Q9GZM7 (TINAL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tubulointerstitial nephritis antigen-like

Alternative name(s):
Glucocorticoid-inducible protein 5
Oxidized LDL-responsive gene 2 protein
Short name=OLRG-2
Tubulointerstitial nephritis antigen-related protein
Short name=TIN Ag-related protein
Short name=TIN-Ag-RP

Gene names

Name:	TINAGL1
Synonyms:	GIS5, LCN7, OLRG2, TINAGL
ORF Names:	PP6614, PSEC0088, UNQ204/PRO230

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	467 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein By similarity.
Subcellular location	Secreted Ref.1 Ref.2.
Tissue specificity	Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle cells, but also in cardiac and skeletal muscle cells as well as kidney. Ref.2
Post-translational modification	Glycosylated. Ref.2
Sequence similarities	Belongs to the peptidase C1 family. Contains 1 SMB (somatomedin-B) domain.
Sequence caution	The sequence AAH09048.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB55403.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Secreted
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Signal
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	endosomal transport Traceable author statement Ref.1. Source: UniProtKB immune response Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: InterPro receptor-mediated endocytosis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Ensembl extracellular space Inferred from sequence or structural similarity PubMed 22261194. Source: BHF-UCL
Molecular_function	cysteine-type peptidase activity Inferred from electronic annotation. Source: InterPro extracellular matrix structural constituent Non-traceable author statement Ref.2. Source: UniProtKB polysaccharide binding Inferred from electronic annotation. Source: InterPro scavenger receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9GZM7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9GZM7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-134: Missing.
     135-194: CDQEPCLVDP...SSVMNMHEIY → MVLGSSTQVK...EADRATFILQ
     286-286: G → GYAATGDVGREEGKELRGHGLGHDALSLSAFAPSCCLCR
     365-381: ALMEVHEDFFLYKGGIY → GKPPYPAPWFQKLVPA
     382-467: Missing.

Isoform 3 (identifier: Q9GZM7-3)

The sequence of this isoform differs from the canonical sequence as follows:
     126-156: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Ref.2 Ref.13
	Chain	22 – 467	446	Tubulointerstitial nephritis antigen-like		PRO_0000026482
Regions
	Domain	50 – 98	49	SMB
Amino acid modifications
	Glycosylation	78	1	N-linked (GlcNAc...) Ref.14
	Glycosylation	161	1	N-linked (GlcNAc...) Ref.14
	Disulfide bond	54 ↔ 73		Alternate By similarity
	Disulfide bond	71 ↔ 85		Alternate By similarity
	Disulfide bond	71 ↔ 73		By similarity
	Disulfide bond	77 ↔ 84		By similarity
	Disulfide bond	85 ↔ 92		By similarity
Natural variations
	Alternative sequence	1 – 134	134	Missing in isoform 2.		VSP_013094
	Alternative sequence	126 – 156	31	Missing in isoform 3.		VSP_043712
	Alternative sequence	135 – 194	60	CDQEP…MHEIY → MVLGSSTQVKIGGSWNPAAA GGLKIKLQKALDLVALQCQW APEGQARAEQEADRATFILQ in isoform 2.		VSP_013095
	Alternative sequence	286	1	G → GYAATGDVGREEGKELRGHG LGHDALSLSAFAPSCCLCR in isoform 2.		VSP_013096
	Alternative sequence	365 – 381	17	ALMEV…KGGIY → GKPPYPAPWFQKLVPA in isoform 2.		VSP_013097
	Alternative sequence	382 – 467	86	Missing in isoform 2.		VSP_013098
	Natural variant	69	1	A → S. Corresponds to variant rs17497479 [ dbSNP | Ensembl ].		VAR_051514
Experimental info
	Sequence conflict	333	1	N → Y in AAL55753. Ref.7
	Sequence conflict	377	1	K → E in BAB55403. Ref.8

