Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

BEL1-like homeodomain protein 10

Gene

BLH10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi351 – 41363HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
BEL1-like homeodomain protein 10
Short name:
BEL1-like protein 10
Gene namesi
Name:BLH10
Synonyms:BLH5
Ordered Locus Names:At1g19700
ORF Names:F14P1.20, F6F9.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G19700.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 538538BEL1-like homeodomain protein 10PRO_0000315466Add
BLAST

Proteomic databases

PaxDbiQ9FXG8.
PRIDEiQ9FXG8.

PTM databases

iPTMnetiQ9FXG8.

Expressioni

Gene expression databases

GenevisibleiQ9FXG8. AT.

Interactioni

Subunit structurei

Interacts with TLP1. May form heterodimeric complexes with TALE/KNOX proteins (By similarity). Interacts with OFP1, OFP2, OFP4 and OFP5.By similarity2 Publications

Protein-protein interaction databases

BioGridi23797. 14 interactions.
IntActiQ9FXG8. 15 interactions.
STRINGi3702.AT1G19700.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FXG8.
SMRiQ9FXG8. Positions 359-413.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni169 – 18517SR/KY domainAdd
BLAST
Regioni231 – 30272BELL domainAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi448 – 4536Poly-Gln
Compositional biasi455 – 4606Poly-Asn
Compositional biasi490 – 4934Poly-Gln

Domaini

The SR/KY and BELL domains are responsive for the interaction between the TALE/BELL proteins and the TALE/KNOX proteins.

Sequence similaritiesi

Belongs to the TALE/BELL homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
InParanoidiQ9FXG8.
OMAiEPNSTNQ.
PhylomeDBiQ9FXG8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR006563. POX_dom.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF07526. POX. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM00574. POX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9FXG8-1) [UniParc]FASTAAdd to basket

Also known as: BLH10B

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAVYYTSNVG CYQQEPIFLN HQQQNQQASS SSAAASFTVT GGDTVRNEMV
60 70 80 90 100
FIPPTTTGDV VTGNGTVSSS DLSFHDGQGL SLSLGTQISV APFHFHQYQL
110 120 130 140 150
GFTSQNPSIS VKETSPFHVD EMSVKSKEMI LLGQSDPSSG YAGNGGNGFY
160 170 180 190 200
NNYRYNETSG GFMSSVLRSR YLKPAQNLLD EVVSVKKELN QMGKKKMKVN
210 220 230 240 250
DFNSGSKEIE GGGGELSSDS NGKSIELSTI EREELQNKKN KLLTMVDEVD
260 270 280 290 300
KRYNQYYHQM EALASSFEIV AGLGSAKPYT SVALNRISRH FRALRDAIKE
310 320 330 340 350
QIQIVREKLG EKGGESLDEQ QGERIPRLRY LDQRLRQQRA LHQQLGMVRP
360 370 380 390 400
AWRPQRGLPE NSVSVLRAWL FEHFLHPYPK ESEKIMLAKQ TGLSKNQVAN
410 420 430 440 450
WFINARVRLW KPMIEEMYKE EFGDESELLI SKSSQEPNST NQEDSSSQQQ
460 470 480 490 500
QQQENNNNSN LAYSSADTTN IVFSSETKPD RVLGNDNDPQ QQQINRSSDY
510 520 530
DTLMNYHGFG VDDYRYISGS NQQESRFSNS HHLHDFVV
Length:538
Mass (Da):60,636
Last modified:March 1, 2001 - v1
Checksum:i444FE541B7FF6803
GO
Isoform 2 (identifier: Q9FXG8-2) [UniParc]FASTAAdd to basket

Also known as: BLH10A

The sequence of this isoform differs from the canonical sequence as follows:
     249-267: VDKRYNQYYHQMEALASSF → NLSPFSCSSRRNKGTNSDC
     268-538: Missing.

