Q9GZ71 (TPM_HALDV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Tropomyosin
Organism	Haliotis diversicolor (Abalone) (Sulculus diversicolor)
Taxonomic identifier	36095 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Mollusca › Gastropoda › Vetigastropoda › Haliotoidea › Haliotidae › Haliotis

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
Subunit structure	Homodimer By similarity.
Domain	The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
Sequence similarities	Belongs to the tropomyosin family.

Ontologies

Keywords
Domain	Coiled coil Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	Tropomyosin		PRO_0000205665
Regions
	Coiled coil	1 – 284	284	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9GZ71 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 3AAF5B3F0D3287F7	FASTA	284	32,823
	10 20 30 40 50 60 MDAIKKKMLA MKMEKENAVD RAEQNEQKLR DTEEQKAKIE EDLNNLQKKC ANLENDFDNV 70 80 90 100 110 120 NEQLQEAMAK LETSEKRVTE MEQEVSGTTR KITLLEEDLE RNEERLQTAT ERLEEASKAA 130 140 150 160 170 180 DESERGARVL ESRSLADDER IDQLEAQLKE AKYIAEDAER KYDEAARKLA ITEVDLERAE 190 200 210 220 230 240 ARLEAAEAKI LELEEELKVV GNNMKSLEIS EQEASQREDS YEETIRDLTQ RLKDAENRAT 250 260 270 280 EAERTVSKLQ KEVDRLEDEL LAEKEKYKAI SDELDQTFAE LAGY

References

[1]	"Tropomyosin is the major mollusc allergen: RT-PCR, expression and IgE reactivity." Chu K.H., Wong S.H., Leung P.S.C. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF216518 mRNA. Translation: AAG08987.1.
3D structure databases
ProteinModelPortal	Q9GZ71.
SMR	Q9GZ71. Positions 1-282.
ModBase	Search...
Protein family/group databases
Allergome	822. Hal d 1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000533. Tropomyosin. [Graphical view]
Pfam	PF00261. Tropomyosin. 1 hit. [Graphical view]
PRINTS	PR00194. TROPOMYOSIN.
PROSITE	PS00326. TROPOMYOSIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TPM_HALDV

Accession

Primary (citable) accession number: Q9GZ71

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	March 1, 2001
Last modified:	March 8, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)