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Q9FXE4

- P2C14_ARATH

UniProt

Q9FXE4 - P2C14_ARATH

Protein

Probable protein phosphatase 2C 14

Gene

At1g67820

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 2 (14 Apr 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi156 – 1561Manganese 1By similarity
    Metal bindingi156 – 1561Manganese 2By similarity
    Metal bindingi157 – 1571Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi318 – 3181Manganese 2By similarity
    Metal bindingi431 – 4311Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G67820-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 14 (EC:3.1.3.16)
    Short name:
    AtPP2C14
    Alternative name(s):
    Protein phosphatase AP2C4
    Gene namesi
    Ordered Locus Names:At1g67820
    ORF Names:F12A21.5
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G67820.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 445445Probable protein phosphatase 2C 14PRO_0000367945Add
    BLAST

    Proteomic databases

    PaxDbiQ9FXE4.
    PRIDEiQ9FXE4.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9FXE4.
    GenevestigatoriQ9FXE4.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT1G67820.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FXE4.
    SMRiQ9FXE4. Positions 121-440.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini119 – 330212PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000090868.
    InParanoidiQ9FXE4.
    OMAiDMEFLVL.
    PhylomeDBiQ9FXE4.

    Family and domain databases

    Gene3Di3.60.40.10. 2 hits.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 2 hits.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9FXE4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNKLRSEET ITSLSSFMAS TLSIASPSPC SIPLSVTKVS PLKRKRPTHL    50
    NIPDLNPQQP ISTDYFRFRE GDAKVSPLKR KRPAHLNIPD LNPQQPIRTD 100
    YFSFTDFAHQ NGTVSFGGNG FGVVSRNGKK KFMEDTHRIV PCLVGNSKKS 150
    FFGVYDGHGG AKAAEFVAEN LHKYVVEMME NCKGKEEKVE AFKAAFLRTD 200
    RDFLEKGVVS GACCVTAVIQ DQEMIVSNLG DCRAVLCRAG VAEALTDDHK 250
    PGRDDEKERI ESQGGYVDNH QGAWRVQGIL AVSRSIGDAH LKKWVVAEPE 300
    TRVLELEQDM EFLVLASDGL WDVVSNQEAV YTVLHVLAQR KTPKESEEEN 350
    LVQGFVNMSP SSKLRRASLV KSPRCAKSQS YYYNSENESP SLNREIGSSP 400
    SKSPITPWKS LWAKAACKEL ANLAAKRGSM DDITVVIIDL NHYKG 445
    Length:445
    Mass (Da):49,353
    Last modified:April 14, 2009 - v2
    Checksum:iC0E01A328F2F4CFF
    GO

    Sequence cautioni

    The sequence BX813565 differs from that shown. Reason: Sequencing errors.
    The sequence AAG28911.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
    CP002684 Genomic DNA. Translation: AEE34702.1.
    BX813565 mRNA. No translation available.
    PIRiH96700.
    RefSeqiNP_176948.2. NM_105450.3.
    UniGeneiAt.23529.
    At.35596.

    Genome annotation databases

    EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
    GeneIDi843108.
    KEGGiath:AT1G67820.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008113 Genomic DNA. Translation: AAG28911.1 . Sequence problems.
    CP002684 Genomic DNA. Translation: AEE34702.1 .
    BX813565 mRNA. No translation available.
    PIRi H96700.
    RefSeqi NP_176948.2. NM_105450.3.
    UniGenei At.23529.
    At.35596.

    3D structure databases

    ProteinModelPortali Q9FXE4.
    SMRi Q9FXE4. Positions 121-440.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT1G67820.1-P.

    Proteomic databases

    PaxDbi Q9FXE4.
    PRIDEi Q9FXE4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G67820.1 ; AT1G67820.1 ; AT1G67820 .
    GeneIDi 843108.
    KEGGi ath:AT1G67820.

    Organism-specific databases

    TAIRi AT1G67820.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000090868.
    InParanoidi Q9FXE4.
    OMAi DMEFLVL.
    PhylomeDBi Q9FXE4.

    Enzyme and pathway databases

    BioCyci ARA:AT1G67820-MONOMER.

    Gene expression databases

    ArrayExpressi Q9FXE4.
    Genevestigatori Q9FXE4.

    Family and domain databases

    Gene3Di 3.60.40.10. 2 hits.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 2 hits.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
      Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
      Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C14_ARATH
    AccessioniPrimary (citable) accession number: Q9FXE4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 14, 2009
    Last modified: October 1, 2014
    This is version 85 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3