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Q9GZT8

- GTPC1_HUMAN

UniProt

Q9GZT8 - GTPC1_HUMAN

Protein

Putative GTP cyclohydrolase 1 type 2 NIF3L1

Gene

NIF3L1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 124 (01 Oct 2014)
      Sequence version 2 (13 Nov 2007)
      Previous versions | rss
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    Functioni

    Converts GTP to dihydroneopterin triphosphate.By similarity

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi93 – 931Divalent metal cation 2By similarity
    Metal bindingi131 – 1311Divalent metal cation 1By similarity
    Metal bindingi339 – 3391Divalent metal cation 2By similarity
    Metal bindingi343 – 3431Divalent metal cation 1By similarity
    Metal bindingi343 – 3431Divalent metal cation 2By similarity

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW
    2. GTP cyclohydrolase I activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW
    4. protein binding Source: IntAct
    5. transcription factor binding Source: BHF-UCL

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
    2. positive regulation of transcription, DNA-templated Source: BHF-UCL

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    GTP-binding, Metal-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative GTP cyclohydrolase 1 type 2 NIF3L1 (EC:3.5.4.16)
    Alternative name(s):
    Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein
    GTP cyclohydrolase I
    NIF3-like protein 1
    Gene namesi
    Name:NIF3L1
    Synonyms:ALS2CR1
    ORF Names:MDS015, My018
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:13390. NIF3L1.

    Subcellular locationi

    Cytoplasm 2 Publications

    GO - Cellular componenti

    1. cytoplasm Source: BHF-UCL
    2. mitochondrion Source: Ensembl

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA31629.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 377377Putative GTP cyclohydrolase 1 type 2 NIF3L1PRO_0000147353Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei109 – 1091N6-acetyllysine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ9GZT8.
    PaxDbiQ9GZT8.
    PRIDEiQ9GZT8.

    PTM databases

    PhosphoSiteiQ9GZT8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9GZT8.
    BgeeiQ9GZT8.
    CleanExiHS_NIF3L1.
    GenevestigatoriQ9GZT8.

    Organism-specific databases

    HPAiHPA036335.

    Interactioni

    Subunit structurei

    Homodimer. Interacts with COPS2 By similarity. Interacts with THOC7.By similarity1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    BEND7Q8N7W23EBI-740897,EBI-743382
    DHPSP493663EBI-740897,EBI-741925
    RABAC1Q9UI143EBI-740897,EBI-712367
    TRIP13Q156453EBI-740897,EBI-358993

    Protein-protein interaction databases

    BioGridi121922. 78 interactions.
    IntActiQ9GZT8. 39 interactions.
    MINTiMINT-1438019.
    STRINGi9606.ENSP00000386394.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9GZT8.
    SMRiQ9GZT8. Positions 52-377.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase I type 2 family.Curated

    Phylogenomic databases

    eggNOGiCOG0327.
    HOGENOMiHOG000014260.
    HOVERGENiHBG029337.
    InParanoidiQ9GZT8.
    OMAiCPHTAVD.
    PhylomeDBiQ9GZT8.
    TreeFamiTF324125.

    Family and domain databases

    InterProiIPR002678. GTP_cyclohydrolase_I/Nif3.
    IPR017222. GTP_cyclohydrolase_I/NIF3_euk.
    [Graphical view]
    PANTHERiPTHR13799. PTHR13799. 1 hit.
    PfamiPF01784. NIF3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037490. UCP037490_NIF3_euk. 1 hit.
    SUPFAMiSSF102705. SSF102705. 1 hit.
    TIGRFAMsiTIGR00486. YbgI_SA1388. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9GZT8-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MLSSCVRPVP TTVRFVDSLI CNSSRSFMDL KALLSSLNDF ASLSFAESWD    50
    NVGLLVEPSP PHTVNTLFLT NDLTEEVMEE VLQKKADLIL SYHPPIFRPM 100
    KRITWNTWKE RLVIRALENR VGIYSPHTAY DAAPQGVNNW LAKGLGACTS 150
    RPIHPSKAPN YPTEGNHRVE FNVNYTQDLD KVMSAVKGID GVSVTSFSAR 200
    TGNEEQTRIN LNCTQKALMQ VVDFLSRNKQ LYQKTEILSL EKPLLLHTGM 250
    GRLCTLDESV SLATMIDRIK RHLKLSHIRL ALGVGRTLES QVKVVALCAG 300
    SGSSVLQGVE ADLYLTGEMS HHDTLDAASQ GINVILCEHS NTERGFLSDL 350
    RDMLDSHLEN KINIILSETD RDPLQVV 377
    Length:377
    Mass (Da):41,968
    Last modified:November 13, 2007 - v2
    Checksum:i41BDCADDD81CA0D8
    GO
    Isoform 2 (identifier: Q9GZT8-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-27: Missing.

