Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM49A

Gene

FAM49A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM49A
Gene namesi
Name:FAM49A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:25373. FAM49A.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA128394730.

Polymorphism and mutation databases

BioMutaiFAM49A.
DMDMi52782791.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323Protein FAM49APRO_0000187058Add
BLAST

Proteomic databases

EPDiQ9H0Q0.
MaxQBiQ9H0Q0.
PaxDbiQ9H0Q0.
PRIDEiQ9H0Q0.

PTM databases

iPTMnetiQ9H0Q0.
PhosphoSiteiQ9H0Q0.
SwissPalmiQ9H0Q0.

Expressioni

Gene expression databases

BgeeiQ9H0Q0.
CleanExiHS_FAM49A.
ExpressionAtlasiQ9H0Q0. baseline and differential.
GenevisibleiQ9H0Q0. HS.

Organism-specific databases

HPAiCAB017847.

Interactioni

Protein-protein interaction databases

BioGridi123517. 1 interaction.
MINTiMINT-3065986.
STRINGi9606.ENSP00000347744.

Structurei

3D structure databases

ProteinModelPortaliQ9H0Q0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM49 family.Curated

Phylogenomic databases

eggNOGiKOG3951. Eukaryota.
ENOG410XQDW. LUCA.
GeneTreeiENSGT00390000015159.
HOGENOMiHOG000007560.
HOVERGENiHBG057586.
InParanoidiQ9H0Q0.
OMAiVKMRTAQ.
OrthoDBiEOG7FXZZN.
PhylomeDBiQ9H0Q0.
TreeFamiTF314541.

Family and domain databases

InterProiIPR009828. DUF1394.
[Graphical view]
PfamiPF07159. DUF1394. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9H0Q0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNLLKVLTR EIENYPHFFL DFENAQPTEG EREIWNQISA VLQDSESILA
60 70 80 90 100
DLQAYKGAGP EIRDAIQNPN DIQLQEKAWN AVCPLVVRLK RFYEFSIRLE
110 120 130 140 150
KALQSLLESL TCPPYTPTQH LEREQALAKE FAEILHFTLR FDELKMRNPA
160 170 180 190 200
IQNDFSYYRR TISRNRINNM HLDIENEVNN EMANRMSLFY AEATPMLKTL
210 220 230 240 250
SNATMHFVSE NKTLPIENTT DCLSTMTSVC KVMLETPEYR SRFTSEETLM
260 270 280 290 300
FCMRVMVGVI ILYDHVHPVG AFCKTSKIDM KGCIKVLKEQ APDSVEGLLN
310 320
ALRFTTKHLN DESTSKQIRA MLQ
Length:323
Mass (Da):37,313
Last modified:March 1, 2001 - v1
Checksum:i21B0CD613FFD6BD5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti29 – 291E → D in BAG51503 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136704 mRNA. Translation: CAB66639.1.
AK055334 mRNA. Translation: BAG51503.1.
AK315065 mRNA. Translation: BAG37539.1.
CR533504 mRNA. Translation: CAG38535.1.
AC104623 Genomic DNA. Translation: AAY24282.1.
CH471053 Genomic DNA. Translation: EAX00879.1.
BC038971 mRNA. Translation: AAH38971.1.
CCDSiCCDS1688.1.
RefSeqiNP_110424.1. NM_030797.3.
XP_005262687.1. XM_005262630.2.
XP_006712171.1. XM_006712108.2.
UniGeneiHs.467769.

Genome annotation databases

EnsembliENST00000381323; ENSP00000370724; ENSG00000197872.
ENST00000406434; ENSP00000384771; ENSG00000197872.
GeneIDi81553.
KEGGihsa:81553.
UCSCiuc002rck.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136704 mRNA. Translation: CAB66639.1.
AK055334 mRNA. Translation: BAG51503.1.
AK315065 mRNA. Translation: BAG37539.1.
CR533504 mRNA. Translation: CAG38535.1.
AC104623 Genomic DNA. Translation: AAY24282.1.
CH471053 Genomic DNA. Translation: EAX00879.1.
BC038971 mRNA. Translation: AAH38971.1.
CCDSiCCDS1688.1.
RefSeqiNP_110424.1. NM_030797.3.
XP_005262687.1. XM_005262630.2.
XP_006712171.1. XM_006712108.2.
UniGeneiHs.467769.

3D structure databases

ProteinModelPortaliQ9H0Q0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123517. 1 interaction.
MINTiMINT-3065986.
STRINGi9606.ENSP00000347744.

PTM databases

iPTMnetiQ9H0Q0.
PhosphoSiteiQ9H0Q0.
SwissPalmiQ9H0Q0.

Polymorphism and mutation databases

BioMutaiFAM49A.
DMDMi52782791.

Proteomic databases

EPDiQ9H0Q0.
MaxQBiQ9H0Q0.
PaxDbiQ9H0Q0.
PRIDEiQ9H0Q0.

Protocols and materials databases

DNASUi81553.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381323; ENSP00000370724; ENSG00000197872.
ENST00000406434; ENSP00000384771; ENSG00000197872.
GeneIDi81553.
KEGGihsa:81553.
UCSCiuc002rck.3. human.

Organism-specific databases

CTDi81553.
GeneCardsiFAM49A.
HGNCiHGNC:25373. FAM49A.
HPAiCAB017847.
neXtProtiNX_Q9H0Q0.
PharmGKBiPA128394730.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3951. Eukaryota.
ENOG410XQDW. LUCA.
GeneTreeiENSGT00390000015159.
HOGENOMiHOG000007560.
HOVERGENiHBG057586.
InParanoidiQ9H0Q0.
OMAiVKMRTAQ.
OrthoDBiEOG7FXZZN.
PhylomeDBiQ9H0Q0.
TreeFamiTF314541.

Miscellaneous databases

ChiTaRSiFAM49A. human.
GeneWikiiFAM49A.
GenomeRNAii81553.
NextBioi35469134.
PROiQ9H0Q0.

Gene expression databases

BgeeiQ9H0Q0.
CleanExiHS_FAM49A.
ExpressionAtlasiQ9H0Q0. baseline and differential.
GenevisibleiQ9H0Q0. HS.

Family and domain databases

InterProiIPR009828. DUF1394.
[Graphical view]
PfamiPF07159. DUF1394. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Placenta.
  3. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiFA49A_HUMAN
AccessioniPrimary (citable) accession number: Q9H0Q0
Secondary accession number(s): B3KNZ1, Q53QW2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: March 1, 2001
Last modified: March 16, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.