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Protein
Submitted name:

Protein kinase

Gene

dik

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB
  • protein serine/threonine kinase activity Source: UniProtKB

GO - Biological processi

  • protein phosphorylation Source: UniProtKB

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

SignaLinkiQ9H4D1

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinaseImported
Gene namesi
Name:dikImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24805

Expressioni

Gene expression databases

GenevisibleiQ9H4D1 HS

Structurei

3D structure databases

ProteinModelPortaliQ9H4D1
SMRiQ9H4D1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 286Protein kinaseInterPro annotationAdd BLAST265
Domaini437 – 766ANK_REP_REGIONInterPro annotationAdd BLAST330
Repeati437 – 469ANKPROSITE-ProRule annotationAdd BLAST33
Repeati470 – 502ANKPROSITE-ProRule annotationAdd BLAST33
Repeati503 – 535ANKPROSITE-ProRule annotationAdd BLAST33
Repeati536 – 568ANKPROSITE-ProRule annotationAdd BLAST33
Repeati603 – 635ANKPROSITE-ProRule annotationAdd BLAST33
Repeati636 – 668ANKPROSITE-ProRule annotationAdd BLAST33
Repeati669 – 701ANKPROSITE-ProRule annotationAdd BLAST33
Repeati702 – 724ANKPROSITE-ProRule annotationAdd BLAST23
Repeati734 – 766ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0192 Eukaryota
KOG0504 Eukaryota
COG0515 LUCA
COG0666 LUCA
HOVERGENiHBG061582
KOiK08848

Family and domain databases

CDDicd00204 ANK, 4 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF12796 Ank_2, 3 hits
PF00069 Pkinase, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 10 hits
SM00220 S_TKc, 1 hit
SUPFAMiSSF48403 SSF48403, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 9 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q9H4D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGDGGTPWA LALLRTFDAG EFTGWEKVGS GGFGQVYKVR HVHWKTWLAI
60 70 80 90 100
KCSPSLHVDD RERMELLEEA KKMEMAKFRY ILPVYGICRE PVGLVMEYME
110 120 130 140 150
TGSLEKLLAS EPLPWDLRFR IIHETAVGMN FLHCMAPPLL HLDLKPANIL
160 170 180 190 200
LDAHYHVKIS DFGLAKCNGL SHSHDLSMDG LFGTIAYLPP ERIREKSRLF
210 220 230 240 250
DTKHDVYSFA IVIWGVLTQK KPFADEKNIL HIMVKVVKGH RPELPPVCRA
260 270 280 290 300
RPRACSHLIR LMQRCWQGDP RVRPTFQEIT SETEDLCEKP DDEVKETAHD
310 320 330 340 350
LDVKSPPEPR SEVVPARLKR ASAPTFDNDY SLSELLSQLD SGVSQAVEGP
360 370 380 390 400
EELSRSSSES KLPSSGSGKR LSGVSSVDSA FSSRGSLSLS FEREPSTSDL
410 420 430 440 450
GTTDVQKKKL VDAIVSGDTS KLMKILQPQD VDLALDSGAS LLHLAVEAGQ
460 470 480 490 500
EECAKWLLLN NANPNLSNRR GSTPLHMAVE RRVRGVVELL LARKISVNAK
510 520 530 540 550
DEDQWTALHF AAQNGDESST RLLLEKNASV NEVDFEGRTP MHVACQHGQE
560 570 580 590 600
NIVRILLRRG VDVSLQGKDA WLPLHYAAWQ GHLPIVKLLA KQPGVSVNAQ
610 620 630 640 650
TLDGRTPLHL AAQRGHYRVA RILIDLCSDV NVCSLLAQTP LHVAAETGHT
660 670 680 690 700
STARLLLHRG AGKKAVTSDG YTALHLAARN GHLATVKLLV EEKADVLARG
710 720 730 740 750
PLNQTALHLA AAHGHSEVVE ELVSADVIDL FDEQGLSALH LAAQGRHAQT
760 770 780
VETLLRHGAH INLQSLKFQG GHGPAATLLR RSKT
Length:784
Mass (Da):86,408
Last modified:March 1, 2001 - v1
Checksum:iF3C7D5D52A35AF91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ278016 mRNA Translation: CAC04247.1
RefSeqiNP_065690.2, NM_020639.2
UniGeneiHs.517310

Genome annotation databases

GeneIDi54101
KEGGihsa:54101

Similar proteinsi

Entry informationi

Entry nameiQ9H4D1_HUMAN
AccessioniPrimary (citable) accession number: Q9H4D1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: April 25, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health