Reviewed, UniProtKB/Swiss-Prot Q9H3Z7 (CT135_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C20orf135

Gene names

Name:

C20orf135

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the BAT5 family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 469	469	Uncharacterized protein C20orf135		PRO_0000079463
Regions
	Compositional bias	53 – 57	5	Poly-Ala
	Compositional bias	433 – 437	5	Poly-Arg
Natural variations
	Natural variant	10	1	L → Q: dbSNP rs2281534.		VAR_050920

Sequences

	Sequence		Length	Mass (Da)
	Q9H3Z7-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 85C72E84CCFFC9A1	FASTA	469	52,555
	10 20 30 40 50 60 MCVICFVKAL VRVFKIYLTA SYTYPFRGWP VAFRWDDVRA VGRSSSHRAL TCAAAAAGVW 70 80 90 100 110 120 LLRDETLGGD ALGRPPRGAR SQAQCLLQQL RELPGQLASY ALAHSLGRWL VYPGSVSLMT 130 140 150 160 170 180 RALLPLLQQG QERLVERYHG RRAKLVACDG NEIDTMFMDR RQHPGSHVHG PRLVICCEGN 190 200 210 220 230 240 AGFYEMGCLS APLEAGYSVL GWNHPGFGSS TGVPFPQHDA NAMDVVVEYA LHRLHFPPAH 250 260 270 280 290 300 LVVYGWSVGG FTATWATMTY PELGALVLDA TFDDLVPLAL KVMPHSWKGL VVRTVREHFN 310 320 330 340 350 360 LNVAEQLCCY PGPVLLLRRT QDDVVSTSGR LRPLSPGDVE GNRGNELLLR LLEHRYPVVM 370 380 390 400 410 420 AREGRAVVTR WLRAGSLAQE AAFYARYRVD EDWCLALLRS YRARCEEELE GEEALGPHGP 430 440 450 460 AFPWLVGQGL SSRRRRRLAL FLARKHLKNV EATHFSPLEP EEFQLPWRL

References

[1]

"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL118506 Genomic DNA. Translation: CAC15491.1.
IPI	IPI00168410.
RefSeq	NP_542189.1.
UniGene	Hs.266774 Hs.675171
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	S09.976.
PTM databases
PhosphoSite	Q9H3Z7.
Proteomic databases
PRIDE	Q9H3Z7.
Genome annotation databases
Ensembl	ENST00000369916; ENSP00000358932; ENSG00000183260; Homo sapiens. [Genome view]
GeneID	140701.
KEGG	hsa:140701.
UCSC	uc002ygx.1. human.
Organism-specific databases
CTD	140701.
GeneCards	GC20P061963.
HGNC	HGNC:16128. C20orf135.
PharmGKB	PA25677.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HBG444395.
HOVERGEN	Q9H3Z7.
InParanoid	Q9H3Z7.
OMA	SHRALTC.
OrthoDB	EOG9Q87H5.
Gene expression databases
ArrayExpress	Q9H3Z7.
Bgee	Q9H3Z7.
CleanEx	HS_C20orf135.
Genevestigator	Q9H3Z7.
GermOnline	ENSG00000183260. Homo sapiens.
Family and domain databases
InterPro	IPR000073. AB_hydrolase_1. [Graphical view]
Pfam	PF00561. Abhydrolase_1. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	84271.

Entry information

Entry name

CT135_HUMAN

Accession

Primary (citable) accession number: Q9H3Z7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	March 1, 2001
Last modified:	December 15, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.