    Show »
    Length:350
    Mass (Da):38,984
    Checksum:i81F1A5AD35B25ED7
    GO
    Isoform 3 (identifier: Q9GZT8-3) [UniParc]FASTAAdd to Basket

    Also known as: beta

    The sequence of this isoform differs from the canonical sequence as follows:
         243-377: PLLLHTGMGR...ETDRDPLQVV → SLKSKSWPCV...MILWMLLPKE

    Show »
    Length:285
    Mass (Da):32,164
    Checksum:i5084AD8C6E9700EC
    GO

    Sequence cautioni

    The sequence AAG14952.1 differs from that shown. Reason: Frameshift at positions 104 and 109.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti109 – 1091K → E in AAG14952. 1 PublicationCurated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti324 – 3241T → I.
    Corresponds to variant rs7917 [ dbSNP | Ensembl ].
    VAR_037084

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 2727Missing in isoform 2. 4 PublicationsVSP_029328Add
    BLAST
    Alternative sequencei243 – 377135PLLLH…PLQVV → SLKSKSWPCVLVLGAAFCRV LRLTFTSQVRCPIMILWMLL PKE in isoform 3. 1 PublicationVSP_043248Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF283538 mRNA. Translation: AAG44846.1.
    AB038949 mRNA. Translation: BAB32499.1.
    AY251943 mRNA. Translation: AAP84063.1.
    AF060513 mRNA. Translation: AAG43131.1.
    AF182416 mRNA. Translation: AAG14952.1. Frameshift.
    AK023378 mRNA. Translation: BAB14551.1.
    AC005037 Genomic DNA. Translation: AAY14724.1.
    CH471063 Genomic DNA. Translation: EAW70224.1.
    BC007654 mRNA. Translation: AAH07654.1.
    CCDSiCCDS42797.1. [Q9GZT8-2]
    CCDS46485.1. [Q9GZT8-1]
    CCDS46486.1. [Q9GZT8-3]
    RefSeqiNP_001129511.1. NM_001136039.2. [Q9GZT8-1]
    NP_001135827.1. NM_001142355.1. [Q9GZT8-2]
    NP_001135828.1. NM_001142356.1. [Q9GZT8-3]
    NP_068596.2. NM_021824.3. [Q9GZT8-2]
    XP_005246799.1. XM_005246742.2. [Q9GZT8-1]
    XP_006712739.1. XM_006712676.1. [Q9GZT8-3]
    UniGeneiHs.145284.

    Genome annotation databases

    EnsembliENST00000359683; ENSP00000352711; ENSG00000196290. [Q9GZT8-2]
    ENST00000409020; ENSP00000386394; ENSG00000196290. [Q9GZT8-1]
    ENST00000409357; ENSP00000387315; ENSG00000196290. [Q9GZT8-1]
    ENST00000409588; ENSP00000387021; ENSG00000196290. [Q9GZT8-3]
    ENST00000416651; ENSP00000400787; ENSG00000196290. [Q9GZT8-1]
    GeneIDi60491.
    KEGGihsa:60491.
    UCSCiuc002uwl.2. human. [Q9GZT8-1]
    uc002uwq.2. human. [Q9GZT8-3]

    Polymorphism databases

    DMDMi160112850.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF283538 mRNA. Translation: AAG44846.1 .
    AB038949 mRNA. Translation: BAB32499.1 .
    AY251943 mRNA. Translation: AAP84063.1 .
    AF060513 mRNA. Translation: AAG43131.1 .
    AF182416 mRNA. Translation: AAG14952.1 . Frameshift.
    AK023378 mRNA. Translation: BAB14551.1 .
    AC005037 Genomic DNA. Translation: AAY14724.1 .
    CH471063 Genomic DNA. Translation: EAW70224.1 .
    BC007654 mRNA. Translation: AAH07654.1 .
    CCDSi CCDS42797.1. [Q9GZT8-2 ]
    CCDS46485.1. [Q9GZT8-1 ]
    CCDS46486.1. [Q9GZT8-3 ]
    RefSeqi NP_001129511.1. NM_001136039.2. [Q9GZT8-1 ]
    NP_001135827.1. NM_001142355.1. [Q9GZT8-2 ]
    NP_001135828.1. NM_001142356.1. [Q9GZT8-3 ]
    NP_068596.2. NM_021824.3. [Q9GZT8-2 ]
    XP_005246799.1. XM_005246742.2. [Q9GZT8-1 ]
    XP_006712739.1. XM_006712676.1. [Q9GZT8-3 ]
    UniGenei Hs.145284.

