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Q9FX32

- SUS6_ARATH

UniProt

Q9FX32 - SUS6_ARATH

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Protein
Sucrose synthase 6
Gene
SUS6, At1g73370, T9L24.42
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements.1 Publication

Catalytic activityi

NDP-glucose + D-fructose = NDP + sucrose.

Kineticsi

  1. KM=12.44 mM for D-fructose (synthetic reaction)1 Publication
  2. KM=0.06 mM for UDP-glucose (synthetic reaction)
  3. KM=31.06 mM for sucrose (degradative reaction)
  4. KM=0.26 mM for UDP (degradative reaction)

Vmax=3.27 µmol/min/mg enzyme for synthetic reaction

Vmax=1.43 µmol/min/mg enzyme for degradative reaction

pH dependencei

Optimum pH is 6.0-7.0 for degradative reaction and 7.0 (PubMed:22184213) or 9.0-9.5 (1 Publication) for synthetic reaction.

GO - Molecular functioni

  1. sucrose synthase activity Source: TAIR
Complete GO annotation...

GO - Biological processi

  1. biosynthetic process Source: InterPro
  2. callose deposition in phloem sieve plate Source: TAIR
  3. sucrose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciARA:GQT-78-MONOMER.
MetaCyc:AT1G73370-MONOMER.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Sucrose synthase 6 (EC:2.4.1.13)
Short name:
AtSUS6
Alternative name(s):
Sucrose-UDP glucosyltransferase 6
Gene namesi
Name:SUS6
Ordered Locus Names:At1g73370
ORF Names:T9L24.42
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G73370.

Subcellular locationi

Secretedcell wall 1 Publication

GO - Cellular componenti

  1. cell wall Source: TAIR
  2. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 942942Sucrose synthase 6
PRO_0000418805Add
BLAST

Proteomic databases

PaxDbiQ9FX32.
PRIDEiQ9FX32.

Expressioni

Tissue specificityi

Detected in the whole plant but more precisely confined to the vasculature in cotyledons, leaves, petals, anthers and roots.4 Publications

Gene expression databases

GenevestigatoriQ9FX32.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G73370.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9FX32.
SMRiQ9FX32. Positions 41-812.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni281 – 759479GT-B glycosyltransferase By similarity
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0438.
HOGENOMiHOG000240125.
InParanoidiQ9FX32.
KOiK00695.
OMAiFFEKCKT.
PhylomeDBiQ9FX32.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR000368. Sucrose_synth.
IPR012820. Sucrose_synthase_pln/cyn.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
PF00862. Sucrose_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02470. sucr_synth. 1 hit.

