ID   Q9H317_HUMAN            Unreviewed;       303 AA.
AC   Q9H317;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Tight junction protein ZO-1 {ECO:0000313|EMBL:AAG43399.1};
DE   Flags: Fragment;
GN   Name=TJP1 {ECO:0000313|EMBL:AAG43399.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAG43399.1};
RN   [1] {ECO:0000313|EMBL:AAG43399.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Martinez-Contreras R.D., Galindo J.M., Valdes J.;
RT   "Three exonic elements regulate the alternative splicing of the alpha exon
RT   of ZO-1 pre-mRNA.";
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AF169196; AAG43399.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9H317; -.
DR   ChiTaRS; TJP1; human.
DR   PANTHER; PTHR13865; TIGHT JUNCTION PROTEIN; 1.
DR   PANTHER; PTHR13865:SF25; TIGHT JUNCTION PROTEIN ZO-1; 1.
PE   4: Predicted;
FT   REGION          1..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..228
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAG43399.1"
FT   NON_TER         303
FT                   /evidence="ECO:0000313|EMBL:AAG43399.1"
SQ   SEQUENCE   303 AA;  34897 MW;  A382B5A29EF50D01 CRC64;
     EDTDTEGGAY TDQELDETLN DEVGTPPESA ITRSSEPVRE DSSGMHHENQ TYPPYSPQAH
     AQPIHRIDSP GFKPASQQKA EASSPVPYLS PETNPASSTS AVNHNVNLTN VRLEEPTPAP
     SPSYSPQADS LRTPSTEAAH IMLRDQEPSL SSHVDPTKVY RKDPYPEEMM RQNHVLKQPA
     VSHPGHRPDK EPNLTYEPQL PYVEKQASRD LEQPTYRYES SSYTDQFSRN YEHRLRYEDR
     VPMYEEQWSY YDDKQPYPSR PPFDNQRSQD LDSRQHPEES SERGYFPRFE EPAPRSYDSR
     PRY
//