    3D structure databases

    ProteinModelPortali Q9GZT8.
    SMRi Q9GZT8. Positions 52-377.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121922. 78 interactions.
    IntActi Q9GZT8. 39 interactions.
    MINTi MINT-1438019.
    STRINGi 9606.ENSP00000386394.

    PTM databases

    PhosphoSitei Q9GZT8.

    Polymorphism databases

    DMDMi 160112850.

    Proteomic databases

    MaxQBi Q9GZT8.
    PaxDbi Q9GZT8.
    PRIDEi Q9GZT8.

    Protocols and materials databases

    DNASUi 60491.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000359683 ; ENSP00000352711 ; ENSG00000196290 . [Q9GZT8-2 ]
    ENST00000409020 ; ENSP00000386394 ; ENSG00000196290 . [Q9GZT8-1 ]
    ENST00000409357 ; ENSP00000387315 ; ENSG00000196290 . [Q9GZT8-1 ]
    ENST00000409588 ; ENSP00000387021 ; ENSG00000196290 . [Q9GZT8-3 ]
    ENST00000416651 ; ENSP00000400787 ; ENSG00000196290 . [Q9GZT8-1 ]
    GeneIDi 60491.
    KEGGi hsa:60491.
    UCSCi uc002uwl.2. human. [Q9GZT8-1 ]
    uc002uwq.2. human. [Q9GZT8-3 ]

    Organism-specific databases

    CTDi 60491.
    GeneCardsi GC02P201718.
    HGNCi HGNC:13390. NIF3L1.
    HPAi HPA036335.
    MIMi 605778. gene.
    neXtProti NX_Q9GZT8.
    PharmGKBi PA31629.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0327.
    HOGENOMi HOG000014260.
    HOVERGENi HBG029337.
    InParanoidi Q9GZT8.
    OMAi CPHTAVD.
    PhylomeDBi Q9GZT8.
    TreeFami TF324125.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .

    Miscellaneous databases

    GeneWikii NIF3L1.
    GenomeRNAii 60491.
    NextBioi 65383.
    PROi Q9GZT8.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9GZT8.
    Bgeei Q9GZT8.
    CleanExi HS_NIF3L1.
    Genevestigatori Q9GZT8.

    Family and domain databases

    InterProi IPR002678. GTP_cyclohydrolase_I/Nif3.
    IPR017222. GTP_cyclohydrolase_I/NIF3_euk.
    [Graphical view ]
    PANTHERi PTHR13799. PTHR13799. 1 hit.
    Pfami PF01784. NIF3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037490. UCP037490_NIF3_euk. 1 hit.
    SUPFAMi SSF102705. SSF102705. 1 hit.
    TIGRFAMsi TIGR00486. YbgI_SA1388. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals."
      Tascou S., Uedelhoven J., Dixkens C., Nayernia K., Engel W., Burfeind P.
      Cytogenet. Cell Genet. 90:330-336(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
    2. "Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2."
      Hadano S., Yanagisawa Y., Skaug J., Fichter K., Nasir J., Martindale D., Koop B.F., Scherer S.W., Nicholson D.W., Rouleau G.A., Ikeda J.-E., Hayden M.R.
      Genomics 71:200-213(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    3. "NIF3L1 interacts with WBSCR14."
      Merla G., Reymond A.
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    4. Mao Y.M., Xie Y., Huang X.Y., Ying K., Dai J.L.
      Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Fetal brain.
    5. "Novel genes expressed in hematopoietic stem/progenitor cells from myelodysplastic syndrome patients."
      Huang C., Qian B., Tu Y., Gu W., Wang Y., Han Z., Chen Z.
      Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Hematopoietic stem cell.
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Ovarian carcinoma.
    7. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Skin.
    10. "Identification and characterization of NIF3L1 BP1, a novel cytoplasmic interaction partner of the NIF3L1 protein."
      Tascou S., Kang T.W., Trappe R., Engel W., Burfeind P.
      Biochem. Biophys. Res. Commun. 309:440-448(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: ALTERNATIVE SPLICING (ISOFORMS 1 AND 2), INTERACTION WITH THOC7, SUBCELLULAR LOCATION.
    11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
      Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-109, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiGTPC1_HUMAN
    AccessioniPrimary (citable) accession number: Q9GZT8
    Secondary accession number(s): Q53TX4
    , Q6X735, Q9H2D2, Q9HC18
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2002
    Last sequence update: November 13, 2007
    Last modified: October 1, 2014
    This is version 124 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3