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Protein

Glutathione S-transferase U17

Gene

GSTU17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in light signaling, mainly phyA-mediated photomorphogenesis and in the integration of various phytohormone signals to modulate various aspects of plant development by affecting glutathione pools. In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC).1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione transferase activity Source: TAIR

GO - Biological processi

  • de-etiolation Source: TAIR
  • glutathione metabolic process Source: TAIR
  • lateral root development Source: TAIR
  • negative regulation of response to water deprivation Source: TAIR
  • regulation of growth Source: UniProtKB-KW
  • response to growth hormone Source: TAIR
  • response to karrikin Source: TAIR
  • response to salt stress Source: TAIR
  • response to toxic substance Source: UniProtKB-KW
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification, Growth regulation, Stress response

Enzyme and pathway databases

BioCyciARA:AT1G10370-MONOMER.
BRENDAi2.5.1.18. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U17 (EC:2.5.1.18)
Short name:
AtGSTU17
Alternative name(s):
GST class-tau member 17
Glutathione S-transferase 30
Protein EARLY RESPONSIVE TO DEHYDRATION 9
Gene namesi
Name:GSTU17
Synonyms:ERD9, GST30, GST30B
Ordered Locus Names:At1g10370
ORF Names:F14N23.26
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G10370.
TAIRilocus:2012773. AT1G10370.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: TAIR
  • cytoplasm Source: TAIR
  • cytosol Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

Delayed flowering, long-hypocotyl phenotype under low fluences of far-red light and insensitive to ABA-mediated inhibition of root elongation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135631 – 227Glutathione S-transferase U17Add BLAST227

Proteomic databases

PaxDbiQ9FUS8.

Expressioni

Inductioni

By dehydration stress, auxin, abscisic acid (ABA), jasmonate, ozone and transition from dark to far-red and red light.3 Publications

Gene expression databases

ExpressionAtlasiQ9FUS8. baseline and differential.
GenevisibleiQ9FUS8. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G10370.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FUS8.
SMRiQ9FUS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 83GST N-terminalAdd BLAST80
Domaini90 – 222GST C-terminalAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni14 – 15Glutathione bindingBy similarity2
Regioni40 – 41Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406. Eukaryota.
ENOG410XSIX. LUCA.
HOGENOMiHOG000125749.
InParanoidiQ9FUS8.
KOiK00799.
OMAiKHAASMK.
OrthoDBiEOG09360N01.
PhylomeDBiQ9FUS8.

Family and domain databases

InterProiView protein in InterPro
IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
PfamiView protein in Pfam
PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9FUS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSDVKLIG AWASPFVMRP RIALNLKSVP YEFLQETFGS KSELLLKSNP
60 70 80 90 100
VHKKIPVLLH ADKPVSESNI IVEYIDDTWS SSGPSILPSD PYDRAMARFW
110 120 130 140 150
AAYIDEKWFV ALRGFLKAGG EEEKKAVIAQ LEEGNAFLEK AFIDCSKGKP
160 170 180 190 200
FFNGDNIGYL DIALGCFLAW LRVTELAVSY KILDEAKTPS LSKWAENFCN
210 220
DPAVKPVMPE TAKLAEFAKK IFPKPQA
Length:227
Mass (Da):25,307
Last modified:March 1, 2001 - v1
Checksum:i6A1743B849937442
GO

Sequence cautioni

The sequence AAD32888 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti151F → S in BAB63917 (PubMed:8075396).Curated1
Sequence conflicti161D → N in BAB63917 (PubMed:8075396).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB039930 mRNA. Translation: BAB63917.1.
AF288191 mRNA. Translation: AAG30140.1.
AC005489 Genomic DNA. Translation: AAD32888.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE28571.1.
BT023743 mRNA. Translation: AAZ23935.1.
RefSeqiNP_172508.4. NM_100911.6.
UniGeneiAt.11290.

Genome annotation databases

EnsemblPlantsiAT1G10370.1; AT1G10370.1; AT1G10370.
GeneIDi837576.
GrameneiAT1G10370.1; AT1G10370.1; AT1G10370.
KEGGiath:AT1G10370.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiGSTUH_ARATH
AccessioniPrimary (citable) accession number: Q9FUS8
Secondary accession number(s): Q94II0, Q9SY80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: March 1, 2001
Last modified: June 7, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families