Q9H2V7 (SPNS1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein spinster homolog 1

Alternative name(s):
HSpin1
Spinster-like protein 1

Gene names

Name:	SPNS1
Synonyms:	SPIN1
ORF Names:	PP20300

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	528 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Sphingolipid transporter By similarity. May be involved in necrotic or autophagic cell death. Ref.8
Subunit structure	Interacts with BCL2 and BCL2L1. Ref.8
Subcellular location	Mitochondrion inner membrane; Multi-pass membrane protein. Note: Colocalizes with SDHB. Ref.8
Sequence similarities	Belongs to the major facilitator (TC 2.A.1) superfamily. Spinster (TC 2.A.1.49) family. [View classification]
Sequence caution	The sequence AAQ15259.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence AAQ15259.1 differs from that shown. Reason: Frameshift at position 97.

Ontologies

Keywords
Biological process	Lipid transport Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	lipid transport Inferred from electronic annotation. Source: UniProtKB-KW transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
BCL2L1	Q07817	3	EBI-1386527,EBI-78035

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9H2V7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9H2V7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     271-322: Missing.

Isoform 3 (identifier: Q9H2V7-3)

Also known as: CRA_d;

The sequence of this isoform differs from the canonical sequence as follows:
     81-102: Missing.
     271-322: Missing.

Isoform 4 (identifier: Q9H2V7-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-73: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q9H2V7-5)

The sequence of this isoform differs from the canonical sequence as follows:
     223-528: TPGLGVVAVL...TRVPVASVLI → SLVLAWG

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 528	528	Protein spinster homolog 1		PRO_0000305039
Regions
	Transmembrane	50 – 70	21	Helical; Potential
	Transmembrane	98 – 118	21	Helical; Potential
	Transmembrane	127 – 147	21	Helical; Potential
	Transmembrane	160 – 180	21	Helical; Potential
	Transmembrane	187 – 207	21	Helical; Potential
	Transmembrane	218 – 238	21	Helical; Potential
	Transmembrane	278 – 298	21	Helical; Potential
	Transmembrane	323 – 343	21	Helical; Potential
	Transmembrane	357 – 377	21	Helical; Potential
	Transmembrane	381 – 401	21	Helical; Potential
	Transmembrane	421 – 441	21	Helical; Potential
	Transmembrane	465 – 485	21	Helical; Potential
Amino acid modifications
	Modified residue	518	1	Phosphoserine Ref.9
Natural variations
	Alternative sequence	1 – 73	73	Missing in isoform 4.		VSP_028194
	Alternative sequence	81 – 102	22	Missing in isoform 3.		VSP_028195
	Alternative sequence	223 – 528	306	TPGLG…ASVLI → SLVLAWG in isoform 5.		VSP_036389
	Alternative sequence	271 – 322	52	Missing in isoform 2 and isoform 3.		VSP_028196
	Natural variant	230	1	A → P. Ref.7 Corresponds to variant rs17855956 [ dbSNP | Ensembl ].		VAR_035157