Note: May be due to a competing acceptor splice site. No experimental confirmation available.
Show »
Length:267
Mass (Da):28,999
Checksum:iCF6B9D0C641D071C
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti193 – 1931G → S in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0. 1 Publication
Natural varianti204 – 2041S → N in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0. 1 Publication
Natural varianti213 – 2131G → GS in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0.
Natural varianti218 – 2181S → N in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0. 1 Publication
Natural varianti233 – 2331E → D in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0. 1 Publication
Natural varianti236 – 2361Q → H in strain: cv. Ag-0, cv. Bs-1, cv. Chi-1, cv. Cvi-0, cv. Kas-1, cv. Ita-0, cv. Landsberg erecta, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0. 1 Publication
Natural varianti289 – 2891R → C in strain: cv. Ag-0, cv. Lisse. 1 Publication

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei249 – 26719VDKRY…LASSF → NLSPFSCSSRRNKGTNSDC in isoform 2. 1 PublicationVSP_030557Add
BLAST
Alternative sequencei268 – 538271Missing in isoform 2. 1 PublicationVSP_030558Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY570508 mRNA. Translation: AAS78200.1.
AC007797 Genomic DNA. Translation: AAG12557.1.
AC024609 Genomic DNA. No translation available.
CP002684 Genomic DNA. Translation: AEE29884.1.
CP002684 Genomic DNA. Translation: AEE29885.1.
CP002684 Genomic DNA. Translation: AEE29886.1.
AY052366 mRNA. Translation: AAK96557.1.
AY059666 mRNA. Translation: AAL31159.1.
DQ132268 Genomic DNA. Translation: AAZ73632.1.
DQ132269 Genomic DNA. Translation: AAZ73633.1.
DQ132270 Genomic DNA. Translation: AAZ73634.1.
DQ132271 Genomic DNA. Translation: AAZ73635.1.
DQ132272 Genomic DNA. Translation: AAZ73636.1.
DQ132273 Genomic DNA. Translation: AAZ73637.1.
DQ132274 Genomic DNA. Translation: AAZ73638.1.
DQ132275 Genomic DNA. Translation: AAZ73639.1.
DQ132276 Genomic DNA. Translation: AAZ73640.1.
DQ132277 Genomic DNA. Translation: AAZ73641.1.
DQ132278 Genomic DNA. Translation: AAZ73642.1.
DQ132279 Genomic DNA. Translation: AAZ73643.1.
DQ132280 Genomic DNA. Translation: AAZ73644.1.
DQ132281 Genomic DNA. Translation: AAZ73645.1.
DQ132282 Genomic DNA. Translation: AAZ73646.1.
DQ132283 Genomic DNA. Translation: AAZ73647.1.
DQ132284 Genomic DNA. Translation: AAZ73648.1.
DQ132285 Genomic DNA. Translation: AAZ73649.1.
DQ132286 Genomic DNA. Translation: AAZ73650.1.
PIRiH86329.
RefSeqiNP_001154352.1. NM_001160880.1. [Q9FXG8-1]
NP_001185040.1. NM_001198111.1. [Q9FXG8-1]
NP_173400.1. NM_101826.2. [Q9FXG8-1]
UniGeneiAt.26495.

Genome annotation databases

EnsemblPlantsiAT1G19700.1; AT1G19700.1; AT1G19700. [Q9FXG8-1]
AT1G19700.2; AT1G19700.2; AT1G19700. [Q9FXG8-1]
AT1G19700.3; AT1G19700.3; AT1G19700. [Q9FXG8-1]
GeneIDi838558.
KEGGiath:AT1G19700.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY570508 mRNA. Translation: AAS78200.1.
AC007797 Genomic DNA. Translation: AAG12557.1.
AC024609 Genomic DNA. No translation available.
CP002684 Genomic DNA. Translation: AEE29884.1.
CP002684 Genomic DNA. Translation: AEE29885.1.
CP002684 Genomic DNA. Translation: AEE29886.1.
AY052366 mRNA. Translation: AAK96557.1.
AY059666 mRNA. Translation: AAL31159.1.
DQ132268 Genomic DNA. Translation: AAZ73632.1.
DQ132269 Genomic DNA. Translation: AAZ73633.1.
DQ132270 Genomic DNA. Translation: AAZ73634.1.
DQ132271 Genomic DNA. Translation: AAZ73635.1.
DQ132272 Genomic DNA. Translation: AAZ73636.1.
DQ132273 Genomic DNA. Translation: AAZ73637.1.
DQ132274 Genomic DNA. Translation: AAZ73638.1.
DQ132275 Genomic DNA. Translation: AAZ73639.1.
DQ132276 Genomic DNA. Translation: AAZ73640.1.
DQ132277 Genomic DNA. Translation: AAZ73641.1.
DQ132278 Genomic DNA. Translation: AAZ73642.1.
DQ132279 Genomic DNA. Translation: AAZ73643.1.
DQ132280 Genomic DNA. Translation: AAZ73644.1.
DQ132281 Genomic DNA. Translation: AAZ73645.1.
DQ132282 Genomic DNA. Translation: AAZ73646.1.
DQ132283 Genomic DNA. Translation: AAZ73647.1.
DQ132284 Genomic DNA. Translation: AAZ73648.1.
DQ132285 Genomic DNA. Translation: AAZ73649.1.
DQ132286 Genomic DNA. Translation: AAZ73650.1.
PIRiH86329.
RefSeqiNP_001154352.1. NM_001160880.1. [Q9FXG8-1]
NP_001185040.1. NM_001198111.1. [Q9FXG8-1]
NP_173400.1. NM_101826.2. [Q9FXG8-1]
UniGeneiAt.26495.

