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Protein
Submitted name:

Proteasome Regulatory Particle, Non-ATPase-like

Gene

rpn-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • nematode larval development Source: WormBase
  • proteasome-mediated ubiquitin-dependent protein catabolic process Source: GO_Central
  • regulation of protein catabolic process Source: InterPro
  • reproduction Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-174113. SCF-beta-TrCP mediated degradation of Emi1.
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4641258. Degradation of DVL.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8854050. FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-8948751. Regulation of PTEN stability and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, Non-ATPase-likeImported
Gene namesi
Name:rpn-1Imported
ORF Names:CELE_T22D1.9Imported, T22D1.9Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT22D1.9; CE17253; WBGene00004458; rpn-1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiQ9GZH5.
PaxDbiQ9GZH5.
PeptideAtlasiQ9GZH5.

Expressioni

Gene expression databases

BgeeiWBGene00004458.

Interactioni

Protein-protein interaction databases

IntActiQ9GZH5. 7 interactors.
MINTiMINT-210711.
STRINGi6239.T22D1.9.1.

Structurei

3D structure databases

ProteinModelPortaliQ9GZH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2005. Eukaryota.
COG5110. LUCA.
GeneTreeiENSGT00550000074983.
HOGENOMiHOG000176022.
InParanoidiQ9GZH5.
KOiK03028.
OMAiMVDICAY.
OrthoDBiEOG091G04TC.
PhylomeDBiQ9GZH5.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR016643. 26S_Psome_Rpn1.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR002015. Proteasome/cyclosome_rpt.
PANTHERiPTHR10943:SF1. PTHR10943:SF1. 1 hit.
PfamiView protein in Pfam
PF01851. PC_rep. 1 hit.
PIRSFiPIRSF015965. 26S_Psome_Rpn1. 1 hit.
SUPFAMiSSF48371. SSF48371. 6 hits.

Sequencei

Sequence statusi: Complete.

Q9GZH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVATTQQTPK EADKKKADDK KVPEKAEPKK EEMSEEDQKL EEDLNLLVQR
60 70 80 90 100
LSEPDTTLYK PSLETMRTLI RASTTSMTSV PKPLKFMRPH YNKMKEIFTS
110 120 130 140 150
IVAPDVKKLC ADIISVLAMT SDERTDTINY RILGSHEPIG DWGHEYVRHL
160 170 180 190 200
AMEMSEEWKK EGTSDARKAE LLKLTQDIVS HHMKHNAEVE ACDLLIEIER
210 220 230 240 250
IDLLISYVQE VDHQRVCLYL LSCAPLTPDP DNIILIRTAL QLYLKFNRYL
260 270 280 290 300
EAVRCAIMVN DIPQVHQIFA KASDPLLRKQ MAILLGRHQI FLDYEGSADS
310 320 330 340 350
DALAELNSNA HLYEYFHSLA RELDIMEPKT PEGIYKSHLE HSRPFGNSAQ
360 370 380 390 400
PDSTRMNLAA ALVNGFVNCG FGVDKMMAET EEASRWFYKN KEYGMLTAAA
410 420 430 440 450
SQGLIWRWDI DTGLAQCDRF LYINDDYIKA GTLLAIGIIS SGIQDACDPA
460 470 480 490 500
SALLLDHVQS DRSIMRVGSI LGLGLAYANS KRETVTKNEE RGVIFELKKV
510 520 530 540 550
LSDQKPSAIP EVKGLAGLSL GLILVGTADA EAAMEMLQAL MDKSETELTD
560 570 580 590 600
PNMRFLALGI ALIFLQTQDK SDVFVESLRS LPDPFGAMVS TLVEVCAYAG
610 620 630 640 650
TGNVLKIQKL LHLCSEHYET PAAEKKTAAS RGPRGPAPAA ATPARPAAQP
660 670 680 690 700
GNVNVAGTPA PTGTPAVAPA APRRDLPGAA SAATPGAPET AAADATPAPP
710 720 730 740 750
AKPDLSSQQA VAVLGIGLIA MGDDIGSQMA LRMFGHLIRY GEPVIRRAVP
760 770 780 790 800
LALSLLSVSN PQLNILETLS KFSHDSDADT AHNAIFAMGL VGAGTNNARL
810 820 830 840 850
VAMLRNLASY HYKDQVSLML VRIAQGLTHL GKGTMTLNPW HSDRQLLSPS
860 870 880 890 900
ALASLLSICF SFLDANNTIL NNRQHYLLYT LVLAMQPRML TTLVEDEMKP
910 920 930 940 950
GSLKQLNVSV RVGQAVDVVA QAGKPKTITG FQTHTTPVLL AHGERAELAN
960 970 980
DEYLSVTPHL EGLVILKKNP DYQPVVVSTK K
Length:981
Mass (Da):107,381
Last modified:March 1, 2001 - v1
Checksum:i802D6D30E7EB3546
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD62025.1.
PIRiT32707.
RefSeqiNP_501064.1. NM_068663.4.
UniGeneiCel.5136.

Genome annotation databases

EnsemblMetazoaiT22D1.9.1; T22D1.9.1; WBGene00004458.
T22D1.9.2; T22D1.9.2; WBGene00004458.
GeneIDi177455.
KEGGicel:CELE_T22D1.9.
UCSCiT22D1.9.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ9GZH5_CAEEL
AccessioniPrimary (citable) accession number: Q9GZH5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 22, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported