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Q9FVC4

- Q9FVC4_ARATH

UniProt

Q9FVC4 - Q9FVC4_ARATH

Protein
Submitted name:

Aspartate-semialdehyde dehydrogenase

Gene

ASDH

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei135 – 1351Acyl-thioester intermediateUniRule annotation
    Active sitei248 – 2481Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. aspartate-semialdehyde dehydrogenase activity Source: UniProtKB-EC
    2. N-acetyl-gamma-glutamyl-phosphate reductase activity Source: InterPro
    3. NAD binding Source: InterPro
    4. NADP binding Source: InterPro

    GO - Biological processi

    1. isoleucine biosynthetic process Source: InterPro
    2. lysine biosynthetic process via diaminopimelate Source: InterPro
    3. methionine biosynthetic process Source: InterPro
    4. threonine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aspartate-semialdehyde dehydrogenaseImported (EC:1.2.1.11Imported)
    Gene namesi
    Name:ASDHImported
    OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 340›340aspartate-semialdehyde dehydrogenaseImportedPRO_5000057619Add
    BLAST

    Expressioni

    Gene expression databases

    ArrayExpressiQ9FVC4.
    GenevestigatoriQ9FVC4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FVC4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aspartate-semialdehyde dehydrogenase family.UniRule annotation

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_02121. ASADH.
    InterProiIPR012080. Asp_semialdehyde_DH.
    IPR005986. Asp_semialdehyde_DH_beta.
    IPR016040. NAD(P)-bd_dom.
    IPR000534. Semialdehyde_DH_NAD-bd.
    IPR012280. Semialdhyde_DH_dimer_dom.
    [Graphical view]
    PfamiPF01118. Semialdhyde_dh. 1 hit.
    PF02774. Semialdhyde_dhC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000148. ASA_dh. 1 hit.
    SMARTiSM00859. Semialdhyde_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01296. asd_B. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q9FVC4-1 [UniParc]FASTAAdd to Basket

    « Hide

    ESAPSLAVVG VTGAVGQEFL SVLSDRDFPY SSIKMLASKR SAGKRVAFDG    50
    HEYTVEELTA DSFNGVDIAL FSAGGSISKE FGPLAAEKGT IVVDNSSAFR 100
    MVDGVPLVIP EVNPEAMKGI KVGMGKGALI ANPNCSTIIC LMAVTPLHHH 150
    AKVKRMVVST YQAASGAGAA AMEELVQQTR EVLEGKPPTC NIFGQQYAFN 200
    LFSHNAPILD NGYNEEEMKL VKETRKIWND TEVKVTATCI RVPVMRAHAE 250
    SVNLQFENPL DENTAREILK KAPGVYIIDD RASNTFPTPL DVSNKDDVAV 300
    GRIRRDVSQD GNFGLDIFVC GDQIRKGAAL NAVQIAEMLL 340
    Length:340
    Mass (Da):36,643
    Last modified:March 1, 2001 - v1
    Checksum:i2D85720BA8D2A196
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF207064 mRNA. Translation: AAG33078.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF207064 mRNA. Translation: AAG33078.1 .

    3D structure databases

    ProteinModelPortali Q9FVC4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q9FVC4.
    Genevestigatori Q9FVC4.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_02121. ASADH.
    InterProi IPR012080. Asp_semialdehyde_DH.
    IPR005986. Asp_semialdehyde_DH_beta.
    IPR016040. NAD(P)-bd_dom.
    IPR000534. Semialdehyde_DH_NAD-bd.
    IPR012280. Semialdhyde_DH_dimer_dom.
    [Graphical view ]
    Pfami PF01118. Semialdhyde_dh. 1 hit.
    PF02774. Semialdhyde_dhC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000148. ASA_dh. 1 hit.
    SMARTi SM00859. Semialdhyde_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01296. asd_B. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana."
      Paris S., Wessel P.M., Dumas R.
      Protein Expr. Purif. 24:99-104(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9FVC4_ARATH
    AccessioniPrimary (citable) accession number: Q9FVC4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)