CYN

Functionⁱ

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.UniRule annotation

Catalytic activityⁱ

Cyanate + HCO₃^- + 2 H⁺ = NH₃ + 2 CO₂.UniRule annotation

Sites

Feature key	Position(s)	DescriptionActions	Length
Active siteⁱ	94	UniRule annotation	1
Active siteⁱ	97	UniRule annotation	1
Active siteⁱ	120	UniRule annotation	1

GO - Molecular functionⁱ

cyanate hydratase activity
Source: CACAO
Inferred from direct assayⁱ
- 21494323
DNA binding Source: InterPro
identical protein binding Source: EnsemblPlants

Complete GO annotation...

GO - Biological processⁱ

cyanate catabolic process Source: EnsemblPlants
response to salt stress Source: EnsemblPlants

Complete GO annotation...

Keywordsⁱ

Molecular function	Lyase

Molecular function

Lyase

Enzyme and pathway databases

BRENDAⁱ	4.2.1.104. 4460.

BRENDAⁱ

4.2.1.104. 4460.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cyanate hydrataseUniRule annotation (EC:4.2.1.104UniRule annotation) Short name: CyanaseUniRule annotation Alternative name(s): Cyanate hydrolaseUniRule annotation Cyanate lyaseUniRule annotation
Gene namesⁱ	Name:CYNUniRule annotation Ordered Locus Names:Os10g0471300, LOC_Os10g33270 ORF Names:OsJ_31860, OSJNBa0079L16.19
Organismⁱ	Oryza sativa subsp. japonica (Rice)
Taxonomic identifierⁱ	39947 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › Liliopsida › Petrosaviidae › commelinids › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa
Proteomesⁱ	UP000059680 Componentⁱ: Chromosome 10

Subcellular locationⁱ

GO - Cellular componentⁱ

cytosol Source: EnsemblPlants

Complete GO annotation...

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000187535	1 – 168	Cyanate hydrataseAdd BLAST		168

Proteomic databases

PaxDbⁱ	Q9FWK4.
PRIDEⁱ	Q9FWK4.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q9FWK4. OS.

Genevisibleⁱ

Q9FWK4. OS.

Interactionⁱ

GO - Molecular functionⁱ

identical protein binding Source: EnsemblPlants

Complete GO annotation...

Protein-protein interaction databases

STRINGⁱ	39947.LOC_Os10g33270.1.

STRINGⁱ

39947.LOC_Os10g33270.1.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9FWK4.
SMRⁱ	Q9FWK4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the cyanase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG410IWK0. Eukaryota. COG1513. LUCA.
HOGENOMⁱ	HOG000043436.
InParanoidⁱ	Q9FWK4.
KEGG Orthology (KO) More...KOⁱ	K01725.
OMAⁱ	ITMSGKF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG09360QQX.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00559. Cyanase_C. 1 hit.
Gene3Dⁱ	3.30.1160.10. 1 hit.
HAMAPⁱ	MF_00535. Cyanate_hydrat. 1 hit.
InterProⁱ	View protein in InterPro IPR008076. Cyanase. IPR003712. Cyanate_lyase_C. IPR010982. Lambda_DNA-bd_dom.
PANTHERⁱ	PTHR34186. PTHR34186. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02560. Cyanate_lyase. 1 hit.
PIRSFⁱ	PIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSⁱ	PR01693. CYANASE.
SMARTⁱ	View protein in SMART SM01116. Cyanate_lyase. 1 hit.
SUPFAMⁱ	SSF47413. SSF47413. 1 hit. SSF55234. SSF55234. 1 hit.
TIGRFAMsⁱ	TIGR00673. cynS. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9FWK4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEGGGGERAA GVVRRLMAAK AESRKSFSEI GEEAGLTNVY VAQLLRRQAQ 
        60         70         80         90        100
LKPETAPALR AAVPGLTDDL VALMMEPPFR SYHPDIVHEP AIYRLNEAVM 
       110        120        130        140        150
HFGESIKEII NEEFGDGIMS AIDFYCSVDK VQGADGKDRV VVTFDGKYLP 
       160 
YSEQRSDHMM SRLTRKTS

