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Q9H246

- CA021_HUMAN

UniProt

Q9H246 - CA021_HUMAN

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Protein

Uncharacterized protein C1orf21

Gene

C1orf21

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf21
Alternative name(s):
Cell proliferation-inducing gene 13 protein
Gene namesi
Name:C1orf21
ORF Names:PIG13
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:15494. C1orf21.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25610.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Uncharacterized protein C1orf21PRO_0000089246Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei95 – 951Phosphoserine2 Publications
Modified residuei115 – 1151Phosphoserine2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9H246.
PaxDbiQ9H246.
PRIDEiQ9H246.

PTM databases

PhosphoSiteiQ9H246.

Expressioni

Tissue specificityi

Expressed in spleen, prostate, testis and uterus.1 Publication

Gene expression databases

BgeeiQ9H246.
CleanExiHS_C1orf21.
GenevestigatoriQ9H246.

Organism-specific databases

HPAiHPA026831.

Interactioni

Protein-protein interaction databases

BioGridi123526. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9H246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG44862.
GeneTreeiENSGT00390000014594.
HOGENOMiHOG000237337.
HOVERGENiHBG060374.
InParanoidiQ9H246.
OMAiSYQNGDV.
OrthoDBiEOG7288TB.
PhylomeDBiQ9H246.
TreeFamiTF333178.

Family and domain databases

InterProiIPR027967. DUF4612.
[Graphical view]
PfamiPF15389. DUF4612. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H246-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGCASAKHVA TVQNEEEAQK GKNYQNGDVF GDEYRIKPVE EVKYMKNGAE
60 70 80 90 100
EEQKIAARNQ ENLEKSASSN VRLKTNKEVP GLVHQPRANM HISESQQEFF
110 120
RMLDEKIEKG RDYCSEEEDI T
Length:121
Mass (Da):13,865
Last modified:March 1, 2001 - v1
Checksum:i86D7F5C93F70903B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312864 mRNA. Translation: AAG45338.1.
AY258286 mRNA. Translation: AAP82231.1.
AK056487 mRNA. Translation: BAB71196.1.
AK312062 mRNA. Translation: BAG34998.1.
AL078645, AL358152 Genomic DNA. Translation: CAI17842.1.
AL358152, AL078645 Genomic DNA. Translation: CAI22695.1.
CH471067 Genomic DNA. Translation: EAW91176.1.
BC028567 mRNA. Translation: AAH28567.1.
CCDSiCCDS1362.1.
RefSeqiNP_110433.1. NM_030806.3.
UniGeneiHs.497159.
Hs.744936.

Genome annotation databases

EnsembliENST00000235307; ENSP00000235307; ENSG00000116667.
GeneIDi81563.
KEGGihsa:81563.
UCSCiuc001gqv.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312864 mRNA. Translation: AAG45338.1 .
AY258286 mRNA. Translation: AAP82231.1 .
AK056487 mRNA. Translation: BAB71196.1 .
AK312062 mRNA. Translation: BAG34998.1 .
AL078645 , AL358152 Genomic DNA. Translation: CAI17842.1 .
AL358152 , AL078645 Genomic DNA. Translation: CAI22695.1 .
CH471067 Genomic DNA. Translation: EAW91176.1 .
BC028567 mRNA. Translation: AAH28567.1 .
CCDSi CCDS1362.1.
RefSeqi NP_110433.1. NM_030806.3.
UniGenei Hs.497159.
Hs.744936.

3D structure databases

ProteinModelPortali Q9H246.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123526. 1 interaction.

PTM databases

PhosphoSitei Q9H246.

Proteomic databases

MaxQBi Q9H246.
PaxDbi Q9H246.
PRIDEi Q9H246.

Protocols and materials databases

DNASUi 81563.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000235307 ; ENSP00000235307 ; ENSG00000116667 .
GeneIDi 81563.
KEGGi hsa:81563.
UCSCi uc001gqv.1. human.

Organism-specific databases

CTDi 81563.
GeneCardsi GC01P184356.
H-InvDB HIX0001416.
HGNCi HGNC:15494. C1orf21.
HPAi HPA026831.
neXtProti NX_Q9H246.
PharmGKBi PA25610.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG44862.
GeneTreei ENSGT00390000014594.
HOGENOMi HOG000237337.
HOVERGENi HBG060374.
InParanoidi Q9H246.
OMAi SYQNGDV.
OrthoDBi EOG7288TB.
PhylomeDBi Q9H246.
TreeFami TF333178.

Miscellaneous databases

ChiTaRSi C1orf21. human.
GeneWikii C1orf21.
C1orf21_(gene).
GenomeRNAii 81563.
NextBioi 71842.

Gene expression databases

Bgeei Q9H246.
CleanExi HS_C1orf21.
Genevestigatori Q9H246.

Family and domain databases

InterProi IPR027967. DUF4612.
[Graphical view ]
Pfami PF15389. DUF4612. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus."
    Sood R., Bonner T.I., Malakowska I., Stephan D.A., Robbins C.M., Connors T.D., Morgenbesser S.D., Su K., Faruque M.U., Pinkett H., Graham C., Baxevanis A.D., Klinger K.W., Landes G.M., Trent J.M., Carpten J.D.
    Genomics 73:211-222(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
  2. "Identification of a human cell proliferation gene 13."
    Kim J.W.
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Trachea.
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-95 AND SER-115, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.

Entry informationi

Entry nameiCA021_HUMAN
AccessioniPrimary (citable) accession number: Q9H246
Secondary accession number(s): B2R551
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM

External Data

Dasty 3