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Q9FZG4

- HXKL1_ARATH

UniProt

Q9FZG4 - HXKL1_ARATH

Protein

Hexokinase-like 1 protein

Gene

At1g47840

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 2 (31 Oct 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + D-hexose = ADP + D-hexose 6-phosphate.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi104 – 1096ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. fructokinase activity Source: TAIR
    3. glucokinase activity Source: TAIR

    GO - Biological processi

    1. carbohydrate phosphorylation Source: GOC
    2. glucose 6-phosphate metabolic process Source: GOC
    3. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G47840-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hexokinase-like 1 protein (EC:2.7.1.1)
    Gene namesi
    Ordered Locus Names:At1g47840
    ORF Names:T2E6.5
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G47840.

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 493493Hexokinase-like 1 proteinPRO_0000259633Add
    BLAST

    Proteomic databases

    PaxDbiQ9FZG4.
    PRIDEiQ9FZG4.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9FZG4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FZG4.
    SMRiQ9FZG4. Positions 30-488.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini45 – 244200Hexokinase type-1Add
    BLAST
    Domaini250 – 489240Hexokinase type-2Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni175 – 20127Glucose-bindingSequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the hexokinase family.Curated
    Contains 1 hexokinase type-1 domain.Curated
    Contains 1 hexokinase type-2 domain.Curated

    Phylogenomic databases

    eggNOGiCOG5026.
    HOGENOMiHOG000162670.
    InParanoidiQ9FZG4.
    KOiK00844.
    OMAiQKDCATP.
    PhylomeDBiQ9FZG4.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9FZG4-1 [UniParc]FASTAAdd to Basket

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    MSLMFSSPVV TPALGSFTFS SRPRSNYIVM SAVRSNSAST CPILTKFQKD    50
    CATPTPYLRN VANAIADDMR DGLAVEGGGD LEMILTFVDA LPSGNEEGLF 100
    YALDLGGTNF RVRSVQLGGK KERVLATESE QISISQKLMI GTSEELFGFI 150
    ASKLANFVAK EKPGRFLLEE GRKRELGFTF SFPVKQTSID SGTLSKWTKG 200
    FKVSGMEGKN VVACLNEAME AHGLDMRVSA LVNDGVGTLA GARYWDEDVM 250
    VGVILGTGTN ACYVEQKHAI PKLRSKSSSG TTIINTEWGG FSKILPQTIF 300
    DLEMDETSLN PGEHLYEKMI SGMYLGEIVR RVLLHMCETS DLFGHFAPAK 350
    LSTPLALRTE HLCKMQEDNT DDLRDVGSIL YDFLDVEANM NARRRVVEVC 400
    DTVVKRGGRL AGAGIVAILE KIEKDTKRMG SGKRTVVAMD GALYEKYPQY 450
    RQYMQDALVE LLGHKLASHV AIKHTKDVSG LGAALLAATN SIY 493
    Length:493
    Mass (Da):53,880
    Last modified:October 31, 2006 - v2
    Checksum:i485C0BA6FBCDECF9
    GO

    Sequence cautioni

    The sequence AAF99786.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012463 Genomic DNA. Translation: AAF99786.1. Sequence problems.
    CP002684 Genomic DNA. Translation: AEE32221.1.
    BT030472 mRNA. Translation: ABP88126.1.
    RefSeqiNP_175220.2. NM_103682.3.
    UniGeneiAt.38526.

    Genome annotation databases

    EnsemblPlantsiAT1G47840.1; AT1G47840.1; AT1G47840.
    GeneIDi841200.
    KEGGiath:AT1G47840.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012463 Genomic DNA. Translation: AAF99786.1 . Sequence problems.
    CP002684 Genomic DNA. Translation: AEE32221.1 .
    BT030472 mRNA. Translation: ABP88126.1 .
    RefSeqi NP_175220.2. NM_103682.3.
    UniGenei At.38526.

    3D structure databases

    ProteinModelPortali Q9FZG4.
    SMRi Q9FZG4. Positions 30-488.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9FZG4.
    PRIDEi Q9FZG4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G47840.1 ; AT1G47840.1 ; AT1G47840 .
    GeneIDi 841200.
    KEGGi ath:AT1G47840.

    Organism-specific databases

    TAIRi AT1G47840.

    Phylogenomic databases

    eggNOGi COG5026.
    HOGENOMi HOG000162670.
    InParanoidi Q9FZG4.
    KOi K00844.
    OMAi QKDCATP.
    PhylomeDBi Q9FZG4.

    Enzyme and pathway databases

    BioCyci ARA:AT1G47840-MONOMER.

    Gene expression databases

    Genevestigatori Q9FZG4.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Arabidopsis ORF clones."
      Bautista-Mercan V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.
      Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiHXKL1_ARATH
    AccessioniPrimary (citable) accession number: Q9FZG4
    Secondary accession number(s): A4VCN1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 80 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3