Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Leukemia inhibitory factor

Gene

LIF

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-6788467. IL-6-type cytokine receptor ligand interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
Leukemia inhibitory factorImported
Gene namesi
Name:LIFImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501121242023 – 202Sequence analysisAdd BLAST180

Expressioni

Gene expression databases

BgeeiENSSSCG00000009996.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000010668.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410ITBQ. Eukaryota.
ENOG410YVPP. LUCA.
GeneTreeiENSGT00390000000059.
HOGENOMiHOG000059647.
HOVERGENiHBG006267.
KOiK05419.
OMAiKYHVAHV.
OrthoDBiEOG091G0HWD.
TreeFamiTF336245.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR003624. Leukemia_IF.
IPR001581. Leukemia_IF/oncostatin.
IPR019827. Leukemia_IF/oncostatin_CS.
PANTHERiPTHR10633. PTHR10633. 1 hit.
PfamiView protein in Pfam
PF01291. LIF_OSM. 1 hit.
PRINTSiPR01883. LEUKAEMIAIF.
SMARTiView protein in SMART
SM00080. LIF_OSM. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00590. LIF_OSM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9GKZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLAAGVVP LLLVLHWKHG AGSPLSITPV NATCATRHPC HSNLMNQIKN
60 70 80 90 100
QLAQLNSSAN ALFILYYTAQ GEPFPNNLDK LCGPNVTNFP PFHANGTEKA
110 120 130 140 150
RLVELYRIIA YLGASLGNIT RDQRSLNPGA VNLHSKLNAT ADSMRGLLSN
160 170 180 190 200
VLCRLCNKYH VAHVDVAYGP DTSGKDVFQK KKLGCQLLGK YKQVISVLAR

AF
Length:202
Mass (Da):21,989
Last modified:March 1, 2001 - v1
Checksum:i09875132E5C8C735
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000096 Genomic DNA. No translation available.
AY585336 mRNA. Translation: AAS98213.1.
AJ296176 Genomic DNA. Translation: CAC14463.1.
PIRiS23069.
RefSeqiNP_999567.1. NM_214402.2.
XP_005670842.1. XM_005670785.2.
XP_013838479.1. XM_013983025.1.
XP_013838480.1. XM_013983026.1.
UniGeneiSsc.52878.

Genome annotation databases

EnsembliENSSSCT00000044908; ENSSSCP00000036194; ENSSSCG00000040961.
ENSSSCT00000054307; ENSSSCP00000041937; ENSSSCG00000040961.
GeneIDi399503.
KEGGissc:399503.

Similar proteinsi

Entry informationi

Entry nameiQ9GKZ8_PIG
AccessioniPrimary (citable) accession number: Q9GKZ8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 22, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported