Q9FZ24 (PPR4_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pentatricopeptide repeat-containing protein At1g02370, mitochondrial

Gene names

Ordered Locus Names:	At1g02370
ORF Names:	T6A9.6

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	537 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Mitochondrion Potential.
Sequence similarities	Belongs to the PPR family. P subfamily. Contains 7 PPR (pentatricopeptide) repeats.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Repeat Transit peptide
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 18	18	Mitochondrion Potential
	Chain	19 – 537	519	Pentatricopeptide repeat-containing protein At1g02370, mitochondrial		PRO_0000342745
Regions
	Repeat	171 – 205	35	PPR 1
	Repeat	206 – 240	35	PPR 2
	Repeat	241 – 275	35	PPR 3
	Repeat	277 – 307	31	PPR 4
	Repeat	312 – 346	35	PPR 5
	Repeat	347 – 377	31	PPR 6
	Repeat	382 – 416	35	PPR 7
Experimental info
	Sequence conflict	233	1	M → I in AAL38889. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q9FZ24 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: DE27DB5C3566D789	FASTA	537	60,353
	10 20 30 40 50 60 MNFRNLIASG SRLGKRFCAT VFAPASATGI VEASVSSPAA ANVVEASVSS PAAENGVRTS 70 80 90 100 110 120 VAAPTVASRQ RELYKKLSML SVTGGTVAET LNQFIMEGIT VRKDDLFRCA KTLRKFRRPQ 130 140 150 160 170 180 HAFEIFDWME KRKMTFSVSD HAICLDLIGK TKGLEAAENY FNNLDPSAKN HQSTYGALMN 190 200 210 220 230 240 CYCVELEEEK AKAHFEIMDE LNFVNNSLPF NNMMSMYMRL SQPEKVPVLV DAMKQRGISP 250 260 270 280 290 300 CGVTYSIWMQ SCGSLNDLDG LEKIIDEMGK DSEAKTTWNT FSNLAAIYTK AGLYEKADSA 310 320 330 340 350 360 LKSMEEKMNP NNRDSHHFLM SLYAGISKGP EVYRVWESLK KARPEVNNLS YLVMLQAMSK 370 380 390 400 410 420 LGDLDGIKKI FTEWESKCWA YDMRLANIAI NTYLKGNMYE EAEKILDGAM KKSKGPFSKA 430 440 450 460 470 480 RQLLMIHLLE NDKADLAMKH LEAAVSDSAE NKDEWGWSSE LVSLFFLHFE KAKDVDGAED 490 500 510 520 530 FCKILSNWKP LDSETMTFLI KTYAAAEKTS PDMRERLSQQ QIEVSEEIQD LLKTVCP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis." Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C., Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M., Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B., Taconnat L., Small I. Plant Cell 16:2089-2103(2004) [PubMed: 15269332] [Abstract] Cited for: GENE FAMILY.
+	Additional computationally mapped references.

Web resources

Arabidopsis PPR Protein Database

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC064879 Genomic DNA. Translation: AAG00888.1. CP002684 Genomic DNA. Translation: AEE27421.1. AY065448 mRNA. Translation: AAL38889.1.
IPI	IPI00536138.
PIR	A86154.
RefSeq	NP_171739.1. NM_100118.4.
UniGene	At.28478.
3D structure databases
ProteinModelPortal	Q9FZ24.
ModBase	Search...
Proteomic databases
PRIDE	Q9FZ24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G02370.1; AT1G02370.1; AT1G02370.
GeneID	837735.
GenomeReviews	Gene locus AT1G02370 in contig CT485782_GR.
KEGG	ath:AT1G02370.
NMPDR	fig|3702.1.peg.356.
Organism-specific databases
GeneFarm	4842. 436.
TAIR	At1g02370.
Phylogenomic databases
eggNOG	KOG4197.
GeneTree	EPGT00050000001046.
HOGENOM	HBG320341.
InParanoid	Q9FZ24.
OMA	FLMSLYA.
PhylomeDB	Q9FZ24.
ProtClustDB	CLSN2714603.
Gene expression databases
Genevestigator	Q9FZ24.
Family and domain databases
InterPro	IPR002885. Pentatricopeptide_repeat. IPR011990. TPR-like_helical. [Graphical view]
Gene3D	G3DSA:1.25.40.10. TPR-like_helical. 2 hits.
Pfam	PF01535. PPR. 4 hits. [Graphical view]
PROSITE	PS51375. PPR. 7 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPR4_ARATH

Accession

Primary (citable) accession number: Q9FZ24
Secondary accession number(s): Q8VYY9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program