Q9H2J7 (S6A15_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sodium-dependent neutral amino acid transporter B(0)AT2

Alternative name(s):
Sodium- and chloride-dependent neurotransmitter transporter NTT73
Sodium-coupled branched-chain amino-acid transporter 1
Solute carrier family 6 member 15
Transporter v7-3

Gene names

Name:	SLC6A15
Synonyms:	B0AT2, NTT73, SBAT1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	730 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. Ref.6
Subcellular location	Membrane; Multi-pass membrane protein Probable.
Tissue specificity	Almost exclusively expressed in the brain. Ref.6
Sequence similarities	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily. [View classification]
Biophysicochemical properties	Kinetic parameters: KM=0.16 mM for L-leucine (at pH 7.5, 100 mM NaCL, -70 mV) Ref.6 KM=0.16 mM for L-valine (at pH 7.5, 100 mM NaCL, -70 mV)) KM=0.08 mM for L-isoleucine (at pH 7.5, 100 mM NaCL, -70 mV) KM=0.11 mM for L-methionine (at pH 7.5, 100 mM NaCL, -70 mV) KM=0.38 mM for L-proline (at pH 7.5, 100 mM NaCL, -70 mV) pH dependence: Optimum pH is 7.5-8.5. Strongly inhibited at acidic PH.

Ontologies

Keywords
Biological process	Amino-acid transport Ion transport Neurotransmitter transport Sodium transport Symport Transport
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
Ligand	Sodium
PTM	Glycoprotein Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	leucine transport Inferred from sequence or structural similarity. Source: UniProtKB proline transport Inferred from sequence or structural similarity. Source: UniProtKB transmembrane transport Traceable author statement. Source: Reactome
Cellular_component	integral to membrane Non-traceable author statement Ref.1. Source: UniProtKB integral to plasma membrane Inferred from electronic annotation. Source: InterPro plasma membrane Traceable author statement. Source: Reactome
Molecular_function	neurotransmitter transporter activity Non-traceable author statement Ref.1. Source: UniProtKB neurotransmitter:sodium symporter activity Inferred from electronic annotation. Source: InterPro proline:sodium symporter activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9H2J7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9H2J7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     253-289: IIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPK → VSMLEPFLILLITISGFIPLSNSVTDFCGQITHNTSF
     290-730: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q9H2J7-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-107: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 730	730	Sodium-dependent neutral amino acid transporter B(0)AT2		PRO_0000214798
Regions
	Topological domain	1 – 69	69	Cytoplasmic Potential
	Transmembrane	70 – 90	21	Helical; Name=1; Potential
	Transmembrane	98 – 117	20	Helical; Name=2; Potential
	Transmembrane	142 – 162	21	Helical; Name=3; Potential
	Topological domain	163 – 225	63	Extracellular Potential
	Transmembrane	226 – 244	19	Helical; Name=4; Potential
	Transmembrane	253 – 270	18	Helical; Name=5; Potential
	Transmembrane	306 – 323	18	Helical; Name=6; Potential
	Transmembrane	335 – 356	22	Helical; Name=7; Potential
	Topological domain	357 – 452	96	Extracellular Potential
	Transmembrane	453 – 472	20	Helical; Name=8; Potential
	Transmembrane	496 – 514	19	Helical; Name=9; Potential
	Transmembrane	530 – 550	21	Helical; Name=10; Potential
	Transmembrane	571 – 592	22	Helical; Name=11; Potential
	Transmembrane	620 – 642	23	Helical; Name=12; Potential
	Topological domain	643 – 730	88	Cytoplasmic Potential
Amino acid modifications
	Modified residue	55	1	Phosphoserine Ref.7
	Modified residue	687	1	Phosphoserine Ref.7
	Glycosylation	187	1	N-linked (GlcNAc...) Potential
	Glycosylation	213	1	N-linked (GlcNAc...) Potential
	Glycosylation	383	1	N-linked (GlcNAc...) Potential
	Glycosylation	394	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 107	107	Missing in isoform 3.		VSP_045192
	Alternative sequence	253 – 289	37	IIYFS…MFTPK → VSMLEPFLILLITISGFIPL SNSVTDFCGQITHNTSF in isoform 2.		VSP_043030
	Alternative sequence	290 – 730	441	Missing in isoform 2.		VSP_043031
	Natural variant	400	1	A → V. Ref.2 Corresponds to variant rs12424429 [ dbSNP | Ensembl ].		VAR_052065
	Natural variant	603	1	I → M. Corresponds to variant rs3782369 [ dbSNP | Ensembl ].		VAR_052066

