Q9GRF3 (Q9GRF3_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lysozyme P, putative EMBL EAT44944.1

Submitted name:
Putative lysozyme EMBL CAC19819.1

Gene names

ORF Names:

AAEL003723, AaeL_AAEL003723 EMBL EAT44944.1

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) EMBL CAC19819.1

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	148 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 22 family. RuleBase RU004440

Ontologies

Keywords
Domain	Signal EMBL CAC19819.1
PTM	Disulfide bond SAAS SAAS000974
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	lysozyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential EMBL CAC19819.1
	Chain	24 – 148	125	lysozyme EMBL CAC19819.1		PRO_5000066286

Sequences

	Sequence		Length	Mass (Da)
	Q9GRF3 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 8C07C675470F1FFD	FASTA	148	16,965
	10 20 30 40 50 60 MRNLNLLIVL VGLFALLSVN VEAKKFDKCS LAKALLAQGF NKADLRNWVC LVQNESGMDT 70 80 90 100 110 120 NKKNNNRNGS TDWGLFQIND RYWCDPQDKK KKTSNECKIK CSELLKDDIS KASACVKKIY 130 140 KRHGYRAWYG WLNRCEGKAL PDLSKCKL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed: 17510324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.
[2]	"Immune activation upregulates lysozyme gene expression in Aedes aegypti mosquito cell culture." Gao Y., Fallon A.M. Insect Mol. Biol. 9:553-558(2000) [PubMed: 11122464] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ290428 mRNA. Translation: CAC19819.1. CH477280 Genomic DNA. Translation: EAT44944.1.
RefSeq	XP_001664050.1. XM_001664000.1.
UniGene	Aae.5811.
3D structure databases
HSSP	HSSP built from PDB template 1GD6 based on UniProtKB P48816.
ProteinModelPortal	Q9GRF3.
ModBase	Search...
Protein family/group databases
CAZy	GH22. Glycoside Hydrolase Family 22.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL003723-RA; AAEL003723-PA; AAEL003723.
GeneID	5578841.
KEGG	aag:AaeL_AAEL003723.
VectorBase	AAEL003723. Aedes aegypti.
Phylogenomic databases
eggNOG	meNOG18916.
GeneTree	EMGT00050000002113.
InParanoid	Q9GRF3.
OMA	RYSIACA.
OrthoDB	EOG4CNP7F.
PhylomeDB	Q9GRF3.
Family and domain databases
InterPro	IPR001916. Glyco_hydro_22. IPR019799. Glyco_hydro_22_CS. IPR000974. Glyco_hydro_22_lys. IPR023346. Lysozyme-like_dom. [Graphical view]
KO	K13915.
Pfam	PF00062. Lys. 1 hit. [Graphical view]
PRINTS	PR00137. LYSOZYME. PR00135. LYZLACT.
SMART	SM00263. LYZ1. 1 hit. [Graphical view]
SUPFAM	SSF53955. SSF53955. 1 hit.
PROSITE	PS00128. LACTALBUMIN_LYSOZYME_1. 1 hit. PS51348. LACTALBUMIN_LYSOZYME_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9GRF3_AEDAE

Accession

Primary (citable) accession number: Q9GRF3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)