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Protein
Submitted name:

Leukemia inhibitory factor

Gene

LIF

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-6788467 IL-6-type cytokine receptor ligand interactions

Names & Taxonomyi

Protein namesi
Submitted name:
Leukemia inhibitory factorImported
Gene namesi
Name:LIFImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501410810223 – 202Sequence analysisAdd BLAST180

Expressioni

Gene expression databases

BgeeiENSSSCG00000009996

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000010668

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410ITBQ Eukaryota
ENOG410YVPP LUCA
GeneTreeiENSGT00390000000059
HOGENOMiHOG000059647
HOVERGENiHBG006267
KOiK05419
OMAiKYHVAHV
OrthoDBiEOG091G0HWD
TreeFamiTF336245

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR003624 Leukemia_IF
IPR001581 Leukemia_IF/oncostatin
IPR019827 Leukemia_IF/oncostatin_CS
PANTHERiPTHR10633 PTHR10633, 1 hit
PfamiView protein in Pfam
PF01291 LIF_OSM, 1 hit
PRINTSiPR01883 LEUKAEMIAIF
SMARTiView protein in SMART
SM00080 LIF_OSM, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00590 LIF_OSM, 1 hit

Sequencei

Sequence statusi: Complete.

Q9GKZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLAAGVVP LLLVLHWKHG AGSPLSITPV NATCATRHPC HSNLMNQIKN
60 70 80 90 100
QLAQLNSSAN ALFILYYTAQ GEPFPNNLDK LCGPNVTNFP PFHANGTEKA
110 120 130 140 150
RLVELYRIIA YLGASLGNIT RDQRSLNPGA VNLHSKLNAT ADSMRGLLSN
160 170 180 190 200
VLCRLCNKYH VAHVDVAYGP DTSGKDVFQK KKLGCQLLGK YKQVISVLAR

AF
Length:202
Mass (Da):21,989
Last modified:March 1, 2001 - v1
Checksum:i09875132E5C8C735
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000096 Genomic DNA No translation available.
AY585336 mRNA Translation: AAS98213.1
AJ296176 Genomic DNA Translation: CAC14463.1
PIRiS23069
RefSeqiNP_999567.1, NM_214402.2
XP_005670842.1, XM_005670785.2
XP_013838479.1, XM_013983025.1
XP_013838480.1, XM_013983026.1
UniGeneiSsc.52878

Genome annotation databases

EnsembliENSSSCT00000044908; ENSSSCP00000036194; ENSSSCG00000040961
ENSSSCT00000054307; ENSSSCP00000041937; ENSSSCG00000040961
GeneIDi399503
KEGGissc:399503

Similar proteinsi

Entry informationi

Entry nameiQ9GKZ8_PIG
AccessioniPrimary (citable) accession number: Q9GKZ8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health