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: E9D72220E3E7B7D5	FASTA	467	52,387
	10 20 30 40 50 60 MWRCPLGLLL LLPLAGHLAL GAQQGRGRRE LAPGLHLRGI RDAGGRYCQE QDLCCRGRAD 70 80 90 100 110 120 DCALPYLGAI CYCDLFCNRT VSDCCPDFWD FCLGVPPPFP PIQGCMHGGR IYPVLGTYWD 130 140 150 160 170 180 NCNRCTCQEN RQWQCDQEPC LVDPDMIKAI NQGNYGWQAG NHSAFWGMTL DEGIRYRLGT 190 200 210 220 230 240 IRPSSSVMNM HEIYTVLNPG EVLPTAFEAS EKWPNLIHEP LDQGNCAGSW AFSTAAVASD 250 260 270 280 290 300 RVSIHSLGHM TPVLSPQNLL SCDTHQQQGC RGGRLDGAWW FLRRRGVVSD HCYPFSGRER 310 320 330 340 350 360 DEAGPAPPCM MHSRAMGRGK RQATAHCPNS YVNNNDIYQV TPVYRLGSND KEIMKELMEN 370 380 390 400 410 420 GPVQALMEVH EDFFLYKGGI YSHTPVSLGR PERYRRHGTH SVKITGWGEE TLPDGRTLKY 430 440 450 460 WTAANSWGPA WGERGHFRIV RGVNECDIES FVLGVWGRVG MEDMGHH
	Isoform 2 [UniParc]. Checksum: E389D4425C84FB08	FASTA	284	30,845
	10 20 30 40 50 60 MVLGSSTQVK IGGSWNPAAA GGLKIKLQKA LDLVALQCQW APEGQARAEQ EADRATFILQ 70 80 90 100 110 120 TVLNPGEVLP TAFEASEKWP NLIHEPLDQG NCAGSWAFST AAVASDRVSI HSLGHMTPVL 130 140 150 160 170 180 SPQNLLSCDT HQQQGCRGGR LDGAWWFLRR RGYAATGDVG REEGKELRGH GLGHDALSLS 190 200 210 220 230 240 AFAPSCCLCR VVSDHCYPFS GRERDEAGPA PPCMMHSRAM GRGKRQATAH CPNSYVNNND 250 260 270 280 IYQVTPVYRL GSNDKEIMKE LMENGPVQGK PPYPAPWFQK LVPA
	Isoform 3 [UniParc]. Checksum: E66031AF51808DCD	FASTA	436	48,807
	10 20 30 40 50 60 MWRCPLGLLL LLPLAGHLAL GAQQGRGRRE LAPGLHLRGI RDAGGRYCQE QDLCCRGRAD 70 80 90 100 110 120 DCALPYLGAI CYCDLFCNRT VSDCCPDFWD FCLGVPPPFP PIQGCMHGGR IYPVLGTYWD 130 140 150 160 170 180 NCNRCWQAGN HSAFWGMTLD EGIRYRLGTI RPSSSVMNMH EIYTVLNPGE VLPTAFEASE 190 200 210 220 230 240 KWPNLIHEPL DQGNCAGSWA FSTAAVASDR VSIHSLGHMT PVLSPQNLLS CDTHQQQGCR 250 260 270 280 290 300 GGRLDGAWWF LRRRGVVSDH CYPFSGRERD EAGPAPPCMM HSRAMGRGKR QATAHCPNSY 310 320 330 340 350 360 VNNNDIYQVT PVYRLGSNDK EIMKELMENG PVQALMEVHE DFFLYKGGIY SHTPVSLGRP 370 380 390 400 410 420 ERYRRHGTHS VKITGWGEET LPDGRTLKYW TAANSWGPAW GERGHFRIVR GVNECDIESF 430 VLGVWGRVGM EDMGHH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein." Broemme N.C., Wex T., Wex H., Levy B., Lipyansky A., Broemme D. Biochem. Biophys. Res. Commun. 271:474-480(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1), SUBCELLULAR LOCATION. Tissue: Muscle.
[2]	"TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells." Wex T., Lipyansky A., Broemme N.C., Wex H., Guan X.Q., Broemme D. Biochemistry 40:1350-1357(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 22-27, TISSUE SPECIFICITY, GLYCOSYLATION, SUBCELLULAR LOCATION. Tissue: Muscle.
[3]	"Identification of oxidized-LDL responsive gene 2 (OLRG-2), encoding a novel extracellular matrix protein in vascular endothelial cells." Zhang K.M., Chen B.S. Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[4]	"Identification of a novel glucocorticoid-inducible cDNA partially homologous to tubulointerstitial nephritis antigen." Yoshida H., Takaishi K., Harada M., Nagasaka T., Tsurufuji S., Taniguchi M. Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1).
[5]	"The nucleotide sequence of a long cDNA clone isolated from human spleen." Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Placenta.
[6]	"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M. Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[7]	"Large-scale cDNA transfection screening for genes related to cancer development and progression." Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X. , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J. Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
[8]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3). Tissue: Kidney, Placenta and Trachea.
