SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9FPS4

- UBP23_ARATH

UniProt

Q9FPS4 - UBP23_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Ubiquitin carboxyl-terminal hydrolase 23
Gene
UBP23, At5g57990, MTI20.25
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins By similarity.

Catalytic activityi

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei116 – 1161Nucleophile By similarity
Active sitei369 – 3691Proton acceptor By similarity

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
  2. ubiquitinyl hydrolase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

BioCyciARA:AT5G57990-MONOMER.

Protein family/group databases

MEROPSiC19.A12.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin carboxyl-terminal hydrolase 23 (EC:3.4.19.12)
Alternative name(s):
Deubiquitinating enzyme 23
Short name:
AtUBP23
Ubiquitin thioesterase 23
Ubiquitin-specific-processing protease 23
Gene namesi
Name:UBP23
Ordered Locus Names:At5g57990
ORF Names:MTI20.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G57990.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 859859Ubiquitin carboxyl-terminal hydrolase 23
PRO_0000313049Add
BLAST

Proteomic databases

PaxDbiQ9FPS4.
PRIDEiQ9FPS4.

Expressioni

Gene expression databases

GenevestigatoriQ9FPS4.

Structurei

3D structure databases

ProteinModelPortaliQ9FPS4.
SMRiQ9FPS4. Positions 108-407.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini107 – 410304USP
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi814 – 8174Poly-Lys

Sequence similaritiesi

Belongs to the peptidase C19 family.
Contains 1 USP domain.

Phylogenomic databases

eggNOGiCOG5077.
HOGENOMiHOG000078724.
InParanoidiQ9FPS4.
KOiK11855.
OMAiAHEYMIN.
PhylomeDBiQ9FPS4.

Family and domain databases

InterProiIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view]
PfamiPF00443. UCH. 1 hit.
[Graphical view]
PROSITEiPS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FPS4-1 [UniParc]FASTAAdd to Basket

« Hide

MEVATSSTEI TIQTDRDPSS NNNGSCAVAS STASAVFRKI EFHPARKPFN    50
GFSNGRSDFK IETLNPCSSN QRLLSAPSAK KPDSSDLLEH GFEPDLTFSI 100
TFRKIGAGLQ NLGNTCFLNS VLQCLTYTEP LAATLQTAAH QKYCHVAGFC 150
ALCAIQKHVR TARQANGRIL APKDLVSNLR CISRNFRNCR QEDAHEYMIN 200
LLECMHKCSL PSGVPSESSD AYRRSLVHKI FGGSLRSQVK CEQCSHCSNK 250
FDPFLDLSLD ISKADSLQRA LSRFTAVELL DNGAKVYQCE RCKQKVKAKK 300
QLTVSKAPYV LTVHLKRFEA HRSEKIDRKV DFTSAIDMKP FVSGPHEGNL 350
KYTLYGVLVH YGRSSHSGHY ACFVRTSSGM WYSLDDNRVV QVSEKTVFNQ 400
KAYMLFYVRD RQNAVPKNSV PVVKKESFAT NRASLIVASN IKDQVNGSTV 450
IKECGFGALV ANGLAPLKSC GPSTPAVLTQ KDLNAKETQN NAISNVEAKE 500
ILETENGSAP VKTCDLAAPT VLVQKDLNTK EIFQKEVPLP QANGEGSLVK 550
EDSKAACLIL PEKVSPHLDG SANAQTLVKL PTLGPKAENS VEEKNSLNNL 600
NEPANSLKVI NVSVGNPPVE KAVLIDQTMG HHLEESATSI ESLKLTSERE 650
TLTTPKKTRK PKTKTLKVEF KFFKLALGLR KKKVQRRERL STTVAGEIIS 700
EELLSKKRVK YQDTSLIAPS KMISSSDGAV TSDQQQPVGS SDLSEASQNA 750
KRKRESVLLQ KEAVNILTRG VPETVVAKWD EEISASQKRG SKSEGASSIG 800
YVADEWDEEY DRGKKKKIRI KEESYRGPNP FQMLASKRQK ETKKKWTQSI 850
TDAKTAYRI 859
Length:859
Mass (Da):94,903
Last modified:January 15, 2008 - v2
Checksum:i046FE8764DBB4609
GO

Sequence cautioni

The sequence BAB08869.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti657 – 6571K → N in AAG42761. 1 Publication
Sequence conflicti660 – 6601K → E in AAG42761. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF302671 mRNA. Translation: AAG42761.1.
AB013396 Genomic DNA. Translation: BAB08869.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96982.1.
RefSeqiNP_568873.1. NM_125184.2.
UniGeneiAt.22531.

Genome annotation databases

EnsemblPlantsiAT5G57990.1; AT5G57990.1; AT5G57990.
GeneIDi835910.
KEGGiath:AT5G57990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF302671 mRNA. Translation: AAG42761.1 .
AB013396 Genomic DNA. Translation: BAB08869.1 . Sequence problems.
CP002688 Genomic DNA. Translation: AED96982.1 .
RefSeqi NP_568873.1. NM_125184.2.
UniGenei At.22531.

3D structure databases

ProteinModelPortali Q9FPS4.
SMRi Q9FPS4. Positions 108-407.
ModBasei Search...

Protein family/group databases

MEROPSi C19.A12.

Proteomic databases

PaxDbi Q9FPS4.
PRIDEi Q9FPS4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G57990.1 ; AT5G57990.1 ; AT5G57990 .
GeneIDi 835910.
KEGGi ath:AT5G57990.

Organism-specific databases

GeneFarmi 1994. 220.
TAIRi AT5G57990.

Phylogenomic databases

eggNOGi COG5077.
HOGENOMi HOG000078724.
InParanoidi Q9FPS4.
KOi K11855.
OMAi AHEYMIN.
PhylomeDBi Q9FPS4.

Enzyme and pathway databases

BioCyci ARA:AT5G57990-MONOMER.

Gene expression databases

Genevestigatori Q9FPS4.

Family and domain databases

InterProi IPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view ]
Pfami PF00443. UCH. 1 hit.
[Graphical view ]
PROSITEi PS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The ubiquitin-specific protease family from Arabidopsis. AtUBP1 and 2 are required for the resistance to the amino acid analog canavanine."
    Yan N., Doelling J.H., Falbel T.G., Durski A.M., Vierstra R.D.
    Plant Physiol. 124:1828-1843(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY ORGANIZATION, NOMENCLATURE.
    Strain: cv. Columbia.
  2. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
    Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
    DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiUBP23_ARATH
AccessioniPrimary (citable) accession number: Q9FPS4
Secondary accession number(s): Q9FJL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: September 3, 2014
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi