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Q9FZ29 (MAN1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannan endo-1,4-beta-mannosidase 1

EC=3.2.1.78
Alternative name(s):
Beta-mannanase 1
Endo-beta-1,4-mannanase 1
Short name=AtMAN1
Gene names
Name:MAN1
Ordered Locus Names:At1g02310
ORF Names:T6A9.1
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

Subcellular location

Secreted Potential.

Tissue specificity

Expressed in roots, stems and flowers. Ref.4

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmannan endo-1,4-beta-mannosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 411394Mannan endo-1,4-beta-mannosidase 1
PRO_0000277474

Sites

Active site1981Proton donor By similarity
Active site3191Nucleophile By similarity

Amino acid modifications

Glycosylation331N-linked (GlcNAc...) Potential
Glycosylation2021N-linked (GlcNAc...) Potential
Glycosylation3661N-linked (GlcNAc...) Potential
Glycosylation3841N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9FZ29 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: B72ECB54C4D7F218

FASTA41146,290
        10         20         30         40         50         60 
MLNILPFFLF FLPFLIGNNR ICVAVKTGFV GRNGTQFVLN GEQVYLNGFN AYWMMTTAAD 

        70         80         90        100        110        120 
TASKGRATVT TALRQASAVG MNVARIWGFN EGDYIPLQIS PGSYSEDVFK GLDFVVYEAG 

       130        140        150        160        170        180 
RFNIKLIISL VNNFEDYGGR KKYVEWAGLD EPDEFYTNSA VKQFYKNHVK TVLTRKNTIT 

       190        200        210        220        230        240 
GRMYKDDPTI FSWELINEPR CNDSTASNIL QDWVKEMASY VKSIDSNHLL EIGLEGFYGE 

       250        260        270        280        290        300 
SIPERTVYNP GGRVLTGTDF ITNNQIPDID FATIHIYPDS WLPLQSSRTG EQDTFVDRWI 

       310        320        330        340        350        360 
GAHIEDCDNI IKKPLLITEF GKSSKYPGFS LEKRNKFFQR VYDVIYDSAR AGGSCTGGVF 

       370        380        390        400        410 
WQLTTNRTGL LGDGYEVFMQ AGPNTTAQLI ADQSSKLKNL KYPPLVTHSA E 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"The endo-beta-mannanase gene families in Arabidopsis, rice, and poplar."
Yuan J.S., Yang X., Lai J., Lin H., Cheng Z.-M., Nonogaki H., Chen F.
Funct. Integr. Genomics 7:1-16(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, TISSUE SPECIFICITY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC064879 Genomic DNA. Translation: AAG00883.1.
CP002684 Genomic DNA. Translation: AEE27414.1.
AY081352 mRNA. Translation: AAL91241.1.
BT002154 mRNA. Translation: AAN72165.1.
PIRD86153.
RefSeqNP_171733.2. NM_100112.3.
UniGeneAt.23486.
At.42610.

3D structure databases

ProteinModelPortalQ9FZ29.
SMRQ9FZ29. Positions 29-400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G02310.1-P.

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.

Proteomic databases

PaxDbQ9FZ29.
PRIDEQ9FZ29.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G02310.1; AT1G02310.1; AT1G02310.
GeneID839444.
KEGGath:AT1G02310.

Organism-specific databases

TAIRAT1G02310.

Phylogenomic databases

eggNOGCOG3934.
HOGENOMHOG000169952.
InParanoidQ9FZ29.
OMAFATIHIY.
PhylomeDBQ9FZ29.

Enzyme and pathway databases

BioCycARA:AT1G02310-MONOMER.

Gene expression databases

GenevestigatorQ9FZ29.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMAN1_ARATH
AccessionPrimary (citable) accession number: Q9FZ29
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names