Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 12

Gene

At1g47380

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi69Manganese 1By similarity1
Metal bindingi69Manganese 2By similarity1
Metal bindingi70Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi245Manganese 2By similarity1
Metal bindingi284Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 12 (EC:3.1.3.16)
Short name:
AtPP2C12
Gene namesi
Ordered Locus Names:At1g47380
ORF Names:T3F24.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G47380.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679431 – 428Probable protein phosphatase 2C 12Add BLAST428

Proteomic databases

PaxDbiQ9FX08.

PTM databases

iPTMnetiQ9FX08.

Expressioni

Gene expression databases

GenevisibleiQ9FX08. AT.

Interactioni

Protein-protein interaction databases

BioGridi26366. 1 interactor.
STRINGi3702.AT1G47380.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FX08.
SMRiQ9FX08.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 293PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST270

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000240114.
InParanoidiQ9FX08.
OMAiGCFEPDV.
OrthoDBiEOG09360AH0.
PhylomeDBiQ9FX08.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FX08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKGEHHTV PLSVLLKRES ANEKIDNPEL IHGQHNQSKK GEDFTLVKTE
60 70 80 90 100
CQRVMGDGVT TFSVFGLFDG HNGSAAAIYT KENLLNNVLA AIPSDLNRDE
110 120 130 140 150
WVAALPRALV AGFVKTDKDF QERARTSGTT VTFVIVEGWV VSVASVGDSR
160 170 180 190 200
CILEPAEGGV YYLSADHRLE INEEERDRVT ASGGEVGRLN TGGGTEIGPL
210 220 230 240 250
RCWPGGLCLS RSIGDLDVGE YIVPVPYVKQ VKLSSAGGRL IISSDGVWDA
260 270 280 290 300
ISAEEALDCC RGLPPESSAE HIVKEAVGKK GIRDDTTCIV VDILPLEKPA
310 320 330 340 350
ASVPPPKKQG KGMLKSMFKR KTSDSSSNIE KEYAEPDVVE ELFEEGSAML
360 370 380 390 400
SERLDTKYPL CNMFKLFMCA VCQVEVKPGE GVSIHAGSDN CRKLRPWDGP
410 420
FLCASCQDKK DAMEGKRSSG DRHSSESD
Length:428
Mass (Da):46,422
Last modified:March 1, 2001 - v1
Checksum:i55062CAA157C9CDB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti121Q → R in AAK92805 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015449 Genomic DNA. Translation: AAG11427.1.
CP002684 Genomic DNA. Translation: AEE32161.1.
AY050868 mRNA. Translation: AAK92805.1.
AY150472 mRNA. Translation: AAN12997.1.
PIRiE96514.
RefSeqiNP_564504.1. NM_103632.3.
UniGeneiAt.16151.

Genome annotation databases

EnsemblPlantsiAT1G47380.1; AT1G47380.1; AT1G47380.
GeneIDi841141.
GrameneiAT1G47380.1; AT1G47380.1; AT1G47380.
KEGGiath:AT1G47380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015449 Genomic DNA. Translation: AAG11427.1.
CP002684 Genomic DNA. Translation: AEE32161.1.
AY050868 mRNA. Translation: AAK92805.1.
AY150472 mRNA. Translation: AAN12997.1.
PIRiE96514.
RefSeqiNP_564504.1. NM_103632.3.
UniGeneiAt.16151.

3D structure databases

ProteinModelPortaliQ9FX08.
SMRiQ9FX08.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi26366. 1 interactor.
STRINGi3702.AT1G47380.1.

PTM databases

iPTMnetiQ9FX08.

Proteomic databases

PaxDbiQ9FX08.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G47380.1; AT1G47380.1; AT1G47380.
GeneIDi841141.
GrameneiAT1G47380.1; AT1G47380.1; AT1G47380.
KEGGiath:AT1G47380.

Organism-specific databases

TAIRiAT1G47380.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000240114.
InParanoidiQ9FX08.
OMAiGCFEPDV.
OrthoDBiEOG09360AH0.
PhylomeDBiQ9FX08.

Miscellaneous databases

PROiQ9FX08.

Gene expression databases

GenevisibleiQ9FX08. AT.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C12_ARATH
AccessioniPrimary (citable) accession number: Q9FX08
Secondary accession number(s): Q949V4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2001
Last modified: November 30, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.