Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9H098

- F107B_HUMAN

UniProt

Q9H098 - F107B_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Protein FAM107B

Gene

FAM107B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. sensory perception of sound Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM107B
Gene namesi
Name:FAM107B
Synonyms:C10orf45
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:23726. FAM107B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134902915.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 131130Protein FAM107BPRO_0000230774Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine1 Publication
Modified residuei50 – 501N6-acetyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ9H098.
PaxDbiQ9H098.
PRIDEiQ9H098.

Expressioni

Gene expression databases

BgeeiQ9H098.
CleanExiHS_FAM107B.
ExpressionAtlasiQ9H098. baseline and differential.
GenevestigatoriQ9H098.

Organism-specific databases

HPAiHPA039661.

Interactioni

Protein-protein interaction databases

BioGridi123705. 4 interactions.
IntActiQ9H098. 2 interactions.
MINTiMINT-4712674.
STRINGi9606.ENSP00000181796.

Structurei

3D structure databases

ProteinModelPortaliQ9H098.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili61 – 11252Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the FAM107 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG75700.
GeneTreeiENSGT00390000011228.
HOGENOMiHOG000048230.
HOVERGENiHBG002824.
InParanoidiQ9H098.
OMAiWKARLTK.
OrthoDBiEOG7P02MP.
PhylomeDBiQ9H098.
TreeFamiTF325943.

Family and domain databases

InterProiIPR009533. DUF1151.
[Graphical view]
PANTHERiPTHR16768. PTHR16768. 1 hit.
PfamiPF06625. DUF1151. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9H098-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAEPDYIEDD NPELIRPQKL INPVKTSRNH QDLHRELLMN QKRGLAPQNK
60 70 80 90 100
PELQKVMEKR KRDQVIKQKE EEAQKKKSDL EIELLKRQQK LEQLELEKQK
110 120 130
LQEEQENAPE FVKVKGNLRR TGQEVAQAQE S
Length:131
Mass (Da):15,558
Last modified:March 1, 2001 - v1
Checksum:i6BEC6C5F02F679D4
GO
Isoform 2 (identifier: Q9H098-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MSTWKARLTK...DSYLITRSIM

Note: No experimental confirmation available.

Show »
Length:306
Mass (Da):34,759
Checksum:i4AD303B43DCE2E40
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MSTWKARLTKRLKSPSRSMH PFPCSALLACFGNTRESASF NQSGVADTHSTVRVQPVAKA GRQPRHPSAEGAPEKRQDSS THAERNGSANRNSSHRTAAQ PAETPEDVPGSLDDGADCEA VVFHASIPRPSIIDTPKEEE FREEPKCLELEQKMTSDSPP EDIDHKDSYLITRSIM in isoform 2. 1 PublicationVSP_037527

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL136885 mRNA. Translation: CAB66819.1.
CR533466 mRNA. Translation: CAG38497.1.
AK127413 mRNA. Translation: BAC86966.1.
AK289959 mRNA. Translation: BAF82648.1.
AL158168 Genomic DNA. No translation available.
AC069544 Genomic DNA. No translation available.
AL157706 Genomic DNA. Translation: CAI12270.1.
AL157706 Genomic DNA. Translation: CAI12271.1.
AL157706 Genomic DNA. Translation: CAI12272.1.
CH471072 Genomic DNA. Translation: EAW86268.1.
CH471072 Genomic DNA. Translation: EAW86269.1.
CH471072 Genomic DNA. Translation: EAW86270.1.
BC004872 mRNA. Translation: AAH04872.1.
BC064407 mRNA. Translation: AAH64407.1.
BC072452 mRNA. Translation: AAH72452.1.
CCDSiCCDS60486.1. [Q9H098-1]
CCDS7102.1. [Q9H098-2]
RefSeqiNP_001269624.1. NM_001282695.1. [Q9H098-1]
NP_001269625.1. NM_001282696.1. [Q9H098-1]
NP_001269626.1. NM_001282697.1. [Q9H098-1]
NP_001269627.1. NM_001282698.1. [Q9H098-1]
NP_001269628.1. NM_001282699.1. [Q9H098-1]
NP_001269629.1. NM_001282700.1. [Q9H098-1]
NP_001269630.1. NM_001282701.1. [Q9H098-1]
NP_001269631.1. NM_001282702.1. [Q9H098-1]
NP_001269632.1. NM_001282703.1. [Q9H098-1]
NP_113641.2. NM_031453.3. [Q9H098-2]
XP_005252673.1. XM_005252616.1. [Q9H098-1]
UniGeneiHs.446315.

