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Q9FXE5

- FUCO3_ARATH

UniProt

Q9FXE5 - FUCO3_ARATH

Protein

Alpha-L-fucosidase 3

Gene

FXG1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Hydrolyzes alpha-1,2-linked fucose. Also active on fucosylated xyloglucan oligosaccharides.1 Publication

    Catalytic activityi

    An alpha-L-fucoside + H2O = L-fucose + an alcohol.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei37 – 371NucleophileBy similarity
    Active sitei345 – 3451By similarity
    Active sitei348 – 3481By similarity

    GO - Molecular functioni

    1. alpha-L-fucosidase activity Source: TAIR
    2. hydrolase activity, acting on ester bonds Source: InterPro

    GO - Biological processi

    1. lipid metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciARA:AT1G67830-MONOMER.
    MetaCyc:AT1G67830-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alpha-L-fucosidase 3 (EC:3.2.1.51)
    Alternative name(s):
    Alpha-1,2-fucosidase
    Short name:
    AtFXG1
    Alpha-L-fucoside fucohydrolase 3
    Gene namesi
    Name:FXG1
    Ordered Locus Names:At1g67830
    ORF Names:F12A21.4
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G67830.

    Subcellular locationi

    Secretedextracellular spaceapoplast 2 Publications

    GO - Cellular componenti

    1. apoplast Source: UniProtKB-SubCell
    2. plant-type cell wall Source: TAIR

    Keywords - Cellular componenti

    Apoplast, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 372349Alpha-L-fucosidase 3PRO_0000225694Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi96 – 961N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi114 – 1141N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi139 – 1391N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi182 – 1821N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ9FXE5.
    PRIDEiQ9FXE5.

    Expressioni

    Tissue specificityi

    High expression in younger leaves and in the apical region of the inflorescence stem.1 Publication

    Gene expression databases

    GenevestigatoriQ9FXE5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FXE5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'GDSL' lipolytic enzyme family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG245146.
    HOGENOMiHOG000237648.
    InParanoidiQ9FXE5.
    KOiK01206.
    OMAiKRRRCQA.
    PhylomeDBiQ9FXE5.

    Family and domain databases

    Gene3Di3.40.50.1110. 1 hit.
    InterProiIPR001087. Lipase_GDSL.
    IPR013831. SGNH_hydro-type_esterase_dom.
    [Graphical view]
    PfamiPF00657. Lipase_GDSL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9FXE5-1 [UniParc]FASTAAdd to Basket

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    MNPILSSLFA LSLLSSLSPS THAHQCHFPA IFNFGDSNSD TGGLSAAFGQ    50
    AGPPHGSSFF GSPAGRYCDG RLVIDFIAES LGLPYLSAFL DSVGSNFSHG 100
    ANFATAGSPI RALNSTLRQS GFSPFSLDVQ FVQFYNFHNR SQTVRSRGGV 150
    YKTMLPESDS FSKALYTFDI GQNDLTAGYF ANKTVEQVET EVPEIISQFM 200
    NAIKNIYGQG GRYFWIHNTG PIGCLAYVIE RFPNKASDFD SHGCVSPLNH 250
    LAQQFNHALK QAVIELRSSL SEAAITYVDV YSLKHELFVH AQGHGFKGSL 300
    VSCCGHGGKY NYNKGIGCGM KKIVKGKEVY IGKPCDEPDK AVVWDGVHFT 350
    QAANKFIFDK IAPGLSKACK RQ 372
    Length:372
    Mass (Da):40,462
    Last modified:March 1, 2001 - v1
    Checksum:iD88CA3FEE74A8155
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti11 – 111L → R in BAD43265. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008113 Genomic DNA. Translation: AAG28886.1.
    CP002684 Genomic DNA. Translation: AEE34703.1.
    AK175502 mRNA. Translation: BAD43265.1.
    RefSeqiNP_176949.1. NM_105451.3.
    UniGeneiAt.23529.
    At.35596.

    Genome annotation databases

    EnsemblPlantsiAT1G67830.1; AT1G67830.1; AT1G67830.
    GeneIDi843109.
    KEGGiath:AT1G67830.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008113 Genomic DNA. Translation: AAG28886.1 .
    CP002684 Genomic DNA. Translation: AEE34703.1 .
    AK175502 mRNA. Translation: BAD43265.1 .
    RefSeqi NP_176949.1. NM_105451.3.
    UniGenei At.23529.
    At.35596.

    3D structure databases

    ProteinModelPortali Q9FXE5.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9FXE5.
    PRIDEi Q9FXE5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G67830.1 ; AT1G67830.1 ; AT1G67830 .
    GeneIDi 843109.
    KEGGi ath:AT1G67830.

    Organism-specific databases

    TAIRi AT1G67830.

    Phylogenomic databases

    eggNOGi NOG245146.
    HOGENOMi HOG000237648.
    InParanoidi Q9FXE5.
    KOi K01206.
    OMAi KRRRCQA.
    PhylomeDBi Q9FXE5.

    Enzyme and pathway databases

    BioCyci ARA:AT1G67830-MONOMER.
    MetaCyc:AT1G67830-MONOMER.

    Gene expression databases

    Genevestigatori Q9FXE5.

    Family and domain databases

    Gene3Di 3.40.50.1110. 1 hit.
    InterProi IPR001087. Lipase_GDSL.
    IPR013831. SGNH_hydro-type_esterase_dom.
    [Graphical view ]
    Pfami PF00657. Lipase_GDSL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
      Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
      , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
      Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-372.
      Strain: cv. Columbia.
    4. "AtFXG1, an Arabidopsis gene encoding alpha-L-fucosidase active against fucosylated xyloglucan oligosaccharides."
      de La Torre F., Sampedro J., Zarra I., Revilla G.
      Plant Physiol. 128:247-255(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.
    5. "Apoplastic glycosidases active against xyloglucan oligosaccharides of Arabidopsis thaliana."
      Iglesias N., Abelenda J.A., Rodino M., Sampedro J., Revilla G., Zarra I.
      Plant Cell Physiol. 47:55-63(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiFUCO3_ARATH
    AccessioniPrimary (citable) accession number: Q9FXE5
    Secondary accession number(s): Q681W5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 7, 2006
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Caution

    The functional assignment is controversial.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3