Q9H4I9 (CV032_HUMAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: UPF0466 protein C22orf32, mitochondrial | ||
| Gene names |
| ||
| Organism | Homo sapiens (Human) [Reference proteome] | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo![]() |
Protein attributes
| Sequence length | 107 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Subcellular location | Mitochondrion Potential. Membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Belongs to the UPF0466 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane Mitochondrion |
| Coding sequence diversity | Polymorphism |
| Domain | Transit peptide Transmembrane Transmembrane helix |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrionInferred from electronic annotation. Source: UniProtKB-SubCell |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transit peptide | 1 – 47 | 47 | Mitochondrion Potential | ||||||
| Chain | 48 – 107 | 60 | UPF0466 protein C22orf32, mitochondrial | PRO_0000296320 | |||||
Regions | |||||||||
| Transmembrane | 65 – 84 | 20 | Helical; Potential | ||||||
| Compositional bias | 93 – 107 | 15 | Asp/Glu-rich | ||||||
Natural variations | |||||||||
| Natural variant | 46 | 1 | R → G. Ref.5 Corresponds to variant rs17852210 [ dbSNP | Ensembl ]. | VAR_034628 | |||||
Sequences
References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AL449243 mRNA. Translation: CAC15000.1. CR456453 mRNA. Translation: CAG30339.1. AK312142 mRNA. Translation: BAG35078.1. Z82192, AL021878 Genomic DNA. Translation: CAI19711.1. CH471095 Genomic DNA. Translation: EAW60488.1. BC024237 mRNA. Translation: AAH24237.1. |
| IPI | IPI00154512. |
| RefSeq | NP_201575.3. NM_033318.4. |
| UniGene | Hs.306083. |
3D structure databases | |
| ProteinModelPortal | Q9H4I9. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 9606.ENSP00000327467. |
Polymorphism databases | |
| DMDM | 74761431. |
Proteomic databases | |
| PaxDb | Q9H4I9. |
| PRIDE | Q9H4I9. |
Protocols and materials databases | |
| DNASU | 91689. |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENST00000331479; ENSP00000327467; ENSG00000183172. ENST00000571525; ENSP00000459368; ENSG00000262254. |
| GeneID | 91689. |
| KEGG | hsa:91689. |
| UCSC | uc003bca.3. human. |
Organism-specific databases | |
| CTD | 91689. |
| GeneCards | GC22P042475. |
| H-InvDB | HIX0019152. |
| HGNC | HGNC:25055. C22orf32. |
| HPA | HPA032117. |
| neXtProt | NX_Q9H4I9. |
| PharmGKB | PA145149451. |
| GenAtlas | Search... |
Phylogenomic databases | |
| eggNOG | NOG282161. |
| HOGENOM | HOG000018296. |
| HOVERGEN | HBG095170. |
| InParanoid | Q9H4I9. |
| OMA | GPSLRKD. |
| PhylomeDB | Q9H4I9. |
Gene expression databases | |
| ArrayExpress | Q9H4I9. |
| Bgee | Q9H4I9. |
| CleanEx | HS_C22orf32. |
| Genevestigator | Q9H4I9. |
Family and domain databases | |
| InterPro | IPR018782. UPF0466. [Graphical view] |
| Pfam | PF10161. DDDD. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| GenomeRNAi | 91689. |
| NextBio | 77399. |
Entry information
| Entry name | CV032_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q9H4I9 Secondary accession number(s): B2R5D1, Q8TAB9 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Uncharacterized protein families (UPF) List of uncharacterized protein family (UPF) entries |
| Human chromosome 22 Human chromosome 22: entries, gene names and cross-references to MIM |
| Human entries with polymorphisms or disease mutations List of human entries with polymorphisms or disease mutations |
| Human polymorphisms and disease mutations Index of human polymorphisms and disease mutations |
| SIMILARITY comments Index of protein domains and families |

Clusters with
