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Protein
Submitted name:

IAG-nucleoside hydrolase

Gene
N/A
Organism
Trypanosoma vivax (Duttonella vivax)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi10CalciumCombined sources1
Binding sitei10SubstrateCombined sources1
Metal bindingi15CalciumCombined sources1
Binding sitei83SubstrateCombined sources1
Metal bindingi137Calcium; via carbonyl oxygenCombined sources1
Binding sitei186SubstrateCombined sources1
Sitei260Important for catalytic activityCombined sources1
Metal bindingi261CalciumCombined sources1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-15858.
BRENDAi3.2.2.1. 6532.
SABIO-RKQ9GPQ4.

Names & Taxonomyi

Protein namesi
Submitted name:
IAG-nucleoside hydrolaseImported
OrganismiTrypanosoma vivax (Duttonella vivax)Imported
Taxonomic identifieri5699 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaDuttonella

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL6134.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi85Interchain (with C-248)Combined sources
Disulfide bondi248Interchain (with C-85)Combined sources

Interactioni

Chemistry databases

BindingDBiQ9GPQ4.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1HOZX-ray1.60A/B2-327[»]
1HP0X-ray2.10A/B2-327[»]
1KICX-ray1.60A/B2-327[»]
1KIEX-ray2.00A/B2-327[»]
1R4FX-ray2.30A/B2-327[»]
2FF1X-ray2.07A/B2-327[»]
2FF2X-ray2.20A/B2-327[»]
3B9GX-ray1.40A/B2-244[»]
A/B258-327[»]
3EPWX-ray1.30A/B2-327[»]
3EPXX-ray1.85A/B2-327[»]
ProteinModelPortaliQ9GPQ4.
SMRiQ9GPQ4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9GPQ4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 305IU_nuc_hydroInterPro annotationAdd BLAST303

Family and domain databases

Gene3Di3.90.245.10. 1 hit.
InterProiIPR023186. Inosine/uridine_hydrolase.
IPR001910. Inosine/uridine_hydrolase_dom.
[Graphical view]
PANTHERiPTHR12304. PTHR12304. 1 hit.
PfamiPF01156. IU_nuc_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53590. SSF53590. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9GPQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKNVVLDHD GNLDDFVAMV LLASNTEKVR LIGALCTDAD CFVENGFNVT
60 70 80 90 100
GKIMCLMHNN MNLPLFPIGK SAATAVNPFP KEWRCLAKNM DDMPILNIPE
110 120 130 140 150
NVELWDKIKA ENEKYEGQQL LADLVMNSEE KVTICVTGPL SNVAWCIDKY
160 170 180 190 200
GEKFTSKVEE CVIMGGAVDV RGNVFLPSTD GTAEWNIYWD PASAKTVFGC
210 220 230 240 250
PGLRRIMFSL DSTNTVPVRS PYVQRFGEQT NFLLSILVGT MWAMCTHCEL
260 270 280 290 300
LRDGDGYYAW DALTAAYVVD QKVANVDPVP IDVVVDKQPN EGATVRTDAE
310 320
KYPLTFVARN PEAEFFLDML LRSARAC
Length:327
Mass (Da):36,331
Last modified:March 1, 2001 - v1
Checksum:i034F9833FF6C2825
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF311701 mRNA. Translation: AAG38561.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF311701 mRNA. Translation: AAG38561.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1HOZX-ray1.60A/B2-327[»]
1HP0X-ray2.10A/B2-327[»]
1KICX-ray1.60A/B2-327[»]
1KIEX-ray2.00A/B2-327[»]
1R4FX-ray2.30A/B2-327[»]
2FF1X-ray2.07A/B2-327[»]
2FF2X-ray2.20A/B2-327[»]
3B9GX-ray1.40A/B2-244[»]
A/B258-327[»]
3EPWX-ray1.30A/B2-327[»]
3EPXX-ray1.85A/B2-327[»]
ProteinModelPortaliQ9GPQ4.
SMRiQ9GPQ4.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiQ9GPQ4.
ChEMBLiCHEMBL6134.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-15858.
BRENDAi3.2.2.1. 6532.
SABIO-RKQ9GPQ4.

Miscellaneous databases

EvolutionaryTraceiQ9GPQ4.

Family and domain databases

Gene3Di3.90.245.10. 1 hit.
InterProiIPR023186. Inosine/uridine_hydrolase.
IPR001910. Inosine/uridine_hydrolase_dom.
[Graphical view]
PANTHERiPTHR12304. PTHR12304. 1 hit.
PfamiPF01156. IU_nuc_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53590. SSF53590. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9GPQ4_TRYVI
AccessioniPrimary (citable) accession number: Q9GPQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.