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Protein

Probable glucokinase 2

Gene

GK2

Organism
Trichomonas vaginalis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi27 – 326ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glucokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucokinase 2 (EC:2.7.1.2)
Alternative name(s):
Glucose kinase 2
Hexokinase-2
Gene namesi
Name:GK2
OrganismiTrichomonas vaginalis
Taxonomic identifieri5722 [NCBI]
Taxonomic lineageiEukaryotaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Probable glucokinase 2PRO_0000215152Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9GTW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.Curated

Phylogenomic databases

eggNOGiNOG318218.

Family and domain databases

InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9GTW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDIELVKKI NDWKVSEDGA LPICIGCDVG GSGLRVRISS FNDSEKYVDL
60 70 80 90 100
GHAKAKCTKQ LVDVLADLEQ KIKQVNDKFV CLGAAIAVAG PIKAGTVILT
110 120 130 140 150
NWQGEPAVRT LTLKDLPQKI FPKDRSVFLN DLEAGAYGVI AAADKDILEQ
160 170 180 190 200
NFVQLFQDKA PKGPVLANGR TAVLAMGSGL GAALVVRTPL LKNPLVLPTE
210 220 230 240 250
LGHVQIAPNM KEHKNFKQER ELIQHISNHY YKGELDPEYE DICSGRGLPL
260 270 280 290 300
AYQFYHQKKT GELLPVEQID AGEVAKKAMD GEEDAVDALK AHYIFYLRAA
310 320 330 340 350
KAIATSLSCE SCVLSLDNQV KNHPFVMKIM KELEDEFYEF IRPDWMNGLR
360 370
VYSQKSILNF NILGTDYMAH AIANKPE
Length:377
Mass (Da):41,773
Last modified:March 1, 2001 - v1
Checksum:iA4270820B97919DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF248653 Genomic DNA. Translation: AAG17617.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF248653 Genomic DNA. Translation: AAG17617.1.

3D structure databases

ProteinModelPortaliQ9GTW8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG318218.

Family and domain databases

InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Evolutionary relationships of the glucokinase from the amitochondriate protist, Trichomonas vaginalis."
    Wu G., Henze K., Mueller M.
    Gene 264:265-271(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 30001 / NIH-C1.

Entry informationi

Entry nameiGLK2_TRIVA
AccessioniPrimary (citable) accession number: Q9GTW8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: March 1, 2001
Last modified: October 1, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.