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Protein
Submitted name:

Fas antigen APO-1/CD95

Gene

fas

Organism
Macaca assamensis (Assam macaque) (Assamese macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Fas antigen APO-1/CD95Imported
Gene namesi
Name:fasImported
OrganismiMacaca assamensis (Assam macaque) (Assamese macaque)Imported
Taxonomic identifieri9551 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500432648526 – 331Sequence analysisAdd BLAST306

Structurei

3D structure databases

ProteinModelPortaliQ9GK36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 127TNFR-CysInterPro annotationAdd BLAST44
Repeati84 – 127TNFR-CysPROSITE-ProRule annotationAdd BLAST44
Domaini128 – 165TNFR-CysInterPro annotationAdd BLAST38
Repeati128 – 165TNFR-CysPROSITE-ProRule annotationAdd BLAST38
Domaini226 – 310DeathInterPro annotationAdd BLAST85

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG004091.

Family and domain databases

CDDicd08316. Death_FAS_TNFRSF6. 1 hit.
cd10579. TNFRSF6. 1 hit.
Gene3Di1.10.533.10. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR033998. TNFRSF6_death.
IPR033999. TNFRSF6_N.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
PRINTSiPR01680. TNFACTORR6.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00208. TNFR. 2 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9GK36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGTWTLLPL VLTSVVRLLS KCVNAQVTDV SSKGFELRKI VTTIETQNLE
60 70 80 90 100
GLHHEGQFCR NPCPPGERKA RDCTVNEDEP DCVPCQEGKE YTDKGHLSSK
110 120 130 140 150
CRRCRLCDEG HGLEVEINCT RTQNTKCRCK PNFFCNSAVC EHCDPRIKCK
160 170 180 190 200
HGIIEECTLT SNTKCKEEDS RSDLPWLCLL LLLIPPIVYV VIKKACRKHR
210 220 230 240 250
KENQGPHEST TLNPETAINL SDVDLSKYIT TIAGAMTLSQ VKDFVRKNGV
260 270 280 290 300
SEAKIDEIKN DNVQDTAEQK VQPLRNWYQL HGKKDACDTL IKGLKTADLC
310 320 330
TLAEKIHAVI LKDITSDTEN SNFGNEVQNL V
Length:331
Mass (Da):37,168
Last modified:March 1, 2001 - v1
Checksum:iCE58DB046C67834F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF326208 mRNA. Translation: AAG49382.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF326208 mRNA. Translation: AAG49382.1.

3D structure databases

ProteinModelPortaliQ9GK36.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG004091.

Family and domain databases

CDDicd08316. Death_FAS_TNFRSF6. 1 hit.
cd10579. TNFRSF6. 1 hit.
Gene3Di1.10.533.10. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR033998. TNFRSF6_death.
IPR033999. TNFRSF6_N.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
PRINTSiPR01680. TNFACTORR6.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00208. TNFR. 2 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9GK36_MACAS
AccessioniPrimary (citable) accession number: Q9GK36
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 15, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.