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Protein

Sugar transporter ERD6-like 6

Gene

At1g75220

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sugar transporter.Curated

GO - Molecular functioni

GO - Biological processi

  • glucose homeostasis Source: TAIR
  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • positive regulation of seed germination Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.

Protein family/group databases

TCDBi2.A.1.1.98. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Sugar transporter ERD6-like 6
Gene namesi
Ordered Locus Names:At1g75220
ORF Names:F22H5.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G75220.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei46 – 6621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei89 – 10921Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei115 – 13521Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei146 – 16621Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei178 – 19821Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei201 – 22121Helical; Name=6Sequence analysisAdd
BLAST
Transmembranei284 – 30421Helical; Name=7Sequence analysisAdd
BLAST
Transmembranei320 – 34021Helical; Name=8Sequence analysisAdd
BLAST
Transmembranei347 – 36721Helical; Name=9Sequence analysisAdd
BLAST
Transmembranei389 – 40921Helical; Name=10Sequence analysisAdd
BLAST
Transmembranei425 – 44521Helical; Name=11Sequence analysisAdd
BLAST
Transmembranei451 – 47121Helical; Name=12Sequence analysisAdd
BLAST

GO - Cellular componenti

  • Golgi apparatus Source: TAIR
  • integral component of plasma membrane Source: GO_Central
  • plant-type vacuole membrane Source: TAIR
  • vacuolar membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedCombined sources
Chaini2 – 487486Sugar transporter ERD6-like 6PRO_0000259856Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineCombined sources

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9FRL3.
PRIDEiQ9FRL3.

PTM databases

iPTMnetiQ9FRL3.

Expressioni

Gene expression databases

GenevisibleiQ9FRL3. AT.

Interactioni

Protein-protein interaction databases

BioGridi29078. 3 interactions.
IntActiQ9FRL3. 2 interactions.
STRINGi3702.AT1G75220.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FRL3.
SMRiQ9FRL3. Positions 47-486.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ9FRL3.
OMAiISIEVNE.
PhylomeDBiQ9FRL3.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FRL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFRDDNEEA RNDLRRPFIH TGSWYRMGSR QSSMMGSSQV IRDSSISVLA
60 70 80 90 100
CVLIVALGPI QFGFTCGYSS PTQAAITKDL GLTVSEYSVF GSLSNVGAMV
110 120 130 140 150
GAIASGQIAE YIGRKGSLMI AAIPNIIGWL CISFAKDTSF LYMGRLLEGF
160 170 180 190 200
GVGIISYTVP VYIAEIAPQN MRGGLGSVNQ LSVTIGIMLA YLLGLFVPWR
210 220 230 240 250
ILAVLGILPC TLLIPGLFFI PESPRWLAKM GMTDEFETSL QVLRGFETDI
260 270 280 290 300
TVEVNEIKRS VASSTKRNTV RFVDLKRRRY YFPLMVGIGL LVLQQLGGIN
310 320 330 340 350
GVLFYSSTIF ESAGVTSSNA ATFGVGAIQV VATAISTWLV DKAGRRLLLT
360 370 380 390 400
ISSVGMTISL VIVAAAFYLK EFVSPDSDMY SWLSILSVVG VVAMVVFFSL
410 420 430 440 450
GMGPIPWLIM SEILPVNIKG LAGSIATLAN WFFSWLITMT ANLLLAWSSG
460 470 480
GTFTLYGLVC AFTVVFVTLW VPETKGKTLE ELQSLFR
Length:487
Mass (Da):52,901
Last modified:March 1, 2001 - v1
Checksum:i98604E3642914472
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025814 Genomic DNA. Translation: AAG12689.1.
CP002684 Genomic DNA. Translation: AEE35689.1.
AF412060 mRNA. Translation: AAL06513.1.
AY124845 mRNA. Translation: AAM70554.1.
PIRiE96782.
RefSeqiNP_177658.1. NM_106178.3.
UniGeneiAt.22004.

Genome annotation databases

EnsemblPlantsiAT1G75220.1; AT1G75220.1; AT1G75220.
GeneIDi843859.
GrameneiAT1G75220.1; AT1G75220.1; AT1G75220.
KEGGiath:AT1G75220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025814 Genomic DNA. Translation: AAG12689.1.
CP002684 Genomic DNA. Translation: AEE35689.1.
AF412060 mRNA. Translation: AAL06513.1.
AY124845 mRNA. Translation: AAM70554.1.
PIRiE96782.
RefSeqiNP_177658.1. NM_106178.3.
UniGeneiAt.22004.

3D structure databases

ProteinModelPortaliQ9FRL3.
SMRiQ9FRL3. Positions 47-486.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi29078. 3 interactions.
IntActiQ9FRL3. 2 interactions.
STRINGi3702.AT1G75220.1.

Protein family/group databases

TCDBi2.A.1.1.98. the major facilitator superfamily (mfs).

PTM databases

iPTMnetiQ9FRL3.

Proteomic databases

PaxDbiQ9FRL3.
PRIDEiQ9FRL3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G75220.1; AT1G75220.1; AT1G75220.
GeneIDi843859.
GrameneiAT1G75220.1; AT1G75220.1; AT1G75220.
KEGGiath:AT1G75220.

Organism-specific databases

TAIRiAT1G75220.

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
HOGENOMiHOG000202868.
InParanoidiQ9FRL3.
OMAiISIEVNE.
PhylomeDBiQ9FRL3.

Enzyme and pathway databases

ReactomeiR-ATH-428790. Facilitative Na+-independent glucose transporters.

Miscellaneous databases

PROiQ9FRL3.

Gene expression databases

GenevisibleiQ9FRL3. AT.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages."
    Johnson D.A., Hill J.P., Thomas M.A.
    BMC Evol. Biol. 6:64-64(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  5. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiERDL6_ARATH
AccessioniPrimary (citable) accession number: Q9FRL3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2001
Last modified: July 6, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.