Q9H2F9 (CCD68_HUMAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 64.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Coiled-coil domain-containing protein 68 Alternative name(s): Cutaneous T-cell lymphoma-associated antigen se57-1 Short name=CTCL-associated antigen se57-1 | ||
| Gene names |
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| Organism | Homo sapiens (Human) | ||
| Taxonomic identifier | 9606 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 335 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Polymorphism |
| Domain | Coiled coil |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| None. [Check GOA] | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 335 | 335 | Coiled-coil domain-containing protein 68 | PRO_0000264611 | |||||
Regions | |||||||||
| Coiled coil | 101 – 305 | 205 | Potential | ||||||
Natural variations | |||||||||
| Natural variant | 249 | 1 | V → A. Ref.2 Corresponds to variant rs34751112 [ dbSNP | Ensembl ]. | VAR_050762 | |||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Serological detection of cutaneous T-cell lymphoma-associated antigens." Eichmueller S., Usener D., Dummer R., Stein A., Thiel D., Schadendorf D. Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001) [PubMed: 11149944] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY. Tissue: Testis. |
| [2] | "Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-249. Tissue: Trachea. |
| [3] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis. |
| [4] | "Tissue expression and sero-reactivity of tumor-specific antigens in colorectal cancer." Gerhardt A., Usener D., Keese M., Sturm J., Schadendorf D., Eichmueller S. Cancer Lett. 208:197-206(2004) [PubMed: 15142679] [Abstract] Cited for: TISSUE SPECIFICITY. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF273051 mRNA. Translation: AAG34911.1. AK313793 mRNA. Translation: BAG36530.1. BC029508 mRNA. Translation: AAH29508.1. |
| IPI | IPI00018854. |
| RefSeq | NP_001137301.1. NM_001143829.1. NP_079490.1. NM_025214.2. |
| UniGene | Hs.120790. |
3D structure databases | |
| ProteinModelPortal | Q9H2F9. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q9H2F9. 7 interactions. |
| STRING | Q9H2F9. |
PTM databases | |
| PhosphoSite | Q9H2F9. |
Polymorphism databases | |
| DMDM | 74733556. |
Proteomic databases | |
| PRIDE | Q9H2F9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENST00000337363; ENSP00000337209; ENSG00000166510. ENST00000423029; ENSP00000404628; ENSG00000166510. ENST00000432185; ENSP00000413406; ENSG00000166510. |
| GeneID | 80323. |
| KEGG | hsa:80323. |
| UCSC | uc002lfs.1. human. |
Organism-specific databases | |
| CTD | 80323. |
| GeneCards | GC18M052568. |
| H-InvDB | HIX0014461. |
| HGNC | HGNC:24350. CCDC68. |
| neXtProt | NX_Q9H2F9. |
| PharmGKB | PA143485420. |
| GenAtlas | Search... |
Phylogenomic databases | |
| eggNOG | prNOG18923. |
| GeneTree | ENSGT00530000063232. |
| HOGENOM | HBG125739. |
| HOVERGEN | HBG079562. |
| InParanoid | Q9H2F9. |
| OMA | MNKENEV. |
| OrthoDB | EOG4M65HZ. |
| PhylomeDB | Q9H2F9. |
Gene expression databases | |
| ArrayExpress | Q9H2F9. |
| Bgee | Q9H2F9. |
| CleanEx | HS_CCDC68. |
| Genevestigator | Q9H2F9. |
| GermOnline | ENSG00000166510. Homo sapiens. |
Family and domain databases | |
| ProtoNet | Search... |
Other | |
| NextBio | 70843. |
Entry information
| Entry name | CCD68_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q9H2F9 Secondary accession number(s): B2R9I3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Human chromosome 18 Human chromosome 18: entries, gene names and cross-references to MIM |
| Human entries with polymorphisms or disease mutations List of human entries with polymorphisms or disease mutations |
| Human polymorphisms and disease mutations Index of human polymorphisms and disease mutations |

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