Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mesoderm development candidate 1

Gene

MESDC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mesoderm development candidate 1
Gene namesi
Name:MESDC1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:13519. MESDC1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30760.

Polymorphism and mutation databases

BioMutaiMESDC1.
DMDMi24418561.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedCombined sources
Chaini2 – 362361Mesoderm development candidate 1PRO_0000096441Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineCombined sources

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ9H1K6.
PaxDbiQ9H1K6.
PRIDEiQ9H1K6.

PTM databases

iPTMnetiQ9H1K6.
PhosphoSiteiQ9H1K6.

Expressioni

Gene expression databases

BgeeiQ9H1K6.
CleanExiHS_MESDC1.
GenevisibleiQ9H1K6. HS.

Interactioni

Protein-protein interaction databases

BioGridi121865. 1 interaction.
STRINGi9606.ENSP00000267984.

Structurei

3D structure databases

ProteinModelPortaliQ9H1K6.
SMRiQ9H1K6. Positions 74-313.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4261. Eukaryota.
ENOG410XQ0V. LUCA.
GeneTreeiENSGT00550000074542.
HOGENOMiHOG000294219.
HOVERGENiHBG052459.
InParanoidiQ9H1K6.
OMAiCRDTVIA.
OrthoDBiEOG7673B2.
PhylomeDBiQ9H1K6.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9H1K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGSAGKPT GEAASPAPAS AIGGASSQPR KRLVSVCDHC KGKMQLVADL
60 70 80 90 100
LLLSSEARPV LFEGPASSGA GAESFEQCRD TIIARTKGLS ILTHDVQSQL
110 120 130 140 150
NMGRFGEAGD SLVELGDLVV SLTECSAHAA YLAAVATPGA QPAQPGLVDR
160 170 180 190 200
YRVTRCRHEV EQGCAVLRAT PLADMTPQLL LEVSQGLSRN LKFLTDACAL
210 220 230 240 250
ASDKSRDRFS REQFKLGVKC MSTSASALLA CVREVKVAPS ELARSRCALF
260 270 280 290 300
SGPLVQAVSA LVGFATEPQF LGRAAAVSAE GKAVQTAILG GAMSVVSACV
310 320 330 340 350
LLTQCLRDLA QHPDGGAKMS DHRERLRNSA CAVSEGCTLL SQALRERSSP
360
RTLPPVNSNS VN
Length:362
Mass (Da):37,758
Last modified:March 1, 2001 - v1
Checksum:i37BF391D663E1D6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007810 mRNA. Translation: AAG41058.1.
BC084554 mRNA. Translation: AAH84554.1.
CCDSiCCDS10316.1.
RefSeqiNP_072088.1. NM_022566.2.
UniGeneiHs.513071.

Genome annotation databases

EnsembliENST00000267984; ENSP00000267984; ENSG00000140406.
GeneIDi59274.
KEGGihsa:59274.
UCSCiuc002bfz.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007810 mRNA. Translation: AAG41058.1.
BC084554 mRNA. Translation: AAH84554.1.
CCDSiCCDS10316.1.
RefSeqiNP_072088.1. NM_022566.2.
UniGeneiHs.513071.

3D structure databases

ProteinModelPortaliQ9H1K6.
SMRiQ9H1K6. Positions 74-313.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121865. 1 interaction.
STRINGi9606.ENSP00000267984.

PTM databases

iPTMnetiQ9H1K6.
PhosphoSiteiQ9H1K6.

Polymorphism and mutation databases

BioMutaiMESDC1.
DMDMi24418561.

Proteomic databases

MaxQBiQ9H1K6.
PaxDbiQ9H1K6.
PRIDEiQ9H1K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000267984; ENSP00000267984; ENSG00000140406.
GeneIDi59274.
KEGGihsa:59274.
UCSCiuc002bfz.4. human.

Organism-specific databases

CTDi59274.
GeneCardsiMESDC1.
HGNCiHGNC:13519. MESDC1.
MIMi615466. gene.
neXtProtiNX_Q9H1K6.
PharmGKBiPA30760.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4261. Eukaryota.
ENOG410XQ0V. LUCA.
GeneTreeiENSGT00550000074542.
HOGENOMiHOG000294219.
HOVERGENiHBG052459.
InParanoidiQ9H1K6.
OMAiCRDTVIA.
OrthoDBiEOG7673B2.
PhylomeDBiQ9H1K6.

Miscellaneous databases

ChiTaRSiMESDC1. human.
GenomeRNAii59274.
PROiQ9H1K6.
SOURCEiSearch...

Gene expression databases

BgeeiQ9H1K6.
CleanExiHS_MESDC1.
GenevisibleiQ9H1K6. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis."
    Wines M.E., Lee L., Katari M.S., Zhang L., DeRossi C., Shi Y., Perkins S., Feldman M., McCombie W.R., Holdener B.C.
    Genomics 72:88-98(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Retina.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Skin.
  3. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiMESD1_HUMAN
AccessioniPrimary (citable) accession number: Q9H1K6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: March 1, 2001
Last modified: June 8, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.