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Protein

Probable protein phosphatase 2C 14

Gene

At1g67820

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi156Manganese 1By similarity1
Metal bindingi156Manganese 2By similarity1
Metal bindingi157Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi318Manganese 2By similarity1
Metal bindingi431Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 14 (EC:3.1.3.16)
Short name:
AtPP2C14
Alternative name(s):
Protein phosphatase AP2C4
Gene namesi
Ordered Locus Names:At1g67820
ORF Names:F12A21.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G67820.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679451 – 445Probable protein phosphatase 2C 14Add BLAST445

Proteomic databases

PaxDbiQ9FXE4.

PTM databases

iPTMnetiQ9FXE4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9FXE4. baseline and differential.
GenevisibleiQ9FXE4. AT.

Interactioni

Protein-protein interaction databases

BioGridi28329. 2 interactors.
STRINGi3702.AT1G67820.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 440PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST321

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
OrthoDBiEOG09360JAN.
PhylomeDBiQ9FXE4.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FXE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNKLRSEET ITSLSSFMAS TLSIASPSPC SIPLSVTKVS PLKRKRPTHL
60 70 80 90 100
NIPDLNPQQP ISTDYFRFRE GDAKVSPLKR KRPAHLNIPD LNPQQPIRTD
110 120 130 140 150
YFSFTDFAHQ NGTVSFGGNG FGVVSRNGKK KFMEDTHRIV PCLVGNSKKS
160 170 180 190 200
FFGVYDGHGG AKAAEFVAEN LHKYVVEMME NCKGKEEKVE AFKAAFLRTD
210 220 230 240 250
RDFLEKGVVS GACCVTAVIQ DQEMIVSNLG DCRAVLCRAG VAEALTDDHK
260 270 280 290 300
PGRDDEKERI ESQGGYVDNH QGAWRVQGIL AVSRSIGDAH LKKWVVAEPE
310 320 330 340 350
TRVLELEQDM EFLVLASDGL WDVVSNQEAV YTVLHVLAQR KTPKESEEEN
360 370 380 390 400
LVQGFVNMSP SSKLRRASLV KSPRCAKSQS YYYNSENESP SLNREIGSSP
410 420 430 440
SKSPITPWKS LWAKAACKEL ANLAAKRGSM DDITVVIIDL NHYKG
Length:445
Mass (Da):49,353
Last modified:April 14, 2009 - v2
Checksum:iC0E01A328F2F4CFF
GO

Sequence cautioni

The sequence AAG28911 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BX813565 differs from that shown. Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.4.
UniGeneiAt.23529.
At.35596.

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
GrameneiAT1G67820.1; AT1G67820.1; AT1G67820.
KEGGiath:AT1G67820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.4.
UniGeneiAt.23529.
At.35596.

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi28329. 2 interactors.
STRINGi3702.AT1G67820.1.

PTM databases

iPTMnetiQ9FXE4.

Proteomic databases

PaxDbiQ9FXE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
GrameneiAT1G67820.1; AT1G67820.1; AT1G67820.
KEGGiath:AT1G67820.

Organism-specific databases

TAIRiAT1G67820.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
OrthoDBiEOG09360JAN.
PhylomeDBiQ9FXE4.

Miscellaneous databases

PROiQ9FXE4.

Gene expression databases

ExpressionAtlasiQ9FXE4. baseline and differential.
GenevisibleiQ9FXE4. AT.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C14_ARATH
AccessioniPrimary (citable) accession number: Q9FXE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: November 30, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.