Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9FPS4

- UBP23_ARATH

UniProt

Q9FPS4 - UBP23_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ubiquitin carboxyl-terminal hydrolase 23

Gene

UBP23

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins By similarity.By similarity

Catalytic activityi

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei116 – 1161NucleophilePROSITE-ProRule annotation
Active sitei369 – 3691Proton acceptorPROSITE-ProRule annotation

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
  2. ubiquitinyl hydrolase activity Source: InterPro

GO - Biological processi

  1. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

BioCyciARA:AT5G57990-MONOMER.

Protein family/group databases

MEROPSiC19.A12.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin carboxyl-terminal hydrolase 23 (EC:3.4.19.12)
Alternative name(s):
Deubiquitinating enzyme 23
Short name:
AtUBP23
Ubiquitin thioesterase 23
Ubiquitin-specific-processing protease 23
Gene namesi
Name:UBP23
Ordered Locus Names:At5g57990
ORF Names:MTI20.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G57990.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 859859Ubiquitin carboxyl-terminal hydrolase 23PRO_0000313049Add
BLAST

Proteomic databases

PaxDbiQ9FPS4.
PRIDEiQ9FPS4.

Expressioni

Gene expression databases

GenevestigatoriQ9FPS4.

Structurei

3D structure databases

ProteinModelPortaliQ9FPS4.
SMRiQ9FPS4. Positions 108-407.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini107 – 410304USPAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi814 – 8174Poly-Lys

Sequence similaritiesi

Belongs to the peptidase C19 family.Curated
Contains 1 USP domain.Curated

Phylogenomic databases

eggNOGiCOG5077.
HOGENOMiHOG000078724.
InParanoidiQ9FPS4.
KOiK11855.
OMAiAHEYMIN.
PhylomeDBiQ9FPS4.

Family and domain databases

InterProiIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view]
PfamiPF00443. UCH. 1 hit.
[Graphical view]
PROSITEiPS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FPS4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEVATSSTEI TIQTDRDPSS NNNGSCAVAS STASAVFRKI EFHPARKPFN
60 70 80 90 100
GFSNGRSDFK IETLNPCSSN QRLLSAPSAK KPDSSDLLEH GFEPDLTFSI
110 120 130 140 150
TFRKIGAGLQ NLGNTCFLNS VLQCLTYTEP LAATLQTAAH QKYCHVAGFC
160 170 180 190 200
ALCAIQKHVR TARQANGRIL APKDLVSNLR CISRNFRNCR QEDAHEYMIN
210 220 230 240 250
LLECMHKCSL PSGVPSESSD AYRRSLVHKI FGGSLRSQVK CEQCSHCSNK
260 270 280 290 300
FDPFLDLSLD ISKADSLQRA LSRFTAVELL DNGAKVYQCE RCKQKVKAKK
310 320 330 340 350
QLTVSKAPYV LTVHLKRFEA HRSEKIDRKV DFTSAIDMKP FVSGPHEGNL
360 370 380 390 400
KYTLYGVLVH YGRSSHSGHY ACFVRTSSGM WYSLDDNRVV QVSEKTVFNQ
410 420 430 440 450
KAYMLFYVRD RQNAVPKNSV PVVKKESFAT NRASLIVASN IKDQVNGSTV
460 470 480 490 500
IKECGFGALV ANGLAPLKSC GPSTPAVLTQ KDLNAKETQN NAISNVEAKE
510 520 530 540 550
ILETENGSAP VKTCDLAAPT VLVQKDLNTK EIFQKEVPLP QANGEGSLVK
560 570 580 590 600
EDSKAACLIL PEKVSPHLDG SANAQTLVKL PTLGPKAENS VEEKNSLNNL
610 620 630 640 650
NEPANSLKVI NVSVGNPPVE KAVLIDQTMG HHLEESATSI ESLKLTSERE
660 670 680 690 700
TLTTPKKTRK PKTKTLKVEF KFFKLALGLR KKKVQRRERL STTVAGEIIS
710 720 730 740 750
EELLSKKRVK YQDTSLIAPS KMISSSDGAV TSDQQQPVGS SDLSEASQNA
760 770 780 790 800
KRKRESVLLQ KEAVNILTRG VPETVVAKWD EEISASQKRG SKSEGASSIG
810 820 830 840 850
YVADEWDEEY DRGKKKKIRI KEESYRGPNP FQMLASKRQK ETKKKWTQSI

TDAKTAYRI
Length:859
Mass (Da):94,903
Last modified:January 15, 2008 - v2
Checksum:i046FE8764DBB4609
GO

Sequence cautioni

The sequence BAB08869.1 differs from that shown. Reason: Erroneous gene model prediction.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti657 – 6571K → N in AAG42761. (PubMed:11115897)Curated
Sequence conflicti660 – 6601K → E in AAG42761. (PubMed:11115897)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF302671 mRNA. Translation: AAG42761.1.
AB013396 Genomic DNA. Translation: BAB08869.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96982.1.
RefSeqiNP_568873.1. NM_125184.2.
UniGeneiAt.22531.

Genome annotation databases

EnsemblPlantsiAT5G57990.1; AT5G57990.1; AT5G57990.
GeneIDi835910.
KEGGiath:AT5G57990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF302671 mRNA. Translation: AAG42761.1 .
AB013396 Genomic DNA. Translation: BAB08869.1 . Sequence problems.
CP002688 Genomic DNA. Translation: AED96982.1 .
RefSeqi NP_568873.1. NM_125184.2.
UniGenei At.22531.

3D structure databases

ProteinModelPortali Q9FPS4.
SMRi Q9FPS4. Positions 108-407.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi C19.A12.

Proteomic databases

PaxDbi Q9FPS4.
PRIDEi Q9FPS4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G57990.1 ; AT5G57990.1 ; AT5G57990 .
GeneIDi 835910.
KEGGi ath:AT5G57990.

Organism-specific databases

GeneFarmi 1994. 220.
TAIRi AT5G57990.

Phylogenomic databases

eggNOGi COG5077.
HOGENOMi HOG000078724.
InParanoidi Q9FPS4.
KOi K11855.
OMAi AHEYMIN.
PhylomeDBi Q9FPS4.

Enzyme and pathway databases

BioCyci ARA:AT5G57990-MONOMER.

Gene expression databases

Genevestigatori Q9FPS4.

Family and domain databases

InterProi IPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view ]
Pfami PF00443. UCH. 1 hit.
[Graphical view ]
PROSITEi PS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The ubiquitin-specific protease family from Arabidopsis. AtUBP1 and 2 are required for the resistance to the amino acid analog canavanine."
    Yan N., Doelling J.H., Falbel T.G., Durski A.M., Vierstra R.D.
    Plant Physiol. 124:1828-1843(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY ORGANIZATION, NOMENCLATURE.
    Strain: cv. Columbia.
  2. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
    Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
    DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiUBP23_ARATH
AccessioniPrimary (citable) accession number: Q9FPS4
Secondary accession number(s): Q9FJL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 1, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3