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: F1B9D2EB3F9F1B48	FASTA	528	56,630
	10 20 30 40 50 60 MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRSAL 70 80 90 100 110 120 IVAVLCYINL LNYMDRFTVA GVLPDIEQFF NIGDSSSGLI QTVFISSYMV LAPVFGYLGD 130 140 150 160 170 180 RYNRKYLMCG GIAFWSLVTL GSSFIPGEHF WLLLLTRGLV GVGEASYSTI APTLIADLFV 190 200 210 220 230 240 ADQRSRMLSI FYFAIPVGSG LGYIAGSKVK DMAGDWHWAL RVTPGLGVVA VLLLFLVVRE 250 260 270 280 290 300 PPRGAVERHS DLPPLNPTSW WADLRALARN PSFVLSSLGF TAVAFVTGSL ALWAPAFLLR 310 320 330 340 350 360 SRVVLGETPP CLPGDSCSSS DSLIFGLITC LTGVLGVGLG VEISRRLRHS NPRADPLVCA 370 380 390 400 410 420 TGLLGSAPFL FLSLACARGS IVATYIFIFI GETLLSMNWA IVADILLYVV IPTRRSTAEA 430 440 450 460 470 480 FQIVLSHLLG DAGSPYLIGL ISDRLRRNWP PSFLSEFRAL QFSLMLCAFV GALGGAAFLG 490 500 510 520 TAIFIEADRR RAQLHVQGLL HEAGSTDDRI VVPQRGRSTR VPVASVLI
	Isoform 2 [UniParc]. Checksum: 99272BB60BA81889	FASTA	476	51,333
	10 20 30 40 50 60 MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRSAL 70 80 90 100 110 120 IVAVLCYINL LNYMDRFTVA GVLPDIEQFF NIGDSSSGLI QTVFISSYMV LAPVFGYLGD 130 140 150 160 170 180 RYNRKYLMCG GIAFWSLVTL GSSFIPGEHF WLLLLTRGLV GVGEASYSTI APTLIADLFV 190 200 210 220 230 240 ADQRSRMLSI FYFAIPVGSG LGYIAGSKVK DMAGDWHWAL RVTPGLGVVA VLLLFLVVRE 250 260 270 280 290 300 PPRGAVERHS DLPPLNPTSW WADLRALARN LIFGLITCLT GVLGVGLGVE ISRRLRHSNP 310 320 330 340 350 360 RADPLVCATG LLGSAPFLFL SLACARGSIV ATYIFIFIGE TLLSMNWAIV ADILLYVVIP 370 380 390 400 410 420 TRRSTAEAFQ IVLSHLLGDA GSPYLIGLIS DRLRRNWPPS FLSEFRALQF SLMLCAFVGA 430 440 450 460 470 LGGAAFLGTA IFIEADRRRA QLHVQGLLHE AGSTDDRIVV PQRGRSTRVP VASVLI
	Isoform 3 (CRA_d) [UniParc]. Checksum: 4A393F34239B87CF	FASTA	454	49,013
	10 20 30 40 50 60 MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRSAL 70 80 90 100 110 120 IVAVLCYINL LNYMDRFTVA VFISSYMVLA PVFGYLGDRY NRKYLMCGGI AFWSLVTLGS 130 140 150 160 170 180 SFIPGEHFWL LLLTRGLVGV GEASYSTIAP TLIADLFVAD QRSRMLSIFY FAIPVGSGLG 190 200 210 220 230 240 YIAGSKVKDM AGDWHWALRV TPGLGVVAVL LLFLVVREPP RGAVERHSDL PPLNPTSWWA 250 260 270 280 290 300 DLRALARNLI FGLITCLTGV LGVGLGVEIS RRLRHSNPRA DPLVCATGLL GSAPFLFLSL 310 320 330 340 350 360 ACARGSIVAT YIFIFIGETL LSMNWAIVAD ILLYVVIPTR RSTAEAFQIV LSHLLGDAGS 370 380 390 400 410 420 PYLIGLISDR LRRNWPPSFL SEFRALQFSL MLCAFVGALG GAAFLGTAIF IEADRRRAQL 430 440 450 HVQGLLHEAG STDDRIVVPQ RGRSTRVPVA SVLI
	Isoform 4 [UniParc]. Checksum: 63B25A8A61A99C30	FASTA	455	49,139
	10 20 30 40 50 60 MDRFTVAGVL PDIEQFFNIG DSSSGLIQTV FISSYMVLAP VFGYLGDRYN RKYLMCGGIA 70 80 90 100 110 120 FWSLVTLGSS FIPGEHFWLL LLTRGLVGVG EASYSTIAPT LIADLFVADQ RSRMLSIFYF 130 140 150 160 170 180 AIPVGSGLGY IAGSKVKDMA GDWHWALRVT PGLGVVAVLL LFLVVREPPR GAVERHSDLP 190 200 210 220 230 240 PLNPTSWWAD LRALARNPSF VLSSLGFTAV AFVTGSLALW APAFLLRSRV VLGETPPCLP 250 260 270 280 290 300 GDSCSSSDSL IFGLITCLTG VLGVGLGVEI SRRLRHSNPR ADPLVCATGL LGSAPFLFLS 310 320 330 340 350 360 LACARGSIVA TYIFIFIGET LLSMNWAIVA DILLYVVIPT RRSTAEAFQI VLSHLLGDAG 370 380 390 400 410 420 SPYLIGLISD RLRRNWPPSF LSEFRALQFS LMLCAFVGAL GGAAFLGTAI FIEADRRRAQ 430 440 450 LHVQGLLHEA GSTDDRIVVP QRGRSTRVPV ASVLI
	Isoform 5 [UniParc]. Checksum: 07FF7E3B57DF8B8A	FASTA	229	24,594
	10 20 30 40 50 60 MAGSDTAPFL SQADDPDDGP VPGTPGLPGS TGNPKSEEPE VPDQEGLQRI TGLSPGRSAL 70 80 90 100 110 120 IVAVLCYINL LNYMDRFTVA GVLPDIEQFF NIGDSSSGLI QTVFISSYMV LAPVFGYLGD 130 140 150 160 170 180 RYNRKYLMCG GIAFWSLVTL GSSFIPGEHF WLLLLTRGLV GVGEASYSTI APTLIADLFV 190 200 210 220 ADQRSRMLSI FYFAIPVGSG LGYIAGSKVK DMAGDWHWAL RVSLVLAWG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster." Nakano Y., Fujitani K., Kurihara J., Ragan J., Usui-Aoki K., Shimoda L., Lukacsovich T., Suzuki K., Sezaki M., Sano Y., Ueda R., Awano W., Kaneda M., Umeda M., Yamamoto D. Mol. Cell. Biol. 21:3775-3788(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5). Tissue: Brain.
