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Q9GTW9 (GLK1_TRIVA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase 1

EC=2.7.1.2
Alternative name(s):
Glucose kinase 1
Hexokinase-1
Gene names
Name:GK1
OrganismTrichomonas vaginalis
Taxonomic identifier5722 [NCBI]
Taxonomic lineageEukaryotaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate.

Subunit structure

Monomer.

Post-translational modification

The N-terminus is blocked.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processcarbohydrate phosphorylation

Inferred from electronic annotation. Source: GOC

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 375375Glucokinase 1
PRO_0000215151

Regions

Nucleotide binding25 – 306ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q9GTW9 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 229F76B24637BE21

FASTA37541,585
        10         20         30         40         50         60 
MFSIDLIQQI KEWKRGSTLP ICLGCDVGGS GLRVRLSDFH DSAKYVDLGH AKAQKTAELL 

        70         80         90        100        110        120 
KVLEDLQQKI LQVEPTTVCL GAAIAVAGPI KNNTVILTNW KGPAEERTLS ITQLPKGLFP 

       130        140        150        160        170        180 
KDRSYFLNDL EAGAYGVIAA YEQSILEENF VQLFTDRAPT GPILAKGRTA VLAMGSGLGA 

       190        200        210        220        230        240 
ALVTRTPLLK NPLVLPTELG HLQIAPNMAT HKYFQDEQEL IQHISDHYYG GKLDPEYEDI 

       250        260        270        280        290        300 
CSGRGLQLAF QFYHKKLTGE VLPLEQIDAG DVAKKAIAGE KDAYNALRAH YIFYLRAAKA 

       310        320        330        340        350        360 
IATSLSCESC VLSLDNQVKN HPFVMKIAKE LEEEFYEFIR PDWMTSVRVY SQKSILNFNI 

       370 
LGTDYMAHAI ANKPQ 

« Hide

References

[1]"Evolutionary relationships of the glucokinase from the amitochondriate protist, Trichomonas vaginalis."
Wu G., Henze K., Mueller M.
Gene 264:265-271(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE, CHARACTERIZATION.
Strain: ATCC 30001 / NIH-C1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF248652 Genomic DNA. Translation: AAG17616.1.

3D structure databases

ProteinModelPortalQ9GTW9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG318218.

Family and domain databases

InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLK1_TRIVA
AccessionPrimary (citable) accession number: Q9GTW9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families