3D structure databases

ProteinModelPortaliQ9FXG8.
SMRiQ9FXG8. Positions 359-413.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi23797. 14 interactions.
IntActiQ9FXG8. 15 interactions.
STRINGi3702.AT1G19700.1.

PTM databases

iPTMnetiQ9FXG8.

Proteomic databases

PaxDbiQ9FXG8.
PRIDEiQ9FXG8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G19700.1; AT1G19700.1; AT1G19700. [Q9FXG8-1]
AT1G19700.2; AT1G19700.2; AT1G19700. [Q9FXG8-1]
AT1G19700.3; AT1G19700.3; AT1G19700. [Q9FXG8-1]
GeneIDi838558.
KEGGiath:AT1G19700.

Organism-specific databases

TAIRiAT1G19700.

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
InParanoidiQ9FXG8.
OMAiEPNSTNQ.
PhylomeDBiQ9FXG8.

Miscellaneous databases

PROiQ9FXG8.

Gene expression databases

GenevisibleiQ9FXG8. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR006563. POX_dom.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF07526. POX. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM00574. POX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The BELL family of homeodomain proteins in Arabidopsis."
    Milich R., Putterill J.J.
    Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: cv. Columbia.
  5. "High-diversity genes in the Arabidopsis genome."
    Cork J.M., Purugganan M.D.
    Genetics 170:1897-1911(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 170-405 (ISOFORM 1), VARIANTS SER-193; ASN-204; GLY-213-214-SER; ASN-218; ASP-233; HIS-236 AND CYS-289.
    Strain: cv. Ag-0, cv. Bla-10, cv. Bs-1, cv. Chi-1, cv. Co-1, cv. Cvi-0, cv. Da(1)-12, cv. Gr-3, cv. Ita-0, cv. Kas-1, cv. Kr-0, cv. Landsberg erecta, cv. Lip-0, cv. Lisse, cv. Me-0, cv. Mt-0, cv. Oy-0, cv. Te-0 and cv. Tu-1.
  6. "Competence to respond to floral inductive signals requires the homeobox genes PENNYWISE and POUND-FOOLISH."
    Smith H.M.S., Campbell B.C.C., Hake S.
    Curr. Biol. 14:812-817(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY ORGANIZATION.
  7. "A central role of Arabidopsis thaliana ovate family proteins in networking and subcellular localization of 3-aa loop extension homeodomain proteins."
    Hackbusch J., Richter K., Muller J., Salamini F., Uhrig J.F.
    Proc. Natl. Acad. Sci. U.S.A. 102:4908-4912(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH OFP1; OFP2; OFP4 AND OFP5.
  8. "Blue light diminishes interaction of PAS/LOV proteins, putative blue light receptors in Arabidopsis thaliana, with their interacting partners."
    Ogura Y., Komatsu A., Zikihara K., Nanjo T., Tokutomi S., Wada M., Kiyosue T.
    J. Plant Res. 121:97-105(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH TLP1.

Entry informationi

Entry nameiBLH10_ARATH
AccessioniPrimary (citable) accession number: Q9FXG8
Secondary accession number(s): Q3YIF0
, Q3YIF5, Q3YIG1, Q3YIG2, Q3YIG4, Q3YIG6, Q940X8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2001
Last modified: February 17, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.