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Protein

Homeobox protein knotted-1-like 7

Gene

KNAT7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in secondary cell wall biosynthesis.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi215 – 27864Homeobox; TALE-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • mucilage biosynthetic process Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • regulation of secondary cell wall biogenesis Source: TAIR
  • xylem development Source: TAIR
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein knotted-1-like 7
Alternative name(s):
Protein IRREGULAR XYLEM 11
Protein KNAT7
Gene namesi
Name:KNAT7
Synonyms:IRX11
Ordered Locus Names:At1g62990
ORF Names:F16P17.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G62990.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 291291Homeobox protein knotted-1-like 7PRO_0000314775Add
BLAST

Proteomic databases

PaxDbiQ9FPQ8.
PRIDEiQ9FPQ8.

Expressioni

Gene expression databases

GenevisibleiQ9FPQ8. AT.

Interactioni

Subunit structurei

May form heterodimeric complex with the TALE/BELL proteins (By similarity). Interacts with OFP1, OFP2, OFP3, OFP4 and OFP6.By similarity1 Publication

Protein-protein interaction databases

BioGridi27823. 22 interactions.
IntActiQ9FPQ8. 20 interactions.
STRINGi3702.AT1G62990.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FPQ8.
SMRiQ9FPQ8. Positions 217-273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini194 – 21421ELKPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TALE/KNOX homeobox family.PROSITE-ProRule annotation
Contains 1 ELK domain.PROSITE-ProRule annotation
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
HOGENOMiHOG000272741.
InParanoidiQ9FPQ8.
OMAiHERQELD.
OrthoDBiEOG09360IWU.
PhylomeDBiQ9FPQ8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR005539. ELK_dom.
IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR005540. KNOX1.
IPR005541. KNOX2.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF03790. KNOX1. 1 hit.
PF03791. KNOX2. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM01255. KNOX1. 1 hit.
SM01256. KNOX2. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51213. ELK. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FPQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEAALGMMG ATVGGDGDTA VVAEQNRQLK GEIATHPMYE QLLAAHVACL
60 70 80 90 100
RVATPIDQLP IIEAQLSQSH HLLRSYASTA VGYHHDRHEL DNFLAQYVMV
110 120 130 140 150
LCSFKEQLQQ HVRVHAVEAV MACREIENNL HSLTGATLGE GSGATMSEDE
160 170 180 190 200
DDLPMDFSSD NSGVDFSGGH DMTGFGPLLP TESERSLMER VRQELKLELK
210 220 230 240 250
QGFKSRIEDV REEIMRKRRA GKLPGDTTTV LKNWWQQHCK WPYPTEDDKA
260 270 280 290
KLVEETGLQL KQINNWFINQ RKRNWHNNSH SLTSLKSKRK H
Length:291
Mass (Da):32,908
Last modified:March 1, 2001 - v1
Checksum:i1F473BEEE07F2B62
GO

Sequence cautioni

The sequence AAF75812 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAM67281 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC42940 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1 – 11M → L in BAC42940 (PubMed:11910074).Curated
Sequence conflicti12 – 121T → S in AAM67281 (Ref. 6) Curated
Sequence conflicti19 – 191T → A in AAM67281 (Ref. 6) Curated
Sequence conflicti185 – 1851R → K in AAM67281 (Ref. 6) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF308451 mRNA. Translation: AAG40858.1.
AC011000 Genomic DNA. Translation: AAF75812.1. Different initiation.
CP002684 Genomic DNA. Translation: AEE34034.1.
AK118326 mRNA. Translation: BAC42940.1. Different initiation.
BT026059 mRNA. Translation: ABG48415.1.
AY084398 mRNA. Translation: AAM67281.1. Different initiation.
PIRiA96655.
RefSeqiNP_564805.1. NM_104977.2.
UniGeneiAt.70104.

Genome annotation databases

EnsemblPlantsiAT1G62990.1; AT1G62990.1; AT1G62990.
GeneIDi842602.
GrameneiAT1G62990.1; AT1G62990.1; AT1G62990.
KEGGiath:AT1G62990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF308451 mRNA. Translation: AAG40858.1.
AC011000 Genomic DNA. Translation: AAF75812.1. Different initiation.
CP002684 Genomic DNA. Translation: AEE34034.1.
AK118326 mRNA. Translation: BAC42940.1. Different initiation.
BT026059 mRNA. Translation: ABG48415.1.
AY084398 mRNA. Translation: AAM67281.1. Different initiation.
PIRiA96655.
RefSeqiNP_564805.1. NM_104977.2.
UniGeneiAt.70104.

3D structure databases

ProteinModelPortaliQ9FPQ8.
SMRiQ9FPQ8. Positions 217-273.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27823. 22 interactions.
IntActiQ9FPQ8. 20 interactions.
STRINGi3702.AT1G62990.1.

Proteomic databases

PaxDbiQ9FPQ8.
PRIDEiQ9FPQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G62990.1; AT1G62990.1; AT1G62990.
GeneIDi842602.
GrameneiAT1G62990.1; AT1G62990.1; AT1G62990.
KEGGiath:AT1G62990.

Organism-specific databases

TAIRiAT1G62990.

Phylogenomic databases

eggNOGiKOG0773. Eukaryota.
ENOG410XPMQ. LUCA.
HOGENOMiHOG000272741.
InParanoidiQ9FPQ8.
OMAiHERQELD.
OrthoDBiEOG09360IWU.
PhylomeDBiQ9FPQ8.

Miscellaneous databases

PROiQ9FPQ8.

Gene expression databases

GenevisibleiQ9FPQ8. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR005539. ELK_dom.
IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR005540. KNOX1.
IPR005541. KNOX2.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF03790. KNOX1. 1 hit.
PF03791. KNOX2. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM01255. KNOX1. 1 hit.
SM01256. KNOX2. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51213. ELK. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKNAT7_ARATH
AccessioniPrimary (citable) accession number: Q9FPQ8
Secondary accession number(s): Q8GXB5, Q8LG94, Q9LQ05
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.