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Q9H246

- CA021_HUMAN

UniProt

Q9H246 - CA021_HUMAN

Protein

Uncharacterized protein C1orf21

Gene

C1orf21

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C1orf21
    Alternative name(s):
    Cell proliferation-inducing gene 13 protein
    Gene namesi
    Name:C1orf21
    ORF Names:PIG13
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:15494. C1orf21.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA25610.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 121121Uncharacterized protein C1orf21PRO_0000089246Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei95 – 951Phosphoserine2 Publications
    Modified residuei115 – 1151Phosphoserine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9H246.
    PaxDbiQ9H246.
    PRIDEiQ9H246.

    PTM databases

    PhosphoSiteiQ9H246.

    Expressioni

    Tissue specificityi

    Expressed in spleen, prostate, testis and uterus.1 Publication

    Gene expression databases

    BgeeiQ9H246.
    CleanExiHS_C1orf21.
    GenevestigatoriQ9H246.

    Organism-specific databases

    HPAiHPA026831.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9H246.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG44862.
    HOGENOMiHOG000237337.
    HOVERGENiHBG060374.
    InParanoidiQ9H246.
    OMAiSYQNGDV.
    OrthoDBiEOG7288TB.
    PhylomeDBiQ9H246.
    TreeFamiTF333178.

    Family and domain databases

    InterProiIPR027967. DUF4612.
    [Graphical view]
    PfamiPF15389. DUF4612. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9H246-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGCASAKHVA TVQNEEEAQK GKNYQNGDVF GDEYRIKPVE EVKYMKNGAE    50
    EEQKIAARNQ ENLEKSASSN VRLKTNKEVP GLVHQPRANM HISESQQEFF 100
    RMLDEKIEKG RDYCSEEEDI T 121
    Length:121
    Mass (Da):13,865
    Last modified:March 1, 2001 - v1
    Checksum:i86D7F5C93F70903B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF312864 mRNA. Translation: AAG45338.1.
    AY258286 mRNA. Translation: AAP82231.1.
    AK056487 mRNA. Translation: BAB71196.1.
    AK312062 mRNA. Translation: BAG34998.1.
    AL078645, AL358152 Genomic DNA. Translation: CAI17842.1.
    AL358152, AL078645 Genomic DNA. Translation: CAI22695.1.
    CH471067 Genomic DNA. Translation: EAW91176.1.
    BC028567 mRNA. Translation: AAH28567.1.
    CCDSiCCDS1362.1.
    RefSeqiNP_110433.1. NM_030806.3.
    UniGeneiHs.497159.
    Hs.744936.

    Genome annotation databases

    EnsembliENST00000235307; ENSP00000235307; ENSG00000116667.
    GeneIDi81563.
    KEGGihsa:81563.
    UCSCiuc001gqv.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF312864 mRNA. Translation: AAG45338.1 .
    AY258286 mRNA. Translation: AAP82231.1 .
    AK056487 mRNA. Translation: BAB71196.1 .
    AK312062 mRNA. Translation: BAG34998.1 .
    AL078645 , AL358152 Genomic DNA. Translation: CAI17842.1 .
    AL358152 , AL078645 Genomic DNA. Translation: CAI22695.1 .
    CH471067 Genomic DNA. Translation: EAW91176.1 .
    BC028567 mRNA. Translation: AAH28567.1 .
    CCDSi CCDS1362.1.
    RefSeqi NP_110433.1. NM_030806.3.
    UniGenei Hs.497159.
    Hs.744936.

    3D structure databases

    ProteinModelPortali Q9H246.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9H246.

    Proteomic databases

    MaxQBi Q9H246.
    PaxDbi Q9H246.
    PRIDEi Q9H246.

    Protocols and materials databases

    DNASUi 81563.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000235307 ; ENSP00000235307 ; ENSG00000116667 .
    GeneIDi 81563.
    KEGGi hsa:81563.
    UCSCi uc001gqv.1. human.

    Organism-specific databases

    CTDi 81563.
    GeneCardsi GC01P184356.
    H-InvDB HIX0001416.
    HGNCi HGNC:15494. C1orf21.
    HPAi HPA026831.
    neXtProti NX_Q9H246.
    PharmGKBi PA25610.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG44862.
    HOGENOMi HOG000237337.
    HOVERGENi HBG060374.
    InParanoidi Q9H246.
    OMAi SYQNGDV.
    OrthoDBi EOG7288TB.
    PhylomeDBi Q9H246.
    TreeFami TF333178.

    Miscellaneous databases

    ChiTaRSi C1orf21. human.
    GeneWikii C1orf21.
    C1orf21_(gene).
    GenomeRNAii 81563.
    NextBioi 71842.

    Gene expression databases

    Bgeei Q9H246.
    CleanExi HS_C1orf21.
    Genevestigatori Q9H246.

    Family and domain databases

    InterProi IPR027967. DUF4612.
    [Graphical view ]
    Pfami PF15389. DUF4612. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus."
      Sood R., Bonner T.I., Malakowska I., Stephan D.A., Robbins C.M., Connors T.D., Morgenbesser S.D., Su K., Faruque M.U., Pinkett H., Graham C., Baxevanis A.D., Klinger K.W., Landes G.M., Trent J.M., Carpten J.D.
      Genomics 73:211-222(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    2. "Identification of a human cell proliferation gene 13."
      Kim J.W.
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Trachea.
    4. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Placenta.
    7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.

    Entry informationi

    Entry nameiCA021_HUMAN
    AccessioniPrimary (citable) accession number: Q9H246
    Secondary accession number(s): B2R551
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2005
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM

    External Data

    Dasty 3