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 45963118E06CFFE6	FASTA	730	81,836
	10 20 30 40 50 60 MPKNSKVVKR ELDDDVTESV KDLLSNEDAA DDAFKTSELI VDGQEEKDTD VEEGSEVEDE 70 80 90 100 110 120 RPAWNSKLQY ILAQVGFSVG LGNVWRFPYL CQKNGGGAYL LPYLILLMVI GIPLFFLELS 130 140 150 160 170 180 VGQRIRRGSI GVWNYISPKL GGIGFASCVV CYFVALYYNV IIGWSLFYFS QSFQQPLPWD 190 200 210 220 230 240 QCPLVKNASH TFVEPECEQS SATTYYWYRE ALNISSSISE SGGLNWKMTI CLLAAWVMVC 250 260 270 280 290 300 LAMIKGIQSS GKIIYFSSLF PYVVLICFLI RAFLLNGSID GIRHMFTPKL EIMLEPKVWR 310 320 330 340 350 360 EAATQVFFAL GLGFGGVIAF SSYNKRDNNC HFDAVLVSFI NFFTSVLATL VVFAVLGFKA 370 380 390 400 410 420 NVINEKCITQ NSETIMKFLK MGNISQDIIP HHINLSTVTA EDYHLVYDII QKVKEEEFPA 430 440 450 460 470 480 LHLNSCKIEE ELNKAVQGTG LAFIAFTEAM THFPASPFWS VMFFLMLVNL GLGSMFGTIE 490 500 510 520 530 540 GIVTPIVDTF KVRKEILTVI CCLLAFCIGL IFVQRSGNYF VTMFDDYSAT LPLLIVVILE 550 560 570 580 590 600 NIAVCFVYGI DKFMEDLKDM LGFAPSRYYY YMWKYISPLM LLSLLIASVV NMGLSPPGYN 610 620 630 640 650 660 AWIEDKASEE FLSYPTWGLV VCVSLVVFAI LPVPVVFIVR RFNLIDDSSG NLASVTYKRG 670 680 690 700 710 720 RVLKEPVNLE GDDTSLIHGK IPSEMPSPNF GKNIYRKQSG SPTLDTAPNG RYGIGYLMAD 730 IMPDMPESDL
	Isoform 2 [UniParc]. Checksum: AB0768CD8F74BF47	FASTA	289	32,264
	10 20 30 40 50 60 MPKNSKVVKR ELDDDVTESV KDLLSNEDAA DDAFKTSELI VDGQEEKDTD VEEGSEVEDE 70 80 90 100 110 120 RPAWNSKLQY ILAQVGFSVG LGNVWRFPYL CQKNGGGAYL LPYLILLMVI GIPLFFLELS 130 140 150 160 170 180 VGQRIRRGSI GVWNYISPKL GGIGFASCVV CYFVALYYNV IIGWSLFYFS QSFQQPLPWD 190 200 210 220 230 240 QCPLVKNASH TFVEPECEQS SATTYYWYRE ALNISSSISE SGGLNWKMTI CLLAAWVMVC 250 260 270 280 LAMIKGIQSS GKVSMLEPFL ILLITISGFI PLSNSVTDFC GQITHNTSF
	Isoform 3 [UniParc]. Checksum: DB10A517144B0643	FASTA	623	69,886
	10 20 30 40 50 60 MVIGIPLFFL ELSVGQRIRR GSIGVWNYIS PKLGGIGFAS CVVCYFVALY YNVIIGWSLF 70 80 90 100 110 120 YFSQSFQQPL PWDQCPLVKN ASHTFVEPEC EQSSATTYYW YREALNISSS ISESGGLNWK 130 140 150 160 170 180 MTICLLAAWV MVCLAMIKGI QSSGKIIYFS SLFPYVVLIC FLIRAFLLNG SIDGIRHMFT 190 200 210 220 230 240 PKLEIMLEPK VWREAATQVF FALGLGFGGV IAFSSYNKRD NNCHFDAVLV SFINFFTSVL 250 260 270 280 290 300 ATLVVFAVLG FKANVINEKC ITQNSETIMK FLKMGNISQD IIPHHINLST VTAEDYHLVY 310 320 330 340 350 360 DIIQKVKEEE FPALHLNSCK IEEELNKAVQ GTGLAFIAFT EAMTHFPASP FWSVMFFLML 370 380 390 400 410 420 VNLGLGSMFG TIEGIVTPIV DTFKVRKEIL TVICCLLAFC IGLIFVQRSG NYFVTMFDDY 430 440 450 460 470 480 SATLPLLIVV ILENIAVCFV YGIDKFMEDL KDMLGFAPSR YYYYMWKYIS PLMLLSLLIA 490 500 510 520 530 540 SVVNMGLSPP GYNAWIEDKA SEEFLSYPTW GLVVCVSLVV FAILPVPVVF IVRRFNLIDD 550 560 570 580 590 600 SSGNLASVTY KRGRVLKEPV NLEGDDTSLI HGKIPSEMPS PNFGKNIYRK QSGSPTLDTA 610 620 PNGRYGIGYL MADIMPDMPE SDL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family." Farmer M.K., Robbins M.J., Medhurst A.D., Campbell D.A., Ellington K., Duckworth M., Brown A.M., Middlemiss D.N., Price G.W., Pangalos M.N. Genomics 70:241-252(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Cerebellum.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3), VARIANT VAL-400. Tissue: Brain.
