Q9FZ57 (TPS2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2
EC=2.4.1.15

Alternative name(s):
Trehalose-6-phosphate synthase 2
Short name=AtTPS2

Gene names

Name:	TPS2
Ordered Locus Names:	At1g16980
ORF Names:	F6I1.1

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	822 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
Sequence similarities	In the N-terminal section; belongs to the glycosyltransferase 20 family. In the C-terminal section; belongs to the trehalose phosphatase family.
Sequence caution	The sequence AEE29528.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 822	822	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2		PRO_0000324823
Regions
	Region	12 – 479	468	Glycosyltransferase

Sequences

	Sequence		Length	Mass (Da)
	Q9FZ57 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 6270EB4998DBD7D5	FASTA	822	93,005
	10 20 30 40 50 60 MMDYDDARGE RPRLLVVANR LPVSAKRTGE NSWSLEMSPG GLVSGLLGIT SQFDTKWVGW 70 80 90 100 110 120 PGVDVHDEIE KNALTESLAE MKCIPVFLNG VFDQYYNGYC NGILWPILHH MGLPQEDQHD 130 140 150 160 170 180 TNQTFETQYD AYKKANRMFL DVIIDNYEEG DIVWCHDYHL MFLPQYLKEY NNKIKVGWFL 190 200 210 220 230 240 HSPFPSSEVY KTLPSRSELL RAILAADLLG FHTYDFARHF LSTCTRILGV EGTHEGVVYQ 250 260 270 280 290 300 GRVTRVAVFP IGIDPDRFIR TCKLPEVTQQ MNELQEKFAG KKVILGVDRL DMIKGIPQKY 310 320 330 340 350 360 LAFEKFLEEN PYWRDKVVLV QIAVPTRNDV PEYRKLKSQV HGLVGRINGR FGSVSSLPIH 370 380 390 400 410 420 HLDCSVDFNY LCAIYAIADV MLVTSLRDGM NLVSYEFVAC QEAKKGVLVL SEFAGAGQSL 430 440 450 460 470 480 GVGALIVNPW DVTEVSSAIK EALNMPAEER ETRHRSNFQY VCTHSAEKWG LDFMSELNGI 490 500 510 520 530 540 IPESEMQMRK IPLQLPEQDV IQQYSQSNNR LIILGFFGTL AEPMNSGTKE MDLKLNPELK 550 560 570 580 590 600 GTLKALCNDP KTTVVVLSRS GKNILNKNFG ESNIWLAAEN GMFEKQTTGE WVTNMPQNVN 610 620 630 640 650 660 LDWVDGVKNV FKYFTDRTPR SYFEASETSL VWNYEYADVE FGRAQARDLL QYLWAGPISN 670 680 690 700 710 720 ASVDVVRGNH SVEVHAIGET KGAAIGRILG EIVHRKSMTT PIDFVFCSGY FLEKDEDIYT 730 740 750 760 770 780 FFESKILSSK SPNGLDLKKE NYFSAAIGQA RTKARYVIDS AHGVVDLLHK LAVVADTTMT 790 800 810 820 DSFSDSEIYE PRDANANENS KRWINSVRRR KVEIGDTGQI GM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana." Leyman B., Van Dijck P., Thevelein J.M. Trends Plant Sci. 6:510-513(2001) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC051629 Genomic DNA. Translation: AAF99834.1. CP002684 Genomic DNA. Translation: AEE29528.1. Different initiation.
IPI	IPI00527121. IPI01019880.
PIR	E86305.
RefSeq	NP_173142.1. NM_101559.1.
UniGene	At.41859.
3D structure databases
HSSP	HSSP built from PDB template 1GZ5 based on UniProtKB P31677.
ProteinModelPortal	Q9FZ57.
SMR	Q9FZ57. Positions 13-482.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G16980.1-P.
Protein family/group databases
CAZy	GT20. Glycosyltransferase Family 20.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	838269.
KEGG	ath:AT1G16980.
Organism-specific databases
TAIR	At1g16980.
Phylogenomic databases
eggNOG	COG0380.
HOGENOM	HOG000191477.
InParanoid	Q9FZ57.
KO	K16055.
PhylomeDB	Q9FZ57.
Gene expression databases
ArrayExpress	Q9FZ57.
Genevestigator	Q9FZ57.
Family and domain databases
Gene3D	3.40.50.1000. 2 hits.
InterPro	IPR001830. Glyco_trans_20. IPR023214. HAD-like_dom. IPR012766. Trehalose_OtsA. IPR003337. Trehalose_PPase. [Graphical view]
Pfam	PF00982. Glyco_transf_20. 1 hit. PF02358. Trehalose_PPase. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR02400. trehalose_OtsA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TPS2_ARATH

Accession

Primary (citable) accession number: Q9FZ57
Secondary accession number(s): F4I627

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program