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9FX32-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSSSSQAMLQ KSDSIAEKMP DALKQSRYHM KRCFASFVGG GKKLMKREHL    50
MNEIEKCIED SRERSKILEG LFGYILTCTQ EAAVVPPFVA LAARPNPGFW 100
EYVKVNSGDL TVDEITATDY LKLKESVFDE SWSKDENALE IDFGAIDFTS 150
PRLSLSSSIG KGADYISKFI SSKLGGKSDK LEPLLNYLLR LNHHGENLMI 200
NDDLNTVAKL QKSLMLAVIV VSTYSKHTPY ETFAQRLKEM GFEKGWGDTA 250
ERVKETMIIL SEVLEAPDNG KLDLLFSRLP TVFNVVIFSV HGYFGQQDVL 300
GLPDTGGQVV YILDQVRALE EELLIRINQQ GLGFKPQILV VTRLIPEARG 350
TKCDQELEAI EGTKHSHILR VPFVTNKGVL RQWVSRFDIY PYLERFTQDA 400
TSKILQRLDC KPDLIIGNYT DGNLVASLMA TKLGVTQGTI AHALEKTKYE 450
DSDAKWKELD PKYHFSCQFT ADLIAMNVTD FIITSTYQEI AGSKDRPGQY 500
ESHTAFTMPG LCRVVSGIDV FDPKFNIAAP GADQSVYFPY TEKDKRFTKF 550
HPSIQELLYN EKDNAEHMGY LADREKPIIF SMARLDTVKN ITGLVEWYGK 600
DKRLREMANL VVVAGFFDMS KSNDREEKAE IKKMHDLIEK YKLKGKFRWI 650
AAQTDRYRNS ELYRCIADTK GVFVQPALYE AFGLTVIEAM NCGLPTFATN 700
QGGPAEIIVD GVSGFHIDPN NGDESVTKIG DFFSKCRSDG LYWDNISKGG 750
LKRIYECYTW KIYAEKLLKM GSLYGFWRQV NEDQKKAKKR YIEMLYNLQF 800
KQLTKKVTIP EDKPLPLRLA SLRNLLPKKT TNLGAGSKQK EVTETEKTKQ 850
KSKDGQEQHD VKVGEREVRE GLLAADASER VKKVLESSEE KQKLEKMKIA 900
YGQQHSQGAS PVRNLFWSVV VCLYICYILK QRFFGANSAQ EY 942
Length:942
Mass (Da):106,876
Last modified:March 1, 2001 - v1
Checksum:i0AA4A92EC48815EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012396 Genomic DNA. Translation: AAG30975.1.
CP002684 Genomic DNA. Translation: AEE35450.1.
PIRiC96760.
RefSeqiNP_177480.1. NM_105997.1. [Q9FX32-1]
UniGeneiAt.34995.
At.69495.

Genome annotation databases

EnsemblPlantsiAT1G73370.1; AT1G73370.1; AT1G73370. [Q9FX32-1]
GeneIDi843672.
KEGGiath:AT1G73370.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012396 Genomic DNA. Translation: AAG30975.1 .
CP002684 Genomic DNA. Translation: AEE35450.1 .
PIRi C96760.
RefSeqi NP_177480.1. NM_105997.1. [Q9FX32-1 ]
UniGenei At.34995.
At.69495.

3D structure databases

ProteinModelPortali Q9FX32.
SMRi Q9FX32. Positions 41-812.
ModBasei Search...

Protein-protein interaction databases

STRINGi 3702.AT1G73370.1-P.

Protein family/group databases

CAZyi GT4. Glycosyltransferase Family 4.

Proteomic databases

PaxDbi Q9FX32.
PRIDEi Q9FX32.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G73370.1 ; AT1G73370.1 ; AT1G73370 . [Q9FX32-1 ]
GeneIDi 843672.
KEGGi ath:AT1G73370.

Organism-specific databases

TAIRi AT1G73370.

Phylogenomic databases

eggNOGi COG0438.
HOGENOMi HOG000240125.
InParanoidi Q9FX32.
KOi K00695.
OMAi FFEKCKT.
PhylomeDBi Q9FX32.

Enzyme and pathway databases

BioCyci ARA:GQT-78-MONOMER.
MetaCyc:AT1G73370-MONOMER.

Gene expression databases

Genevestigatori Q9FX32.

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
IPR000368. Sucrose_synth.
IPR012820. Sucrose_synthase_pln/cyn.
[Graphical view ]
Pfami PF00534. Glycos_transf_1. 1 hit.
PF00862. Sucrose_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02470. sucr_synth. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Structure and expression profile of the sucrose synthase multigene family in Arabidopsis."
    Baud S., Vaultier M.N., Rochat C.
    J. Exp. Bot. 55:397-409(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, TISSUE SPECIFICITY.
  4. Cited for: BIOPHYSICOCHEMICAL PROPERTIES, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.
  5. "Localization of sucrose synthase in developing seed and siliques of Arabidopsis thaliana reveals diverse roles for SUS during development."
    Fallahi H., Scofield G.N., Badger M.R., Chow W.S., Furbank R.T., Ruan Y.L.
    J. Exp. Bot. 59:3283-3295(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  6. Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY, FUNCTION.

Entry informationi

Entry nameiSUS6_ARATH
AccessioniPrimary (citable) accession number: Q9FX32
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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