[3]	"The finished DNA sequence of human chromosome 12." Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A. Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Placenta.
[6]	"Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain." Takanaga H., Mackenzie B., Peng J.B., Hediger M.A. Biochem. Biophys. Res. Commun. 337:892-900(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
[7]	"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M. Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-55 AND SER-687, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF265577 mRNA. Translation: AAG41361.1. AK022853 mRNA. Translation: BAB14274.1. AK291207 mRNA. Translation: BAF83896.1. AK294945 mRNA. Translation: BAH11933.1. AC018922 Genomic DNA. No translation available. AC128657 Genomic DNA. No translation available. CH471054 Genomic DNA. Translation: EAW97389.1. BC070040 mRNA. Translation: AAH70040.1.
IPI	IPI00018071. IPI00165147. IPI00746124.
RefSeq	NP_001139807.1. NM_001146335.2. NP_060527.2. NM_018057.6. NP_877499.1. NM_182767.5.
UniGene	Hs.44424.
3D structure databases
ProteinModelPortal	Q9H2J7.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000266682.
PTM databases
PhosphoSite	Q9H2J7.
Polymorphism databases
DMDM	18202939.
Proteomic databases
PaxDb	Q9H2J7.
PRIDE	Q9H2J7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000266682; ENSP00000266682; ENSG00000072041. ENST00000450363; ENSP00000390706; ENSG00000072041. ENST00000552192; ENSP00000450145; ENSG00000072041.
GeneID	55117.
KEGG	hsa:55117.
UCSC	uc001szv.3. human.
Organism-specific databases
CTD	55117.
GeneCards	GC12M085253.
HGNC	HGNC:13621. SLC6A15.
HPA	HPA008609.
MIM	607971. gene.
neXtProt	NX_Q9H2J7.
PharmGKB	PA37799.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0733.
HOGENOM	HOG000116406.
HOVERGEN	HBG071421.
InParanoid	Q9H2J7.
KO	K05048.
OMA	NSCQIED.
OrthoDB	EOG4N04DJ.
PhylomeDB	Q9H2J7.
Enzyme and pathway databases
Reactome	REACT_15518. Transmembrane transport of small molecules. REACT_19419. Amino acid and oligopeptide SLC transporters. REACT_20679. Amine compound SLC transporters.
Gene expression databases
ArrayExpress	Q9H2J7.
Bgee	Q9H2J7.
CleanEx	HS_SLC6A15.
Genevestigator	Q9H2J7.
GermOnline	ENSG00000072041. Homo sapiens.
Family and domain databases
InterPro	IPR000175. Na/ntran_symport. IPR002438. Na/ntran_symport_orphan. [Graphical view]
PANTHER	PTHR11616. PTHR11616. 1 hit.
Pfam	PF00209. SNF. 1 hit. [Graphical view]
PRINTS	PR00176. NANEUSMPORT. PR01206. ORPHTRNSPORT.
PROSITE	PS00610. NA_NEUROTRAN_SYMP_1. 1 hit. PS00754. NA_NEUROTRAN_SYMP_2. 1 hit. PS50267. NA_NEUROTRAN_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SLC6A15. human.
GenomeRNAi	55117.
NextBio	58754.
SOURCE	Search...

Entry information

Entry name

S6A15_HUMAN

Accession

Primary (citable) accession number: Q9H2J7
Secondary accession number(s): A8K592 , B7Z2P7, E7ESJ5, Q9H9F5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	March 1, 2001
Last modified:	April 3, 2013
This is version 100 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.