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Q9FXE4

- P2C14_ARATH

UniProt

Q9FXE4 - P2C14_ARATH

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Protein
Probable protein phosphatase 2C 14
Gene
At1g67820, F12A21.5
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi156 – 1561Manganese 1 By similarity
Metal bindingi156 – 1561Manganese 2 By similarity
Metal bindingi157 – 1571Manganese 1; via carbonyl oxygen By similarity
Metal bindingi318 – 3181Manganese 2 By similarity
Metal bindingi431 – 4311Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G67820-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 14 (EC:3.1.3.16)
Short name:
AtPP2C14
Alternative name(s):
Protein phosphatase AP2C4
Gene namesi
Ordered Locus Names:At1g67820
ORF Names:F12A21.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G67820.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Probable protein phosphatase 2C 14
PRO_0000367945Add
BLAST

Proteomic databases

PaxDbiQ9FXE4.
PRIDEiQ9FXE4.

Expressioni

Gene expression databases

ArrayExpressiQ9FXE4.
GenevestigatoriQ9FXE4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G67820.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9FXE4.
SMRiQ9FXE4. Positions 121-440.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini119 – 330212PP2C-like
Add
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000090868.
InParanoidiQ9FXE4.
OMAiDMEFLVL.
PhylomeDBiQ9FXE4.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FXE4-1 [UniParc]FASTAAdd to Basket

« Hide

MTNKLRSEET ITSLSSFMAS TLSIASPSPC SIPLSVTKVS PLKRKRPTHL    50
NIPDLNPQQP ISTDYFRFRE GDAKVSPLKR KRPAHLNIPD LNPQQPIRTD 100
YFSFTDFAHQ NGTVSFGGNG FGVVSRNGKK KFMEDTHRIV PCLVGNSKKS 150
FFGVYDGHGG AKAAEFVAEN LHKYVVEMME NCKGKEEKVE AFKAAFLRTD 200
RDFLEKGVVS GACCVTAVIQ DQEMIVSNLG DCRAVLCRAG VAEALTDDHK 250
PGRDDEKERI ESQGGYVDNH QGAWRVQGIL AVSRSIGDAH LKKWVVAEPE 300
TRVLELEQDM EFLVLASDGL WDVVSNQEAV YTVLHVLAQR KTPKESEEEN 350
LVQGFVNMSP SSKLRRASLV KSPRCAKSQS YYYNSENESP SLNREIGSSP 400
SKSPITPWKS LWAKAACKEL ANLAAKRGSM DDITVVIIDL NHYKG 445
Length:445
Mass (Da):49,353
Last modified:April 14, 2009 - v2
Checksum:iC0E01A328F2F4CFF
GO

Sequence cautioni

The sequence BX813565 differs from that shown. Reason: Sequencing errors.
The sequence AAG28911.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1.
BX813565 mRNA. No translation available.
PIRiH96700.
RefSeqiNP_176948.2. NM_105450.3.
UniGeneiAt.23529.
At.35596.

Genome annotation databases

EnsemblPlantsiAT1G67820.1; AT1G67820.1; AT1G67820.
GeneIDi843108.
KEGGiath:AT1G67820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC008113 Genomic DNA. Translation: AAG28911.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE34702.1 .
BX813565 mRNA. No translation available.
PIRi H96700.
RefSeqi NP_176948.2. NM_105450.3.
UniGenei At.23529.
At.35596.

3D structure databases

ProteinModelPortali Q9FXE4.
SMRi Q9FXE4. Positions 121-440.
ModBasei Search...

Protein-protein interaction databases

STRINGi 3702.AT1G67820.1-P.

Proteomic databases

PaxDbi Q9FXE4.
PRIDEi Q9FXE4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G67820.1 ; AT1G67820.1 ; AT1G67820 .
GeneIDi 843108.
KEGGi ath:AT1G67820.

Organism-specific databases

TAIRi AT1G67820.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000090868.
InParanoidi Q9FXE4.
OMAi DMEFLVL.
PhylomeDBi Q9FXE4.

Enzyme and pathway databases

BioCyci ARA:AT1G67820-MONOMER.

Gene expression databases

ArrayExpressi Q9FXE4.
Genevestigatori Q9FXE4.

Family and domain databases

Gene3Di 3.60.40.10. 2 hits.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
    Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
    Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C14_ARATH
AccessioniPrimary (citable) accession number: Q9FXE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: May 14, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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