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Q9FXE4

- P2C14_ARATH

UniProt

Q9FXE4 - P2C14_ARATH

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Protein

Probable protein phosphatase 2C 14

Gene

At1g67820

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi156 – 1561Manganese 1By similarity
Metal bindingi156 – 1561Manganese 2By similarity
Metal bindingi157 – 1571Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi318 – 3181Manganese 2By similarity
Metal bindingi431 – 4311Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G67820-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 14 (EC:3.1.3.16)
Short name:
AtPP2C14
Alternative name(s):
Protein phosphatase AP2C4
Gene namesi
Ordered Locus Names:At1g67820
ORF Names:F12A21.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G67820.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Probable protein phosphatase 2C 14PRO_0000367945Add
BLAST

Proteomic databases

PaxDbiQ9FXE4.
PRIDEiQ9FXE4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9FXE4. baseline and differential.
GenevestigatoriQ9FXE4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G67820.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4. Positions 121-440.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini119 – 330212PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
PhylomeDBiQ9FXE4.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FXE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNKLRSEET ITSLSSFMAS TLSIASPSPC SIPLSVTKVS PLKRKRPTHL
60 70 80 90 100
NIPDLNPQQP ISTDYFRFRE GDAKVSPLKR KRPAHLNIPD LNPQQPIRTD
110 120 130 140 150
YFSFTDFAHQ NGTVSFGGNG FGVVSRNGKK KFMEDTHRIV PCLVGNSKKS
160 170 180 190 200
FFGVYDGHGG AKAAEFVAEN LHKYVVEMME NCKGKEEKVE AFKAAFLRTD
210 220 230 240 250
RDFLEKGVVS GACCVTAVIQ DQEMIVSNLG DCRAVLCRAG VAEALTDDHK
260 270 280 290 300
PGRDDEKERI ESQGGYVDNH QGAWRVQGIL AVSRSIGDAH LKKWVVAEPE
310 320 330 340 350
TRVLELEQDM EFLVLASDGL WDVVSNQEAV YTVLHVLAQR KTPKESEEEN
360 370 380 390 400
LVQGFVNMSP SSKLRRASLV KSPRCAKSQS YYYNSENESP SLNREIGSSP
410 420 430 440
SKSPITPWKS LWAKAACKEL ANLAAKRGSM DDITVVIIDL NHYKG
Length:445
Mass (Da):49,353
Last modified:April 14, 2009 - v2
Checksum:iC0E01A328F2F4CFF
GO

Sequence cautioni

The sequence AAG28911.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence BX813565 differs from that shown. Reason: Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.3.
UniGeneiAt.23529.
At.35596.

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
KEGGiath:AT1G67820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1 .
BX813565 mRNA. No translation available.
PIRi H96700.
RefSeqi NP_176948.2. NM_105450.3.
UniGenei At.23529.
At.35596.

3D structure databases

ProteinModelPortali Q9FXE4.
SMRi Q9FXE4. Positions 121-440.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT1G67820.1-P.

Proteomic databases

PaxDbi Q9FXE4.
PRIDEi Q9FXE4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G67820.1 ; AT1G67820.1 ; AT1G67820 .
GeneIDi 843108.
KEGGi ath:AT1G67820.

Organism-specific databases

TAIRi AT1G67820.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000090868.
InParanoidi Q9FXE4.
OMAi DMEFLVL.
PhylomeDBi Q9FXE4.

Enzyme and pathway databases

BioCyci ARA:AT1G67820-MONOMER.

Gene expression databases

ExpressionAtlasi Q9FXE4. baseline and differential.
Genevestigatori Q9FXE4.

Family and domain databases

Gene3Di 3.60.40.10. 2 hits.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
    Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
    Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C14_ARATH
AccessioniPrimary (citable) accession number: Q9FXE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: November 26, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3