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Protein

Probable protein phosphatase 2C 14

Gene

At1g67820

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi156 – 1561Manganese 1By similarity
Metal bindingi156 – 1561Manganese 2By similarity
Metal bindingi157 – 1571Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi318 – 3181Manganese 2By similarity
Metal bindingi431 – 4311Manganese 2By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G67820-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 14 (EC:3.1.3.16)
Short name:
AtPP2C14
Alternative name(s):
Protein phosphatase AP2C4
Gene namesi
Ordered Locus Names:At1g67820
ORF Names:F12A21.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G67820.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Probable protein phosphatase 2C 14PRO_0000367945Add
BLAST

Proteomic databases

PaxDbiQ9FXE4.
PRIDEiQ9FXE4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9FXE4. baseline and differential.

Interactioni

Protein-protein interaction databases

BioGridi28329. 2 interactions.
STRINGi3702.AT1G67820.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4. Positions 121-440.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini120 – 440321PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
PhylomeDBiQ9FXE4.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FXE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNKLRSEET ITSLSSFMAS TLSIASPSPC SIPLSVTKVS PLKRKRPTHL
60 70 80 90 100
NIPDLNPQQP ISTDYFRFRE GDAKVSPLKR KRPAHLNIPD LNPQQPIRTD
110 120 130 140 150
YFSFTDFAHQ NGTVSFGGNG FGVVSRNGKK KFMEDTHRIV PCLVGNSKKS
160 170 180 190 200
FFGVYDGHGG AKAAEFVAEN LHKYVVEMME NCKGKEEKVE AFKAAFLRTD
210 220 230 240 250
RDFLEKGVVS GACCVTAVIQ DQEMIVSNLG DCRAVLCRAG VAEALTDDHK
260 270 280 290 300
PGRDDEKERI ESQGGYVDNH QGAWRVQGIL AVSRSIGDAH LKKWVVAEPE
310 320 330 340 350
TRVLELEQDM EFLVLASDGL WDVVSNQEAV YTVLHVLAQR KTPKESEEEN
360 370 380 390 400
LVQGFVNMSP SSKLRRASLV KSPRCAKSQS YYYNSENESP SLNREIGSSP
410 420 430 440
SKSPITPWKS LWAKAACKEL ANLAAKRGSM DDITVVIIDL NHYKG
Length:445
Mass (Da):49,353
Last modified:April 14, 2009 - v2
Checksum:iC0E01A328F2F4CFF
GO

Sequence cautioni

The sequence AAG28911.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence BX813565 differs from that shown.Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.3.
UniGeneiAt.23529.
At.35596.

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
KEGGiath:AT1G67820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.3.
UniGeneiAt.23529.
At.35596.

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4. Positions 121-440.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi28329. 2 interactions.
STRINGi3702.AT1G67820.1.

Proteomic databases

PaxDbiQ9FXE4.
PRIDEiQ9FXE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
KEGGiath:AT1G67820.

Organism-specific databases

TAIRiAT1G67820.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
PhylomeDBiQ9FXE4.

Enzyme and pathway databases

BioCyciARA:AT1G67820-MONOMER.

Miscellaneous databases

PROiQ9FXE4.

Gene expression databases

ExpressionAtlasiQ9FXE4. baseline and differential.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
    Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
    Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C14_ARATH
AccessioniPrimary (citable) accession number: Q9FXE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: July 22, 2015
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.