Length:168

Mass (Da):18,608

Last modified:January 31, 2002 - v2

Checksum:ⁱ09492E5A2CF39EE5

GO

Sequence cautionⁱ

The sequence AAG21913 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC026815 Genomic DNA. Translation: AAG21913.1. Sequence problems. DP000086 Genomic DNA. Translation: ABB47779.1. AP008216 Genomic DNA. Translation: BAF26741.1. AP014966 Genomic DNA. Translation: BAT11259.1. CM000147 Genomic DNA. Translation: EAZ16394.1. AK105134 mRNA. Translation: BAG97107.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_015614137.1. XM_015758651.1.
UniGeneⁱ	Os.54423.

Genome annotation databases

EnsemblPlantsⁱ	OS10T0471300-01; OS10T0471300-01; OS10G0471300.
GeneIDⁱ	4348870.
Grameneⁱ	OS10T0471300-01; OS10T0471300-01; OS10G0471300.
KEGGⁱ	osa:4348870.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC026815 Genomic DNA. Translation: AAG21913.1. Sequence problems. DP000086 Genomic DNA. Translation: ABB47779.1. AP008216 Genomic DNA. Translation: BAF26741.1. AP014966 Genomic DNA. Translation: BAT11259.1. CM000147 Genomic DNA. Translation: EAZ16394.1. AK105134 mRNA. Translation: BAG97107.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_015614137.1. XM_015758651.1.
UniGeneⁱ	Os.54423.

3D structure databases

ProteinModelPortalⁱ	Q9FWK4.
SMRⁱ	Q9FWK4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	39947.LOC_Os10g33270.1.

STRINGⁱ

39947.LOC_Os10g33270.1.

Proteomic databases

PaxDbⁱ	Q9FWK4.
PRIDEⁱ	Q9FWK4.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	OS10T0471300-01; OS10T0471300-01; OS10G0471300.
GeneIDⁱ	4348870.
Grameneⁱ	OS10T0471300-01; OS10T0471300-01; OS10G0471300.
KEGGⁱ	osa:4348870.

Phylogenomic databases

eggNOGⁱ	ENOG410IWK0. Eukaryota. COG1513. LUCA.
HOGENOMⁱ	HOG000043436.
InParanoidⁱ	Q9FWK4.
KEGG Orthology (KO) More...KOⁱ	K01725.
OMAⁱ	ITMSGKF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG09360QQX.

Enzyme and pathway databases

BRENDAⁱ	4.2.1.104. 4460.

BRENDAⁱ

4.2.1.104. 4460.

Gene expression databases

Genevisibleⁱ	Q9FWK4. OS.

Genevisibleⁱ

Q9FWK4. OS.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00559. Cyanase_C. 1 hit.
Gene3Dⁱ	3.30.1160.10. 1 hit.
HAMAPⁱ	MF_00535. Cyanate_hydrat. 1 hit.
InterProⁱ	View protein in InterPro IPR008076. Cyanase. IPR003712. Cyanate_lyase_C. IPR010982. Lambda_DNA-bd_dom.
PANTHERⁱ	PTHR34186. PTHR34186. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02560. Cyanate_lyase. 1 hit.
PIRSFⁱ	PIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSⁱ	PR01693. CYANASE.
SMARTⁱ	View protein in SMART SM01116. Cyanate_lyase. 1 hit.
SUPFAMⁱ	SSF47413. SSF47413. 1 hit. SSF55234. SSF55234. 1 hit.
TIGRFAMsⁱ	TIGR00673. cynS. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CYNS_ORYSJ
Accessionⁱ	Q9FWK4Primary (citable) accession number: Q9FWK4 Secondary accession number(s): A0A0P0XV77 , A3C5N1, Q0IX24, Q337L4, Q7XDI1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 31, 2002
	Last sequence update:	January 31, 2002
	Last modified:	June 7, 2017
	This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9FWK4 (CYNS_ORYSJ)

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Cyanate hydratase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