1.
AL442116 mRNA. Translation: CAC09526.1.
CR456438 mRNA. Translation: CAG30324.1.
AL021391 Genomic DNA. No translation available.
BC003024 mRNA. Translation: AAH03024.1.
BC009904 mRNA. Translation: AAH09904.1.
AL050075 mRNA. Translation: CAB43258.1.
PIRiT08734.
RefSeqiNP_056468.3. NM_015653.4.
XP_005261581.1. XM_005261524.4.
UniGeneiHs.475110.

3D structure databases

ProteinModelPortaliQ9H4K1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117581. 24 interactions.
IntActiQ9H4K1. 26 interactions.
STRINGi9606.ENSP00000444196.

PTM databases

iPTMnetiQ9H4K1.
PhosphoSiteiQ9H4K1.

Polymorphism and mutation databases

DMDMi74752644.

Proteomic databases

PaxDbiQ9H4K1.
PeptideAtlasiQ9H4K1.
PRIDEiQ9H4K1.

Protocols and materials databases

DNASUi26150.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000342894; ENSP00000342529; ENSG00000128408.
GeneIDi26150.
KEGGihsa:26150.

Organism-specific databases

CTDi26150.
GeneCardsiRIBC2.
HGNCiHGNC:13241. RIBC2.
HPAiHPA003210.
neXtProtiNX_Q9H4K1.
PharmGKBiPA134967342.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IE6I. Eukaryota.
ENOG410YKAG. LUCA.
HOGENOMiHOG000231390.
HOVERGENiHBG056758.
InParanoidiQ9H4K1.
PhylomeDBiQ9H4K1.

Miscellaneous databases

GenomeRNAii26150.
PROiQ9H4K1.

Gene expression databases

BgeeiENSG00000128408.
CleanExiHS_RIBC2.

Family and domain databases

InterProiIPR008805. RIB43A.
[Graphical view]
PANTHERiPTHR14517. PTHR14517. 1 hit.
PfamiPF05914. RIB43A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRIBC2_HUMAN
AccessioniPrimary (citable) accession number: Q9H4K1
Secondary accession number(s): Q6ICD0, Q9Y413
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.