[3]	"Large-scale cDNA transfection screening for genes related to cancer development and progression." Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X. , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J. Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Mammary cancer.
[5]	"The sequence and analysis of duplication-rich human chromosome 16." Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A. Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT PRO-230. Tissue: Blood, Brain, Pancreas and Skin.
[8]	"HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death." Yanagisawa H., Miyashita T., Nakano Y., Yamamoto D. Cell Death Differ. 10:798-807(2003) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH BCL2 AND BCL2L1.
[9]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-518, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF212371 mRNA. Translation: AAG43830.1. AK095677 mRNA. Translation: BAC04603.1. AK289787 mRNA. Translation: BAF82476.1. AF370423 mRNA. Translation: AAQ15259.1. Sequence problems. AL390215 mRNA. Translation: CAB99229.1. AC109460 Genomic DNA. No translation available. CH471267 Genomic DNA. Translation: EAW52018.1. CH471267 Genomic DNA. Translation: EAW52019.1. BC006156 mRNA. Translation: AAH06156.1. BC008325 mRNA. Translation: AAH08325.1. BC038961 mRNA. Translation: AAH38961.1. BC047741 mRNA. Translation: AAH47741.1. BC065235 mRNA. Translation: AAH65235.1.
IPI	IPI00152429. IPI00384364. IPI00640928. IPI00645679. IPI00921141.
RefSeq	NP_001135920.1. NM_001142448.1. NP_001135921.1. NM_001142449.1. NP_001135922.1. NM_001142450.1. NP_001135923.1. NM_001142451.1. NP_114427.1. NM_032038.2.
UniGene	Hs.617449.
3D structure databases
ProteinModelPortal	Q9H2V7.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9H2V7. 7 interactions.
MINT	MINT-2817616.
Protein family/group databases
TCDB	2.A.1.49.2. major facilitator superfamily (MFS).
PTM databases
PhosphoSite	Q9H2V7.
Polymorphism databases
DMDM	74733566.
Proteomic databases
PaxDb	Q9H2V7.
PRIDE	Q9H2V7.
Protocols and materials databases
DNASU	83985.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000311008; ENSP00000309945; ENSG00000169682. ENST00000323081; ENSP00000318228; ENSG00000169682. ENST00000334536; ENSP00000335494; ENSG00000169682. ENST00000352260; ENSP00000306050; ENSG00000169682.
GeneID	83985.
KEGG	hsa:83985.
UCSC	uc002drx.2. human. uc002dry.2. human. uc002drz.2. human. uc010byp.2. human.
Organism-specific databases
CTD	83985.
GeneCards	GC16P028986.
HGNC	HGNC:30621. SPNS1.
HPA	HPA041995. HPA042988.
MIM	612583. gene.
neXtProt	NX_Q9H2V7.
PharmGKB	PA162404561.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0477.
HOVERGEN	HBG055503.
InParanoid	Q9H2V7.
OMA	WQILISH.
OrthoDB	EOG451DQM.
PhylomeDB	Q9H2V7.
Gene expression databases
ArrayExpress	Q9H2V7.
Bgee	Q9H2V7.
CleanEx	HS_SPIN1. HS_SPNS1.
Genevestigator	Q9H2V7.
Family and domain databases
InterPro	IPR011701. MFS. IPR020846. MFS_dom. IPR016196. MFS_dom_general_subst_transpt. [Graphical view]
Pfam	PF07690. MFS_1. 1 hit. [Graphical view]
SUPFAM	SSF103473. MFS_gen_substrate_transporter. 1 hit.
PROSITE	PS50850. MFS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	83985.
NextBio	73114.
SOURCE	Search...

Entry information

Entry name

SPNS1_HUMAN

Accession

Primary (citable) accession number: Q9H2V7
Secondary accession number(s): B5MDM9 , Q6P182, Q71RB5, Q7L541, Q86VU7, Q8N953, Q8TCS5, Q9BRN5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	March 1, 2001
Last modified:	May 29, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.