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Protein
Submitted name:

Fibulin-like extracellular matrix protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fibulin-like extracellular matrix proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 443416Sequence analysisPRO_5004327935Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ9H3D5.
PRIDEiQ9H3D5.

Expressioni

Gene expression databases

GenevisibleiQ9H3D5. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000309953.

Structurei

3D structure databases

ProteinModelPortaliQ9H3D5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini123 – 16341EGF-likeInterPro annotationAdd
BLAST
Domaini164 – 20239EGF-likeInterPro annotationAdd
BLAST
Domaini203 – 23836EGF-likeInterPro annotationAdd
BLAST
Domaini243 – 28240EGF-likeInterPro annotationAdd
BLAST

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IR6U. Eukaryota.
ENOG410ZNNG. LUCA.
HOVERGENiHBG051560.
KOiK19866.

Family and domain databases

InterProiIPR026823. cEGF.
IPR026824. Efemp2.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
[Graphical view]
PANTHERiPTHR24044:SF327. PTHR24044:SF327. 2 hits.
PfamiPF12662. cEGF. 2 hits.
PF07645. EGF_CA. 3 hits.
[Graphical view]
SMARTiSM00181. EGF. 5 hits.
SM00179. EGF_CA. 6 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 2 hits.
PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H3D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPCASCLPG SLLLWALLLL LLGSASPQDS EEPDSYTECT DGYEWDPDSQ
60 70 80 90 100
HCRDVNECLT IPEACKGEMK CINHYGGYLC LPRSAAVIND LHGEGPPPPV
110 120 130 140 150
PPAQHPNPCP PGYEPDDQDS CVDVDECAQA LHDRRPSQDC HNLSGSYQCT
160 170 180 190 200
CPDGYRKIGP ECVDIDECRY RYCQHRCVNL PGSFRCQCEP GFQLGPNNRS
210 220 230 240 250
CVDVNECDMG APCEQRCFNS YGTFLCRCHQ GYELHRDGFS CSDIDECSYS
260 270 280 290 300
SYLCQYRCVN EPGRFSCHCP QGYQLLATRL CQDIDECESG AHQCSEAQTC
310 320 330 340 350
VNFHGGYRCV DTNRCVEPYI QVSENRCLCP ASNPLCREQP SSIVHRYMTI
360 370 380 390 400
TSERMRPADV FQIQATSVYP GAYNAFQIRA GNSQGDFYIR QINNVSAMLV
410 420 430 440
LARPVTGPRE YVLDLEMVTM NSLMSYRASS VLRLTVFVGA YTF
Length:443
Mass (Da):49,536
Last modified:March 1, 2001 - v1
Checksum:iD91784BF36A8A060
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF124486 mRNA. Translation: AAG45245.1.
RefSeqiNP_058634.4. NM_016938.4.
UniGeneiHs.731454.

Genome annotation databases

GeneIDi30008.
KEGGihsa:30008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF124486 mRNA. Translation: AAG45245.1.
RefSeqiNP_058634.4. NM_016938.4.
UniGeneiHs.731454.

3D structure databases

ProteinModelPortaliQ9H3D5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000309953.

Proteomic databases

PaxDbiQ9H3D5.
PRIDEiQ9H3D5.

Protocols and materials databases

DNASUi30008.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30008.
KEGGihsa:30008.

Organism-specific databases

CTDi30008.

Phylogenomic databases

eggNOGiENOG410IR6U. Eukaryota.
ENOG410ZNNG. LUCA.
HOVERGENiHBG051560.
KOiK19866.

Miscellaneous databases

GenomeRNAii30008.
NextBioi52820.

Gene expression databases

GenevisibleiQ9H3D5. HS.

Family and domain databases

InterProiIPR026823. cEGF.
IPR026824. Efemp2.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
[Graphical view]
PANTHERiPTHR24044:SF327. PTHR24044:SF327. 2 hits.
PfamiPF12662. cEGF. 2 hits.
PF07645. EGF_CA. 3 hits.
[Graphical view]
SMARTiSM00181. EGF. 5 hits.
SM00179. EGF_CA. 6 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 2 hits.
PROSITEiPS00010. ASX_HYDROXYL. 4 hits.
PS01186. EGF_2. 4 hits.
PS50026. EGF_3. 4 hits.
PS01187. EGF_CA. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of a new fibulin-like gene."
    Seibold S., Marx M.
    Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9H3D5_HUMAN
AccessioniPrimary (citable) accession number: Q9H3D5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 11, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.