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Q9FZG4

- HXKL1_ARATH

UniProt

Q9FZG4 - HXKL1_ARATH

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Protein
Hexokinase-like 1 protein
Gene
At1g47840, T2E6.5
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi104 – 1096ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: TAIR
  3. glucokinase activity Source: TAIR
Complete GO annotation...

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. glucose 6-phosphate metabolic process Source: GOC
  3. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G47840-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hexokinase-like 1 protein (EC:2.7.1.1)
Gene namesi
Ordered Locus Names:At1g47840
ORF Names:T2E6.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G47840.

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Hexokinase-like 1 protein
PRO_0000259633Add
BLAST

Proteomic databases

PaxDbiQ9FZG4.
PRIDEiQ9FZG4.

Expressioni

Gene expression databases

GenevestigatoriQ9FZG4.

Structurei

3D structure databases

ProteinModelPortaliQ9FZG4.
SMRiQ9FZG4. Positions 30-488.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini45 – 244200Hexokinase type-1
Add
BLAST
Domaini250 – 489240Hexokinase type-2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni175 – 20127Glucose-binding Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
InParanoidiQ9FZG4.
KOiK00844.
OMAiQKDCATP.
PhylomeDBiQ9FZG4.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FZG4-1 [UniParc]FASTAAdd to Basket

« Hide

MSLMFSSPVV TPALGSFTFS SRPRSNYIVM SAVRSNSAST CPILTKFQKD    50
CATPTPYLRN VANAIADDMR DGLAVEGGGD LEMILTFVDA LPSGNEEGLF 100
YALDLGGTNF RVRSVQLGGK KERVLATESE QISISQKLMI GTSEELFGFI 150
ASKLANFVAK EKPGRFLLEE GRKRELGFTF SFPVKQTSID SGTLSKWTKG 200
FKVSGMEGKN VVACLNEAME AHGLDMRVSA LVNDGVGTLA GARYWDEDVM 250
VGVILGTGTN ACYVEQKHAI PKLRSKSSSG TTIINTEWGG FSKILPQTIF 300
DLEMDETSLN PGEHLYEKMI SGMYLGEIVR RVLLHMCETS DLFGHFAPAK 350
LSTPLALRTE HLCKMQEDNT DDLRDVGSIL YDFLDVEANM NARRRVVEVC 400
DTVVKRGGRL AGAGIVAILE KIEKDTKRMG SGKRTVVAMD GALYEKYPQY 450
RQYMQDALVE LLGHKLASHV AIKHTKDVSG LGAALLAATN SIY 493
Length:493
Mass (Da):53,880
Last modified:October 31, 2006 - v2
Checksum:i485C0BA6FBCDECF9
GO

Sequence cautioni

The sequence AAF99786.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012463 Genomic DNA. Translation: AAF99786.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE32221.1.
BT030472 mRNA. Translation: ABP88126.1.
RefSeqiNP_175220.2. NM_103682.3.
UniGeneiAt.38526.

Genome annotation databases

EnsemblPlantsiAT1G47840.1; AT1G47840.1; AT1G47840.
GeneIDi841200.
KEGGiath:AT1G47840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012463 Genomic DNA. Translation: AAF99786.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE32221.1 .
BT030472 mRNA. Translation: ABP88126.1 .
RefSeqi NP_175220.2. NM_103682.3.
UniGenei At.38526.

3D structure databases

ProteinModelPortali Q9FZG4.
SMRi Q9FZG4. Positions 30-488.
ModBasei Search...

Proteomic databases

PaxDbi Q9FZG4.
PRIDEi Q9FZG4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G47840.1 ; AT1G47840.1 ; AT1G47840 .
GeneIDi 841200.
KEGGi ath:AT1G47840.

Organism-specific databases

TAIRi AT1G47840.

Phylogenomic databases

eggNOGi COG5026.
HOGENOMi HOG000162670.
InParanoidi Q9FZG4.
KOi K00844.
OMAi QKDCATP.
PhylomeDBi Q9FZG4.

Enzyme and pathway databases

BioCyci ARA:AT1G47840-MONOMER.

Gene expression databases

Genevestigatori Q9FZG4.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Arabidopsis ORF clones."
    Bautista-Mercan V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.

Entry informationi

Entry nameiHXKL1_ARATH
AccessioniPrimary (citable) accession number: Q9FZG4
Secondary accession number(s): A4VCN1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: June 11, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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