Genome annotation databases

EnsembliENST00000181796; ENSP00000181796; ENSG00000065809. [Q9H098-2]
ENST00000378458; ENSP00000367719; ENSG00000065809. [Q9H098-1]
ENST00000378462; ENSP00000367723; ENSG00000065809. [Q9H098-1]
ENST00000378465; ENSP00000367726; ENSG00000065809. [Q9H098-1]
ENST00000378467; ENSP00000367728; ENSG00000065809. [Q9H098-1]
ENST00000378470; ENSP00000367731; ENSG00000065809. [Q9H098-1]
ENST00000468492; ENSP00000420444; ENSG00000065809. [Q9H098-1]
ENST00000468747; ENSP00000418120; ENSG00000065809. [Q9H098-1]
ENST00000478076; ENSP00000417782; ENSG00000065809. [Q9H098-1]
ENST00000479731; ENSP00000419603; ENSG00000065809. [Q9H098-1]
ENST00000496330; ENSP00000418330; ENSG00000065809. [Q9H098-1]
ENST00000621653; ENSP00000483821; ENSG00000065809. [Q9H098-1]
ENST00000622567; ENSP00000479842; ENSG00000065809. [Q9H098-1]
GeneIDi83641.
KEGGihsa:83641.
UCSCiuc001imx.1. human. [Q9H098-1]
uc001ina.1. human. [Q9H098-2]

Polymorphism databases

DMDMi74752552.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL136885 mRNA. Translation: CAB66819.1 .
CR533466 mRNA. Translation: CAG38497.1 .
AK127413 mRNA. Translation: BAC86966.1 .
AK289959 mRNA. Translation: BAF82648.1 .
AL158168 Genomic DNA. No translation available.
AC069544 Genomic DNA. No translation available.
AL157706 Genomic DNA. Translation: CAI12270.1 .
AL157706 Genomic DNA. Translation: CAI12271.1 .
AL157706 Genomic DNA. Translation: CAI12272.1 .
CH471072 Genomic DNA. Translation: EAW86268.1 .
CH471072 Genomic DNA. Translation: EAW86269.1 .
CH471072 Genomic DNA. Translation: EAW86270.1 .
BC004872 mRNA. Translation: AAH04872.1 .
BC064407 mRNA. Translation: AAH64407.1 .
BC072452 mRNA. Translation: AAH72452.1 .
CCDSi CCDS60486.1. [Q9H098-1 ]
CCDS7102.1. [Q9H098-2 ]
RefSeqi NP_001269624.1. NM_001282695.1. [Q9H098-1 ]
NP_001269625.1. NM_001282696.1. [Q9H098-1 ]
NP_001269626.1. NM_001282697.1. [Q9H098-1 ]
NP_001269627.1. NM_001282698.1. [Q9H098-1 ]
NP_001269628.1. NM_001282699.1. [Q9H098-1 ]
NP_001269629.1. NM_001282700.1. [Q9H098-1 ]
NP_001269630.1. NM_001282701.1. [Q9H098-1 ]
NP_001269631.1. NM_001282702.1. [Q9H098-1 ]
NP_001269632.1. NM_001282703.1. [Q9H098-1 ]
NP_113641.2. NM_031453.3. [Q9H098-2 ]
XP_005252673.1. XM_005252616.1. [Q9H098-1 ]
UniGenei Hs.446315.

3D structure databases

ProteinModelPortali Q9H098.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123705. 4 interactions.
IntActi Q9H098. 2 interactions.
MINTi MINT-4712674.
STRINGi 9606.ENSP00000181796.

Polymorphism databases

DMDMi 74752552.

Proteomic databases

MaxQBi Q9H098.
PaxDbi Q9H098.
PRIDEi Q9H098.

Protocols and materials databases

DNASUi 83641.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000181796 ; ENSP00000181796 ; ENSG00000065809 . [Q9H098-2 ]
ENST00000378458 ; ENSP00000367719 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000378462 ; ENSP00000367723 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000378465 ; ENSP00000367726 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000378467 ; ENSP00000367728 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000378470 ; ENSP00000367731 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000468492 ; ENSP00000420444 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000468747 ; ENSP00000418120 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000478076 ; ENSP00000417782 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000479731 ; ENSP00000419603 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000496330 ; ENSP00000418330 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000621653 ; ENSP00000483821 ; ENSG00000065809 . [Q9H098-1 ]
ENST00000622567 ; ENSP00000479842 ; ENSG00000065809 . [Q9H098-1 ]
GeneIDi 83641.
KEGGi hsa:83641.
UCSCi uc001imx.1. human. [Q9H098-1 ]
uc001ina.1. human. [Q9H098-2 ]

Organism-specific databases

CTDi 83641.
GeneCardsi GC10M014471.
H-InvDB HIX0008665.
HGNCi HGNC:23726. FAM107B.
HPAi HPA039661.
neXtProti NX_Q9H098.
PharmGKBi PA134902915.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG75700.
GeneTreei ENSGT00390000011228.
HOGENOMi HOG000048230.
HOVERGENi HBG002824.
InParanoidi Q9H098.
OMAi WKARLTK.
OrthoDBi EOG7P02MP.
PhylomeDBi Q9H098.
TreeFami TF325943.

Miscellaneous databases

ChiTaRSi FAM107B. human.
GenomeRNAii 83641.
NextBioi 72591.
PROi Q9H098.

Gene expression databases

Bgeei Q9H098.
CleanExi HS_FAM107B.
ExpressionAtlasi Q9H098. baseline and differential.
Genevestigatori Q9H098.

Family and domain databases

InterProi IPR009533. DUF1151.
[Graphical view ]
PANTHERi PTHR16768. PTHR16768. 1 hit.
Pfami PF06625. DUF1151. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis.
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Hippocampus and Thalamus.
  4. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Lymph, PNS and Testis.
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF107B_HUMAN
AccessioniPrimary (citable) accession number: Q9H098
Secondary accession number(s): A8K1P4
, D3DRT2, Q5T9K7, Q5T9K8, Q6ZSI4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3