true2004-08-162024-01-24101GALT9_MACFAIsolation of full-length cDNA clones from macaque brain cDNA libraries.Osada N.Hida M.Kusuda J.Tanuma R.Iseki K.Hirai M.Terao K.Suzuki Y.Sugano S.Hashimoto K.2000-10EMBL/GenBank/DDBJNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]Parietal cortexCarbohydrate-Binding Module Family 13Glycosyltransferase Family 271 site, No reported glycansEukaryotapp-GalNAc-TRICINGalNAc-TGlyco_trans_2-likeNucleotide-diphossugar_transRicin_B-like_lectinsRicin_B_lectinN-ACETYLGALACTOSAMINYLTRANSFERASEPOLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9Glycos_transf_2Ricin_B_lectinRICINNucleotide-diphospho-sugar transferasesRicin B-like lectinsRICIN_B_LECTINPolypeptide N-acetylgalactosaminyltransferase 92.4.1.41Polypeptide GalNAc transferase 9GalNAc-T9pp-GaNTase 9Protein-UDP acetylgalactosaminyltransferase 9UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9GALNT9QnpA-13140Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3.There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.Polypeptide N-acetylgalactosaminyltransferase 9683181606Cytoplasmic6Helical; Signal-anchor for type II membrane protein729Lumenal30Ricin B-type lectin467603Disordered4362Catalytic subdomain A153264Catalytic subdomain B321383194225248250380388N-linked (GlcNAc...) asparagine463144375366445480496528543570590substrate2001-03-0116831891b789e6f530e77f90596fe615ddc540MAVARKIRTLLTVNILVFVGIVLFSVYCRLQGRSQELVRPLSGGCRPRPATPAPGSPLRSGGPRAVVAGRAELVLKGQLPAEPCSPGRLMVPEAEAEAQGGLAATLRDDGQEAEGKYEEYGYNAQLSDRISLDRSIPDYRPRKCRHMSYAQDLPQVSVVFIFVNEALSVILRSVHSVVNHTPSQLLKEVILVDDNSDNVELKFNLDQYVNKRYPGLVKIVRNSRREGLIRARLQGWKAATAPVVGFFDAHVEFNTGWAEPALSRIREDRRRIVLPAIDNIKYSTFEVQQYANAAHGYNWGLWCMYIIPPQDWLDRGDESAPIRTPAMIGCSFVVDREYFGDIGLLDPGMEVYGGENVELGMRVWQCGGSMEVLPCSRVAHIERTRKPYNNDIDYYAKRNALRAAEVWMDDFKSHVYMAWNIPMTNPGVDFGDVSERLALRQRLKCRSFKWYLENVYPEMRIYNNTLTYGEVRNSKASGYCLDQGAEDGDRAILYPCHGMSSQLVRYSADGLLQLGPLGSTAFLPDSKCLVDDGRGRTPTLRKCEDVARPTQRLWDFTQSGPIVSRATGRCLEVEMSKDANFGLRLVVQRCSGQKWMIRNWIKHARHtruetruetruetruetrue