ID   Q9GJT3_SAGOE            Unreviewed;       336 AA.
AC   Q9GJT3;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 111.
DE   SubName: Full=CDw150 {ECO:0000313|EMBL:AAG02017.1};
DE   SubName: Full=Signaling lymphocytic activation molecule 1 {ECO:0000313|EMBL:AAG18445.1};
GN   Name=CDw150 {ECO:0000313|EMBL:AAG18445.1};
OS   Saguinus oedipus (Cotton-top tamarin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Saguinus.
OX   NCBI_TaxID=9490 {ECO:0000313|EMBL:AAG18445.1};
RN   [1] {ECO:0000313|EMBL:AAG02017.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Lymphoblastoid {ECO:0000313|EMBL:AAG02017.1};
RX   PubMed=10972291; DOI=10.1038/35022579;
RA   Tatsuo H., Ono N., Tanaka K., Yanagi Y.;
RT   "SLAM (CDw150) is a cellular receptor for measles virus.";
RL   Nature 406:893-897(2000).
RN   [2] {ECO:0000313|EMBL:AAG18445.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11145884; DOI=10.1006/viro.2000.0711;
RA   Hsu E.C., Iorio C., Sarangi F., Khine A.A., Richardson C.D.;
RT   "CDw150(SLAM) is a receptor for a lymphotropic strain of measles virus and
RT   may account for the immunosuppressive properties of this virus.";
RL   Virology 279:9-21(2001).
RN   [3] {ECO:0007829|PDB:3ALW, ECO:0007829|PDB:3ALX}
RP   X-RAY CRYSTALLOGRAPHY (3.15 ANGSTROMS) OF 26-140, AND DISULFIDE BONDS.
RX   PubMed=21217702; DOI=10.1038/nsmb.1969;
RA   Hashiguchi T., Ose T., Kubota M., Maita N., Kamishikiryo J., Maenaka K.,
RA   Yanagi Y.;
RT   "Structure of the measles virus hemagglutinin bound to its cellular
RT   receptor SLAM.";
RL   Nat. Struct. Mol. Biol. 18:135-141(2011).
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DR   EMBL; AF257239; AAG02017.1; -; mRNA.
DR   EMBL; AF302038; AAG18445.1; -; mRNA.
DR   PDB; 3ALW; X-ray; 3.55 A; A=24-140.
DR   PDB; 3ALX; X-ray; 3.15 A; A/B/C/D=24-140.
DR   PDB; 3ALZ; X-ray; 4.51 A; B=1-140.
DR   PDBsum; 3ALW; -.
DR   PDBsum; 3ALX; -.
DR   PDBsum; 3ALZ; -.
DR   AlphaFoldDB; Q9GJT3; -.
DR   SMR; Q9GJT3; -.
DR   DIP; DIP-59071N; -.
DR   IntAct; Q9GJT3; 1.
DR   EvolutionaryTrace; Q9GJT3; -.
DR   GO; GO:0009986; C:cell surface; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0046649; P:lymphocyte activation; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR010407; Sig_lymph_act_molc_N.
DR   PANTHER; PTHR12080; SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE; 1.
DR   PANTHER; PTHR12080:SF49; SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE; 1.
DR   Pfam; PF06214; SLAM; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3ALW, ECO:0007829|PDB:3ALX};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..336
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007716823"
FT   TRANSMEM        240..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          144..223
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DISULFID        32..132
FT                   /evidence="ECO:0007829|PDB:3ALW, ECO:0007829|PDB:3ALX"
SQ   SEQUENCE   336 AA;  37717 MW;  5D5B4ED7FDAEA764 CRC64;
     MDPKGLFSLT FVLFLSLAFE PSYGTGGRMM NCPKIVQQLG SDVLLPLTHE RINTSMNKSI
     HIVVTMAKSL ENSVENKIVS LDPSEAGPPR YLKDRYRFYL ENLSLAIRES TKKDEGWYFM
     TLEKNISVQR FCLHLKLYEQ VSTPEIKVLN KTQENGTCTL ILGCIVKKGD HVAYSWSEKA
     GTHPLSPANS SHLLSLTLGP QHAKNIYVCT VSNPISNSSQ DFIPWLRCRQ EPSETNIWPV
     YAWLSLAGVI IILIVIAIML LRRRGKTDHY QTTTEKKNLT IYAQVQKPGP LQKKLDSFPA
     QDPCTTIYVA ATEPVPEPVQ ETNSITVYAS VTLPES
//