[9]	"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y. , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T. DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Placenta.
[10]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[11]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[12]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Colon and Pancreas.
[13]	"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Zhang Z., Henzel W.J. Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 22-36.
[14]	"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H. J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-78 AND ASN-161, MASS SPECTROMETRY. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF236155 , AF236151, AF236152, AF236153, AF236154 Genomic DNA. Translation: AAG40154.1. AF236150 mRNA. Translation: AAG38876.1. AF205436 mRNA. Translation: AAG33699.1. AB050716 mRNA. Translation: BAB18636.1. AB050719 Genomic DNA. Translation: BAB18727.1. AK074124 mRNA. Translation: BAB84950.1. AY358421 mRNA. Translation: AAQ88787.1. AF289569 mRNA. Translation: AAL55753.1. AK027839 mRNA. Translation: BAB55403.1. Different initiation. AK292770 mRNA. Translation: BAF85459.1. AK298382 mRNA. Translation: BAG60618.1. AK075398 mRNA. Translation: BAC11596.1. AC114488 Genomic DNA. No translation available. CH471059 Genomic DNA. Translation: EAX07604.1. CH471059 Genomic DNA. Translation: EAX07605.1. CH471059 Genomic DNA. Translation: EAX07606.1. BC009048 mRNA. Translation: AAH09048.1. Different initiation. BC064633 mRNA. Translation: AAH64633.1.
RefSeq	NP_001191343.1. NM_001204414.1. NP_001191344.1. NM_001204415.1. NP_071447.1. NM_022164.2.
UniGene	Hs.199368.
3D structure databases
ProteinModelPortal	Q9GZM7.
SMR	Q9GZM7. Positions 145-458.
ModBase	Search...
MobiDB	Search...
Protein-protein interaction databases
BioGrid	122078. 9 interactions.
IntAct	Q9GZM7. 52 interactions.
MINT	MINT-253718.
STRING	9606.ENSP00000271064.
Protein family/group databases
MEROPS	C01.975.
PTM databases
PhosphoSite	Q9GZM7.
Polymorphism databases
DMDM	61213628.
Proteomic databases
PaxDb	Q9GZM7.
PRIDE	Q9GZM7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000271064; ENSP00000271064; ENSG00000142910. ENST00000457433; ENSP00000395137; ENSG00000142910.
GeneID	64129.
KEGG	hsa:64129.
UCSC	uc001bta.3. human.
Organism-specific databases
CTD	64129.
GeneCards	GC01P032042.
HGNC	HGNC:19168. TINAGL1.
HPA	HPA048695.
neXtProt	NX_Q9GZM7.
PharmGKB	PA38810.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG310046.
HOGENOM	HOG000241342.
HOVERGEN	HBG053961.
InParanoid	Q9GZM7.
OMA	DNCNRCT.
OrthoDB	EOG7SV0V1.
PhylomeDB	Q9GZM7.
TreeFam	TF313765.
Gene expression databases
ArrayExpress	Q9GZM7.
Bgee	Q9GZM7.
CleanEx	HS_TINAGL1.
Genevestigator	Q9GZM7.
Family and domain databases
InterPro	IPR025660. Pept_his_AS. IPR013128. Peptidase_C1A. IPR000668. Peptidase_C1A_C. IPR001212. Somatomedin_B_dom. [Graphical view]
PANTHER	PTHR12411. PTHR12411. 1 hit.
Pfam	PF00112. Peptidase_C1. 1 hit. [Graphical view]
SMART	SM00645. Pept_C1. 1 hit. SM00201. SO. 1 hit. [Graphical view]
PROSITE	PS00524. SMB_1. 1 hit. PS50958. SMB_2. 1 hit. PS00639. THIOL_PROTEASE_HIS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	TINAGL1. human.
GeneWiki	TINAGL1.
GenomeRNAi	64129.
NextBio	66016.
PRO	Q9GZM7.

Entry information

Entry name

TINAL_HUMAN

Accession

Primary (citable) accession number: Q9GZM7
Secondary accession number(s): A8K9Q5 , B4DPK6, D3DPN8, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	March 1, 2001
Last modified:	February 19, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.