Q9GNF7 (Q9GNF7_DROSI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GD25630 EMBL EDX07187.1

Submitted name:
Hexokinase-C EMBL AAG22942.1

Gene names

Name:	Hex-C EMBL AAG22942.1 FlyBase FBgn0021123
Synonyms:	Dsim\GD25630 EMBL EDX07187.1
ORF Names:	Dsim_GD25630 EMBL EDX07187.1, GD11104 FlyBase FBgn0021123, GD25630 FlyBase FBgn0196916

Organism

Drosophila simulans (Fruit fly) [Complete proteome] EMBL AAG22942.1

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	454 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
Biological process	Glycolysis SAAS SAAS001312
Ligand	ATP-binding SAAS SAAS001312 Nucleotide-binding
Molecular function	Kinase SAAS SAAS001312 EMBL AAG22942.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW kinase activity Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9GNF7 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 410AF39A159EFF6B	FASTA	454	50,767
	10 20 30 40 50 60 MLDAEVRELM QPFVLSDYQV QEVYSRFCLE VARGLKRSTH PQANVKCFPT YVQDLPTGDE 70 80 90 100 110 120 MGKYLALDLG GTNFRVLLVS LKGHHDATVD SQIYAVPKDL MVGPGVDLFD HIAGCLAKFV 130 140 150 160 170 180 EKHDMKTAYL PLGFTFSFPC VQQGLKEGIL VRWTKGFDCA GVEGEDVGRM LHEAIQRRGD 190 200 210 220 230 240 ADIAVVAILN DTTGTLMSCA HRNADCRVGV IVGTGCNACY VEDVENVDLL RADFKKTKRS 250 260 270 280 290 300 VIVNAEWGAF GEGGQLDFVR TEYDREIDEK SLNRSEQLFE KMTAGMYLGN LVRLVLLRAL 310 320 330 340 350 360 ERKLIFKQSS RRPEFASVLQ RNEEVFETRY ISEIEDDSFP EFASTRKIVK NLFGLEKASV 370 380 390 400 410 420 EDCQTLRYIC ECVAKRAATL VAIGVSGLVN RTSNRRVIVG MDGSVYRYHP KFDAYMRQTL 430 440 450 QKLVKADKEW DIMLSEDGSG RGAALVAAVA SKTK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Contrasting molecular population genetics of four hexokinases in Drosophila melanogaster, D. simulans and D. yakuba." Duvernell D.D., Eanes W.F. Genetics 156:1191-1201(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CT96_2s EMBL AAG22930.1, CT96_5s EMBL AAG22931.1, CT96_6s EMBL AAG22932.1, DPF96_3s EMBL AAG22929.1, GA96_2s EMBL AAG22937.1, GA96_4s EMBL AAG22938.1, GA96_5s EMBL AAG22939.1, HFL97_1s EMBL AAG22940.1, HFL97_2s EMBL AAG22941.1, HFL97_4s EMBL AAG22942.1, VA96_5s EMBL AAG22933.1, VA96_6s EMBL AAG22934.1, VA96_7s EMBL AAG22935.1 and VA96_8s EMBL AAG22936.1.
[2]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Mixed EMBL EDX07187.1.
[3]	FlyBase Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDX07187.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF257623 Genomic DNA. Translation: AAG22929.1. AF257624 Genomic DNA. Translation: AAG22930.1. AF257625 Genomic DNA. Translation: AAG22931.1. AF257626 Genomic DNA. Translation: AAG22932.1. AF257627 Genomic DNA. Translation: AAG22933.1. AF257628 Genomic DNA. Translation: AAG22934.1. AF257629 Genomic DNA. Translation: AAG22935.1. AF257630 Genomic DNA. Translation: AAG22936.1. AF257631 Genomic DNA. Translation: AAG22937.1. AF257632 Genomic DNA. Translation: AAG22938.1. AF257633 Genomic DNA. Translation: AAG22939.1. AF257634 Genomic DNA. Translation: AAG22940.1. AF257635 Genomic DNA. Translation: AAG22941.1. AF257636 Genomic DNA. Translation: AAG22942.1. CM000362 Genomic DNA. Translation: EDX07187.1.
RefSeq	XP_002081602.1. XM_002081566.1.
UniGene	Dsi.5327.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0225540; FBpp0224032; FBgn0196916.
GeneID	6734594.
KEGG	dsi:Dsim_GD25630.
Organism-specific databases
FlyBase	FBgn0196916. Dsim\GD25630. FBgn0021123. Dsim\Hex-C.
Phylogenomic databases
KO	K00844.
OrthoDB	EOG4B5MMF.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
ProtoNet	Search...

Entry information

Entry name

Q9GNF7_DROSI

Accession

Primary (citable) accession number: Q9GNF7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 29, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)