Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9H3X6

- Q9H3X6_HUMAN

UniProt

Q9H3X6 - Q9H3X6_HUMAN

Protein
Submitted name:

T200 leukocyte common antigen

Gene

PTPRC

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. heparin binding Source: Ensembl

    GO - Biological processi

    1. activation of MAPK activity Source: Ensembl
    2. B cell differentiation Source: Ensembl
    3. B cell proliferation Source: Ensembl
    4. B cell receptor signaling pathway Source: Ensembl
    5. defense response to virus Source: Ensembl
    6. heterotypic cell-cell adhesion Source: Ensembl
    7. leukocyte cell-cell adhesion Source: Ensembl
    8. negative regulation of cytokine-mediated signaling pathway Source: Ensembl
    9. negative regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
    10. negative regulation of protein autophosphorylation Source: Ensembl
    11. negative regulation of T cell mediated cytotoxicity Source: Ensembl
    12. negative thymic T cell selection Source: Ensembl
    13. positive regulation of alpha-beta T cell proliferation Source: Ensembl
    14. positive regulation of antigen receptor-mediated signaling pathway Source: Ensembl
    15. positive regulation of B cell proliferation Source: Ensembl
    16. positive regulation of extrinsic apoptotic signaling pathway Source: Ensembl
    17. positive regulation of gamma-delta T cell differentiation Source: Ensembl
    18. positive regulation of humoral immune response mediated by circulating immunoglobulin Source: Ensembl
    19. positive regulation of isotype switching to IgG isotypes Source: Ensembl
    20. positive regulation of T cell mediated cytotoxicity Source: Ensembl
    21. positive thymic T cell selection Source: Ensembl
    22. protein dephosphorylation Source: Ensembl
    23. regulation of B cell differentiation Source: Ensembl
    24. regulation of B cell receptor signaling pathway Source: Ensembl
    25. regulation of cell cycle Source: Ensembl
    26. release of sequestered calcium ion into cytosol Source: Ensembl
    27. response to gamma radiation Source: Ensembl
    28. T cell proliferation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    T200 leukocyte common antigenImported
    Gene namesi
    Name:PTPRCImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: Ensembl
    2. focal adhesion Source: Ensembl
    3. integral component of plasma membrane Source: Ensembl

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini32 – ›34›3T200 leukocyte common antigenImportedPRO_5000143176

    Expressioni

    Gene expression databases

    ArrayExpressiQ9H3X6.
    BgeeiQ9H3X6.

    Family & Domainsi

    Family and domain databases

    InterProiIPR024739. PTP_recept_N.
    [Graphical view]
    PfamiPF12453. PTP_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9H3X6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYLWLKLLAF GFAFLDTEVF VTGQSPTPSP TGLT                    34
    Length:34
    Mass (Da):3,749
    Last modified:March 1, 2001 - v1
    Checksum:i0C261F8943734758
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei34 – 341Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M23463, M23461, M23462 Genomic DNA. Translation: AAG26082.1.
    UniGeneiHs.654514.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M23463 , M23461 , M23462 Genomic DNA. Translation: AAG26082.1 .
    UniGenei Hs.654514.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi PTPRC. human.

    Gene expression databases

    ArrayExpressi Q9H3X6.
    Bgeei Q9H3X6.

    Family and domain databases

    InterProi IPR024739. PTP_recept_N.
    [Graphical view ]
    Pfami PF12453. PTP_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete exon-intron organization of the human leukocyte common antigen (CD45) gene."
      Hall L.R., Streuli M., Schlossman S.F., Saito H.
      J. Immunol. 141:2781-2787(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PlacentaImported.

    Entry informationi

    Entry nameiQ9H3X6_HUMAN
    AccessioniPrimary (citable) accession number: Q9H3X6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.